Results 11 to 20 of about 266,501 (296)

Cardiac Electrophysiological Effects of Light-Activated Chloride Channels [PDF]

open access: yesFrontiers in Physiology, 2018
During the last decade, optogenetics has emerged as a paradigm-shifting technique to monitor and steer the behavior of specific cell types in excitable tissues, including the heart.
Ramona A. Kopton   +17 more
doaj   +2 more sources

Chloride – The Underrated Ion in Nociceptors

open access: yesFrontiers in Neuroscience, 2020
In contrast to pain processing neurons in the spinal cord, where the importance of chloride conductances is already well established, chloride homeostasis in primary afferent neurons has received less attention.
Bettina U. Wilke   +3 more
doaj   +1 more source

A Novel Homozygous Mutation of Classic Bartter Syndrome Presenting with Renal Cysts in 6-year-Old Identical Twin Boys : A Case Report [PDF]

open access: yesChildhood Kidney Diseases, 2021
Bartter syndrome is an autosomal recessive hypokalemic salt-losing tubulopathy, and classic Bartter syndrome is associated with mutations in the CLCNKB gene.
Min Hwa Son, Hyung Eun Yim, Kee Hwan Yoo
doaj   +1 more source

Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex. [PDF]

open access: yesPLoS ONE, 2015
Calcium-activated chloride channels of the anoctamin (alias TMEM16) protein family fulfill critical functions in epithelial fluid transport, smooth muscle contraction and sensory signal processing.
Weiping Zhang   +4 more
doaj   +1 more source

Chloride channels in stroke [PDF]

open access: yesActa Pharmacologica Sinica, 2012
Vascular remodeling of cerebral arterioles, including proliferation, migration, and apoptosis of vascular smooth muscle cells (VSMCs), is the major cause of changes in the cross-sectional area and diameter of the arteries and sudden interruption of blood flow or hemorrhage in the brain, ie, stroke.
Ya-ping, Zhang   +2 more
openaire   +2 more sources

Transcriptomic Analysis Reveals Salt Tolerance Mechanisms Present in Date-Plum Persimmon Rootstock (Diospyros lotus L.)

open access: yesAgronomy, 2020
Agriculture needs solutions for adapting crops to increasing salinity globally. Research on physiological and molecular responses activated by salinity is needed to elucidate mechanisms of salinity tolerance.
Francisco Gil-Muñoz   +5 more
doaj   +1 more source

Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. [PDF]

open access: yesPLoS ONE, 2011
Together, acid-sensing ion channels (ASICs) and epithelial sodium channels (ENaC) constitute the majority of voltage-independent sodium channels in mammals. ENaC is regulated by a chloride channel, the cystic fibrosis transmembrane conductance regulator (
Xuanmao Chen   +3 more
doaj   +1 more source

secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila [PDF]

open access: yes, 2019
Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products.
Dent, J.   +6 more
core   +2 more sources

Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon

open access: yeseLife, 2018
Light-gated chloride channels are emerging as promising optogenetic tools for inhibition of neural activity. However, their effects depend on the transmembrane chloride electrochemical gradient and may be complex due to the heterogeneity of this gradient
Jessica E Messier   +3 more
doaj   +1 more source

A chloride channel in rat and human axons [PDF]

open access: yes, 1991
Current recordings from single chloride channels were obtained from excised and cell-attached patches of rat and human axons. In rat axons the channels showed an outwardly rectifying current-voltage relationship with a slope conductance of 33 pS at ...
Baker   +19 more
core   +1 more source

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