A monoclinic polymorph of chlorothiazide [PDF]
A new polymorph of the diuretic chlorothiazide, 6-chloro-1,1-dioxo-2H-1,2,4-benzothiazine-7-sulfonamide, C7H6ClN3O4S2, is described. Crystallized from basic aqueous solution, this monoclinic polymorph is found to be less thermodynamically favoured than ...
Rowan K. H. Brydson, Alan R. Kennedy
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Chlorothiazide, with the brand name Diuril, is used as a diuretic as well as an antihypertensive drug. This medicine with very slight solubility in water and low permeability is categorized in the class IV of Biopharmaceutical Classification System (BCS)
Mohammed Majrashi +5 more
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Green HPLC strategy for quantification of carvedilol and hydrochlorothiazide in cardiac medications with in-vitro dissolution kinetics and impurity profiling [PDF]
The introduction of new pharmaceutical formulations necessitates the development of a trustworthy analytical approach capable of quantifying active ingredients in various quality control procedures.
Mona Nabil +4 more
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AQbD TLC-densitometric method approach along with green fingerprint and whiteness assessment for quantifying two combined antihypertensive agents and their impurities [PDF]
Preserving the environment, reducing the amount of waste resulting from chemical trials, and reducing the amount of energy consumed have currently become a pivotal global trend.
Hend M. Nagieb +4 more
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COMPLEXES WITH BIOLOGICALLY ACTIVE LIGANDS. Part 3 SYNTHESIS OF COORDINATION COMPOUNDS OF CHLOROTHIAZIDE WITH DIVALENT METAL IONS [PDF]
Supuran, Claudiu T.
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Background/purpose: Chlorothiazide is a well-known diuretic and an antihypertensive drug with poor solubility and permeability and thus low bioavailability.
Ahmad J. Obaidullah
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Diuretic Resistance Treated with Low-Dose Hydralazine: A Case Report and Review of the Literature
We present a case of severe diuretic resistance and edema from acute cardiorenal syndrome complicating heart failure with preserved ejection fraction (HFpEF) and mild alcoholic liver disease.
Mohammed Alshehri, Christopher Wilcox
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Multifunctional crosslinked chitosan/nitrogen-doped graphene quantum dot for wastewater treatment
The fabrication of multifunctional nanomaterial for the adsorption of different types of pollutants is a challenge and could be a solution for many problems associated with wastewater treatment.
Abdelfattah Amari +6 more
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Decongestive diuresis using combination intravenous loop diuretics plus chlorothiazide in type 1 acute cardiorenal syndrome and worsening acute kidney injury; a neglected paradigm in resource-poor settings [PDF]
Over the last decade or more, there has grown a body of evidence demonstrating that renal dysfunction in heart failure is a combination of forward failure from reduced cardiac output and therefore reduced glomerular filtration rate, as well as ...
Macaulay Amechi Chukwukadibia Onuigbo
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