Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
Phytotherapy Research, EarlyView.By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source
Quercetins, Chlorogenic Acids and Their Colon Metabolites Inhibit Colon Cancer Cell Proliferation at Physiologically Relevant Concentrations. [PDF]
Int J Mol Sci, 2023 Cattivelli A, Conte A, Tagliazucchi D.
europepmc +1 more source
Coloration Technology, EarlyView.Abstract The instability of anthocyanins limits their application as natural food colorants. This study aimed to enhance the stability of anthocyanins extracted from Hibiscus sabdariffa through copigmentation with protein nanofibrils produced from pea, rice, gluten and whey isolates. Linear and curly nanofibril structures were prepared and incorporated
Vildan Eyiz +2 more
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The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases. [PDF]
Molecules, 2023 Murai T, Matsuda S.
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Conjugation of Coffee Phenolics With Milk Bioactive Peptides: Characterization of Coffee and Apple Phenolics and Evaluation of Polyphenol Oxidase as a Natural Biocatalyst. [PDF]
Food Sci NutrGreen coffee beans provided a chlorogenic acid (CQA)‐rich extract, while apple juice served as a natural source of polyphenol oxidase (PPO). The coffee phenolics were characterized by HPLC–MS and combined with milk bioactive peptides, BioZate1 and Glycomacropeptide, under alkaline and PPO‐mediated conditions.
Hamadneh BN +11 more
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The FEBS Journal, EarlyView.In Colletotrichum acutatum species complex, conserved ring‐cleavage dioxygenases located adjacent to AA5_2 enzymes were investigated as potential redox partners. Biochemical analyses identified the dioxygenases as intradiol‐cleaving enzymes preferentially oxidizing methyl‐substituted catechols, while AA5_2 enzymes displayed weak alcohol oxidase ...
Radka Končitíková +7 more
wiley +1 more source
Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in Centella asiatica Extracts That Mediate Resilience to Chronic Stress in Drosophila melanogaster. [PDF]
Nutrients, 2023 Holvoet H +9 more
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International Journal of Cosmetic Science, EarlyView.This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques +6 more
wiley +1 more source
Acta Scientiarum Polonorum: Hortorum Cultus, 2017 The aim of the study was to determine the effect of plant age and growth phase on the accumulation of phenolics in stem bark, leaves and underground organs of Eleuthero. Their content was assessed using validated HPLC-DAD method.
Katarzyna Bączek +3 more
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Hand-Portable Miniaturized Liquid Chromatography for the Determination of Chlorogenic Acids in Dietary Supplements. [PDF]
Antioxidants (Basel), 2022 Soto C +4 more
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