Results 21 to 30 of about 5,666 (226)

Dried blood spots for doping controls—Development of a comprehensive initial testing procedure with fully automated sample preparation

open access: yesBiomedical Chromatography, Volume 37, Issue 8, August 2023., 2023
Abstract Currently, primarily urine, whole blood and serum samples are analyzed for doping‐relevant substances in professional sports, but recently dried blood spots (DBS) have been introduced as complementary matrix, offering advantageous features, e.g. a minimally invasive sampling procedure.
Ann‐Marie Garzinsky   +5 more
wiley   +1 more source

An eco-friendly separation-based framework for quantitative determination and purity testing of an antihypertensive ternary pharmaceutical formulation

open access: yesBMC Chemistry, 2023
Designing new, verified methodologies with a focus on sustainability, analytical efficiency, simplicity, and the environment has become a major priority for pharmaceutical quality control units.
Hoda M. Marzouk   +3 more
doaj   +1 more source

Thiazides in advanced chronic kidney disease—time for a randomized controlled trial? [PDF]

open access: yes, 2015
Purpose of review: Chronic kidney disease is common, associated with increased cardiovascular risk, and frequently complicated by hypertension, requiring multiple agents for control.
Agarwal, Rajiv, Sinha, Arjun D.
core   +1 more source

Retrospective analysis of SGLT2 inhibitors in heart failure with preserved ejection fraction

open access: yesESC Heart Failure, Volume 10, Issue 3, Page 2010-2018, June 2023., 2023
Abstract Aims Heart failure (HF) is one of the leading causes of cardiovascular morbidity and mortality. HF with preserved ejection fraction (HFpEF), or diastolic failure, accounts for half of all HF cases and differs from HF with reduced ejection fraction (HFrEF).
John S. Clemmer   +2 more
wiley   +1 more source

Study of factors which modify the development of norepinephrine-induced acute renal failure in the dog [PDF]

open access: yes, 1979
Study of factors which modify the development of norepinephrine-induced acute renal failure in the dog. Previous studies have demonstrated that the fall in inulin clearance which occurs 3 hours after the intrarenal administration of norepinephrine can be
Fadem, Stephen Z.   +3 more
core   +1 more source

Recent progress in orodispersible films‐mediated therapeutic applications: A review

open access: yesMedComm – Biomaterials and Applications, Volume 2, Issue 2, June 2023., 2023
The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract Orodispersible ...
Yu Tian   +5 more
wiley   +1 more source

Acute effect of prednisolone on renal handling of sodium. [PDF]

open access: yes, 1973
The effect of prednisolone on renal handling of sodium (Na) was studied in rats under three experimental conditions: 1) hydropenia, 2) water diuresis, and 3) distal tubular blockade (DTB).
Halgrimson, CG   +3 more
core   +1 more source

What did the scientific literature learn from internal company documents in the pharmaceutical industry? A scoping review

open access: yesCochrane Evidence Synthesis and Methods, Volume 1, Issue 3, May 2023., 2023
Abstract Objective To identify all scientific papers that used internal industry documents in the pharmaceutical sector and analyze what and how the scientific literature learned about corporate influence in the pharmaceutical sector through these internal documents. Design Scoping review.
Marc‐André Gagnon, Miaoran Dong
wiley   +1 more source

Mechanisms of Diuretic Resistance Study: design and rationale

open access: yesESC Heart Failure, 2020
Introduction Diuretic resistance is a common complication impairing decongestion during hospitalization for acute decompensated heart failure (ADHF). The current understanding of diuretic resistance mechanisms in ADHF is based upon extrapolations from ...
Zachary L. Cox   +10 more
doaj   +1 more source

Sustainable chromatographic quantitation of multi-antihypertensive medications: application on diverse combinations containing hydrochlorothiazide along with LC–MS/MS profiling of potential impurities: greenness and whiteness evaluation

open access: yesBMC Chemistry, 2023
Cardiovascular disorders are among the leading causes of death worldwide, especially hypertension, a silent killer syndrome requiring multiple drug therapy for appropriate management.
Hoda M. Marzouk   +5 more
doaj   +1 more source

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