Results 11 to 20 of about 8,069 (212)

Neutropenia Associated With Furosemide Administration in a Preterm Infant. [PDF]

Case Rep Pediatr
Furosemide is a commonly used diuretic, though there is scant literature describing its association with leukopenia. We present a case of neutropenia observed in a preterm infant with a congenital heart anomaly, who received both oral and intravenous furosemide over the course of two hospitalizations. Using the Naranjo adverse drug reaction probability
Connolly GK, Keates-Baleeiro J, Curren V, Brady T, Procaccini D, Coulson JD.   +5 more
europepmc   +2 more sources

On the deprotonation of chlorothiazide. [PDF]

Acta Crystallogr C Struct Chem
The structures of the Na and K salt forms of chlorothiazide have been re‐investigated and are found to have different hydration states and deprotonation sites from those described previously. The structure of the Cs salt form is found to contain the same anion as in the new models for the Na and K salt forms.Three alkali metal salt forms of the ...
Brydson RKH, Gray ML, Kennedy AR, O'Hara BC, Reid MW, Ugbolue I.   +5 more
europepmc   +2 more sources

Efficacy of pharmacologic therapies in patients with acute heart failure: A network meta-analysis

Frontiers in Pharmacology, 2022
Background: A network meta-analysis (NMA) of the current recommended drugs for the treatment of acute heart failure (AHF), was performed to compare the relative efficacy.Methods: We used PubMed, EMBASE, Cochrane Clinical Trials Register, and Web of ...
Hengheng Dai, Haisong Li, Bin Wang, Jingjing Zhang, Ying Chen, Xuecheng Zhang, Yan Liu, Hongcai Shang   +7 more
doaj   +1 more source

Diazoxide-responsive hyperinsulinaemic hypoglycaemia in tyrosinaemia type 1

Endocrinology, Diabetes & Metabolism Case Reports, 2021
Tyrosinaemia type 1 (TT1) is a rare inherited disorder of amino acid metabolism typically presenting with liver failure and renal tubular dysfunction. We describe three individuals with TT1 and transient hyperinsulinaemic hypoglycaemia (HH). Two siblings
Ellada Sotiridou, Henrike Hoermann, Sommayya Aftab, Antonia Dastamani, Eva Thimm, Louise Doodson, Spyros Batzios, Sebastian Kummer, Pratik Shah   +8 more
doaj   +1 more source

Synthesis, Characterization, and Intrinsic Dissolution Studies of Drug–Drug Eutectic Solid Forms of Metformin Hydrochloride and Thiazide Diuretics

Pharmaceutics, 2021
The mechanochemical synthesis of drug–drug solid forms containing metformin hydrochloride (MET·HCl) and thiazide diuretics hydrochlorothiazide (HTZ) or chlorothiazide (CTZ) is reported.
Guadalupe Coyote-Dotor, José C. Páez-Franco, Daniel Canseco-González, Alejandra Núñez-Pineda, Alejandro Dorazco-González, Inés Fuentes-Noriega, Alfredo R. Vilchis-Néstor, Joelis Rodríguez-Hernández, David Morales-Morales, Juan Manuel Germán-Acacio   +9 more
doaj   +1 more source

Transdifferentiation of Integrin Beta 1 High+ Skin Progenitor Cells Into Functional Hepatocytes. [PDF]

Stem Cells Int
A highly reproducible and functional liver model that closely resembles the human liver plays a crucial role in drug development, disease research, personalized medicine, and regenerative medicine. This study aimed to establish an in vitro liver model using skin epidermal progenitor cells (EPCs), which are easily accessible and exhibit a high ...
Lim JH, Kim DH, Lee J, Jung CR, Kang HM.
europepmc   +2 more sources

Pulmonary Hypertension Outcomes After Closure of Atrial Septal Defect in Infants With Developmental Lung Disease. [PDF]

Pulm Circ
ABSTRACT Pulmonary hypertension (PHTN) in infants with developmental lung disease, such as bronchopulmonary dysplasia (BPD), chronic lung disease of infancy (CLD), or congenital diaphragmatic hernia (CDH), can be exacerbated by atrial septal shunts secondary to atrial septal defects (ASD).
Wiegand JL, Thompson JA, Landeck BF, Fierstein JL, Ashour D, Machry JS, Kiskaddon AL, Betensky M, Freire GA.   +8 more
europepmc   +2 more sources

Thiazides in advanced chronic kidney disease—time for a randomized controlled trial? [PDF]

, 2015
Purpose of review: Chronic kidney disease is common, associated with increased cardiovascular risk, and frequently complicated by hypertension, requiring multiple agents for control.
Agarwal, Rajiv, Sinha, Arjun D.
core   +1 more source

Hyponatraemia and hypokalaemia due to indapamide [PDF]

, 2002
The document attached has been archived with permission from the editor of the Medical Journal of Australia (10 January 2008). An external link to the publisher’s copy is included.Objectives: To review Australian adverse drug reaction reports describing ...
Chapman, M., Hanrahan, R., Marley, J., McEwen, J.   +3 more
core   +1 more source

Impact of process variables on the micromeritic and physicochemical properties of spray-dried microparticles, part II: physicochemical characterisation of spray-dried materials [PDF]

, 2012
YesObjectives  In this work we investigated the residual organic solvent content and physicochemical properties of spray-dried chlorothiazide sodium (CTZNa) and potassium (CTZK) salts.
Al-Obaidi, Anne Marie Healy, Burnett, Corrigan, Council of Europe, Dobry, Gil, Gilani, Hancock, Hancock, Harjunen, Holubová, Kim, Krzysztof J. Paluch, Lidia Tajber, Maria I. Amaro, Mollica, Mollica, Nolan, NíÓgáin, Owen I. Corrigan, Paluch, Paluch, Paluch, Quesenberry, Seidell, Tajber, Tajber, Ulvi   +28 more
core   +1 more source