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Proposal for a Council Directive concerning the placing of EEC-accepted plant protection products on the market. COM (76) 427 final, 20 July 1976 [PDF]

, 1976

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Biodegradation of α-solanine and α-chaconine: Insights into microbial detoxification and enzymatic deglycosylation pathways. [PDF]

Food Chem X
Wei Z, Wang H, Zhong R, Chen L, Vigors S, Zhang H.   +5 more
europepmc   +1 more source

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Developmental toxicity of chlorpropham in mice

Reproductive Toxicology, 1997
The present studies were designed to evaluate the developmental toxicity of chlorpropham in mice. The first study was conducted to determine administration time, and the second study was designed to evaluate dose-response effects. Chlorpropham was administered to pregnant mice by gavage on Days 8, 8.3, 9, 9.3, 10, and 11 of gestation at a level of 3000
Toyohito Tanaka, T Fujitani, S Oishi
exaly   +3 more sources

Effects of chlorpropham (CIPC) on the hemopoietic system of rats

Food and Chemical Toxicology, 2001
Male F344 rats were given 0 or 3% chlorpropham in the diet and at 2, 4, 6, 8 or 13 weeks of administration, five rats in each group were examined for hematology, plasma clinical chemistry and pathology. Marked splenomegaly and hepatomegaly were observed in treated rats at 2-13 weeks of administration.
T Fujitani
exaly   +3 more sources

Chlorpropham-induced splenotoxicity and its recovery in rats

Food and Chemical Toxicology, 2004
To determine the reversibility of hematological and pathological changes in spleen induced by sub-chronic administration of chlorpropham (CIPC), male F344 rats were given CIPC in the diet at 0, 600, 3000 or 15,000 ppm for 13 weeks (administration period) and then were given standard (0 ppm) diet for 10 weeks (recovery period). At 0, 1, 2, 4 or 10 weeks
T Fujitani
exaly   +3 more sources

Level and fate of chlorpropham in potatoes during storage and processing

Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes, 2008
Chlorpropham (isopropyl 3-chlorocarbanilate) is a pesticide used to control sprouting of potatoes during long-term storage. The objective of the present study was to establish the total chlorpropham residue balance (residues in unwashed and washed whole tubers, peeled tubers, peels, boiled and pureed tubers, and washing and cooking waters) for two ...
William C Koskinen
exaly   +3 more sources

Fate of Chlorpropham during High-Temperature Processing of Potatoes

Journal of Agricultural and Food Chemistry, 2020
Chlorpropham is a widely used sprouting inhibitor applied on potatoes during their storage. Currently, severe concerns are raised regarding the potential formation of 3-chloroaniline from chlorpropham during heat treatment. The reactions degrading the molecule in the matrix are quite complex under harsh processing conditions, and a molecular ...
Bernd Göckener
exaly   +3 more sources

Reproductive and neurobehavioural toxicity study of chlorpropham in mice

Food Additives and Contaminants, 1999
Chlorpropham was given in the diet to provide levels of 0 (control), 500, 1,000, and 2,000 mg/kg from 5 weeks of age of the F0 generation to 9 weeks of age of the F1 generation in mice, and selected reproductive and neurobehavioural parameters were measured.
Toyohito Tanaka
exaly   +3 more sources

Toxicokinetics, metabolism, and microsomal studies of chlorpropham in rats

Toxicological and Environmental Chemistry, 2006
A study on the toxicokinetic behavior, metabolism of chlorpropham, and its effect on cytochrome P450 from liver microsomes was carried out in albino rats after a single and consecutive oral administration at 500 mg kg−1 body weight for 10 and 20 days.
Shyamal Kumar Das, Tapan Kumar Mandal
exaly   +2 more sources

Interaction of hexachlorocyclohexane (HCH) and chlorpropham (CIPC) in male rats

Toxicology Letters, 1989
Hexachlorocyclohexane (60.0 mg/kg/d) and chlorpropham (50.0 mg/kg/d) given to male rats daily orally for 30 d caused subtle biochemical lesions. The significant rise in the activity of alkaline phosphatase in liver and serum and of GOT and GPT in liver with substantial weight increase of liver has been suggestive of the initiation of biochemical ...
T S S Dikshith, G Carrera, R B Raizada   +2 more
exaly   +3 more sources