Results 101 to 110 of about 82,153 (289)
MALT1 proteolytic activity suppresses autoimmunity in a T cell intrinsic manner [PDF]
, 2019 MALT1 is a central signaling component in innate and adaptive immunity by regulating NF-kappa B and other key signaling pathways in different cell types. Activities of MALT1 are mediated by its scaffold and protease functions.
Baens, Mathijs +7 more
core +2 more sources
Clinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan +7 more
wiley +1 more source
Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations [PDF]
, 1992 We measured the permeability ratios (PX/PNa) of 3 wild-type, 1 hybrid, 2 subunit-deficient, and 22 mutant nicotinic receptors expressed in Xenopus oocytes for alkali metal and organic cations using shifts in the bi-ionic reversal potential of the ...
Cohen, Bruce N. +3 more
core
Drug Points: Apparent interaction between warfarin and levonorgestrel used for emergency contraception [PDF]
, 2000 No abstract ...
Ellison, J. +3 more
core +2 more sources
Chlorpromazine-Induced Severe Hyponatremia in 66 Years Old Patient
Acta Medica Indonesiana, 2023 Hyponatremia is a common clinical problem in older people. The aging process is usually accompanied by various maladaptations to stress in different organs and physiologic functions.
Sri Soenarti, Muchammad Kamal Hadi
doaj
Antigenicity of chlorpromazine and clozapine to rabbits [PDF]
, 1970 Antigenicity of clozapine was studied in rabbits, comparing with that of chlorpromazine as control. The results indicate that chlorpromazine produces antibody in rabbit as revealed by passive hemagglutination test, giving the titer of 1 : 2, 000 or ...
Seno, Satimaru +2 more
core +1 more source
Nuclear Control of Mitochondrial Homeostasis and Venetoclax Efficacy in AML via COX4I1
Advanced ScienceCell signaling pathways are enriched for biological processes crucial for cellular communication, response to external stimuli, and metabolism. Here, a cell signaling‐focused CRISPR screen identified cytochrome c oxidase subunit 4 isoform 1 (COX4I1) as a
Leisi Zhang +19 more
doaj +1 more source
Effects of LHRH-A2 and chlorpromazine (dopamine antagonists) on inducing spawning in Caspian Kutum, Rutilus frisii kutum, from the southwest of the Caspian Sea [PDF]
, 2012 Caspian kutum, Rutilus frisii kutum, is one of the most commercially important fish species in the Caspian Sea, but there are few reports about the endocrinology of induced spawning in this fish. In the present study, 54 individuals of female broodstocks
Ahmadnezhad, M. +4 more
core +1 more source
Neuropsychiatric Disease and Treatment, 2018 Kumi Sakurada,1,* Takeshi Kozaru,2,* Kazuo Yamada,1 Masashi Nibuya,1 Kiyoshi Nagata,3 Eiji Suzuki1 1Department of Psychiatry, 2Department of Dermatology, 3Department of Environmental and Health Science, Tohoku Medical and Pharmaceutical University ...
Sakurada K +5 more
doaj
Psychiatry and Clinical Psychopharmacology, 2021 Objective: Effects of chlorpromazine and haloperidol on erythrocyte glucose 6-phosphate dehydrogenase enzyme activity were investigated in invitro conditions. Methods: Glucose 6- phosphate dehydrogenase was purified from human erythrocyte.
Mehmet Emin Büyükokuroğlu +4 more
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