Results 101 to 110 of about 51,092 (216)

Evaluation of Potentially Inappropriate Medications Prescribed to Older Adults Upon Emergency Department Discharge

Academic Emergency Medicine, Volume 33, Issue 3, March 2026.
ABSTRACT Background Older adults are susceptible to adverse drug effects due to age‐related changes, a higher prevalence of comorbidities, and complexities in medication management. Nearly half of geriatric patients are prescribed at least one new medication at ED discharge.
Jessica Schowe, Andrew M. North, Kyle Schuchter, Katherine M. Hunold, Elizabeth Rozycki   +4 more
wiley   +1 more source

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

Cell Proliferation, Volume 59, Issue 3, March 2026.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao, Yuhan Qiu, Xiaowei Wang, Mengyan Wang, Li Liu, Xiaojun Zhao, Zixiang Gao, Rongguang Shao, Guimin Xia, Wuli Zhao   +9 more
wiley   +1 more source

Impact of CYP2D6 Metabolizer Status on Ondansetron Efficacy in Early Pregnancy Induced Nausea and Vomiting: A Case Control Study

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Real‐world data investigating CYP2D6 on the efficacy of ondansetron for nausea and vomiting in pregnancy (NVP) is lacking. Evidence shows CYP2D6 ultrarapid metabolizers are at risk of ondansetron nonresponse due to increased metabolism. We conducted a retrospective cohort study of early pregnant patients on ondansetron for NVP.
Michelle Liu, Megan M. Shuey, Sabrina E. Holley, Darlene F. Fountain, James Jaworski, Carol Griffin, Jeewoo Kim, Melissa Stec, Sudeep D. Sunthankar, Henry H. Ong, Srushti Gangireddy, Wei‐Qi Wei, Andrea Gaedigk, Digna R. Velez Edwards, Vivian K. Kawai   +14 more
wiley   +1 more source

Proteasome localization and activity in pig brain and in vivo small molecule screening for activators

Frontiers in Cellular Neuroscience
IntroductionLoss of proteasome function, proteinopathy, and proteotoxicity may cause neurodegeneration across the human lifespan in several forms of brain injury and disease.
Adriana Amrein Almira, May W. Chen, Nagat El Demerdash, Cameron Javdan, Dongseok Park, Jennifer K. Lee, Lee J. Martin, Lee J. Martin, Lee J. Martin, Lee J. Martin   +9 more
doaj   +1 more source

Chlorpromazine

International Journal of Clinical Practice, 1956
openaire   +4 more sources

Chlorpromazine Jaundice [PDF]

BMJ, 1957
openaire   +2 more sources

Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar

Neuropsychopharmacology Reports
Aims Women may experience unique mental disorders due to hormone shifts. Rates of schizophrenia and bipolar disorder are similar between genders, but onset and symptoms may differ.
Nervana Elbakary, Oraib Abdallah, Sami Ouanes, Ahmad Hasanoglu, Eiman Abedlfattah‐Arafa, Maha Al‐Shaikhly, Shatha Alqam, Sulaiman Alshakhs, Zainab Hijawi, Majid Al‐Abdulla, Noriya Al‐Khuzaei, Sazgar Hamad   +11 more
doaj   +1 more source

Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine

Proceedings of the National Academy of Sciences of the United States of America, 2016
Mieke Nys, E. Wijckmans, A. Farinha, Özge Yoluk, M. Andersson, M. Brams, R. Spurny, S. Peigneur, J. Tytgat, E. Lindahl, C. Ulens   +10 more
semanticscholar   +1 more source

Chlorpromazine versus placebo for schizophrenia.

Cochrane Database of Systematic Reviews, 2014
Clive E Adams, G. Awad, J. Rathbone, B. Thornley, K. Soares-Weiser   +4 more
semanticscholar   +1 more source

Clinical predictors of short-term treatment response in stupor: a retrospective study. [PDF]

Front Psychiatry
Zong X, Liu Z, Yang Z, Zhang C, Li R, Li K, Li B.   +6 more
europepmc   +1 more source