Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by Chlorthalidone [PDF]
Purpose. To report two persons with acute, bilateral, and simultaneous angle closure glaucoma in pseudophakia secondary to uveal effusions induced by administration of chlorthalidone. Methods. Case reports. Results.
Indra Durai +4 more
doaj +2 more sources
Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease [PDF]
OBJETIVE: Antihypertensive therapy with thiazides decreases coronary events in elderly patients. However, the influence of diuretics on myocardial ischemia has not been fully investigated. The aim of this study was to compare the effect of chlorthalidone
João Batista Serro-Azul +9 more
doaj +2 more sources
Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone [PDF]
The article analyzes data from clinical studies on the efficacy and safety of azilsartan medoxomil/chlorthalidone combination and its components. According to the analyzed sources, both individual components and their combination have proven their ...
M. D. Smirnova +2 more
doaj +2 more sources
Drug-induced acute myopia following chlorthalidone treatment
We report a case of sudden loss of vision due to the development of acute myopia after the intake of chlorthalidone used for treating systemic hypertension.
Mahesh G +3 more
doaj +1 more source
Efficacy and Safety of a Single-Pill Triple Combination of Valsartan, Amlodipine, and Chlorthalidone in Patients With Essential Hypertension Inadequately Controlled on Dual Therapy With Valsartan and Amlodipine: A Randomized, Double-Blind, Multicenter, Phase 3 Trial. [PDF]
ABSTRACT Many hypertensive patients require three or more antihypertensive agents to achieve target blood pressure. This randomized, double‐blind, multicenter phase 3 trial conducted in South Korea evaluated the efficacy and safety of a single‐pill triple combination therapy with valsartan (Val), amlodipine (Aml), and chlorthalidone (CTD) in patients ...
Cho IJ +10 more
europepmc +2 more sources
Exploring Risks of Adverse Drug Events From Single Drug to Three-Drug Combination. [PDF]
ABSTRACT Use of three‐drug combinations is common and could increase the risk of adverse drug events (ADEs). Signals of ADEs from three‐drug combinations could be identified from real‐world data, and the risks of ADEs from single drug exposure to three‐drug combination exposure could be illustrated by a graphic model.
Shi Y +14 more
europepmc +2 more sources
Severe Hypokalemia With Rhabdomyolysis-A Case Report. [PDF]
ABSTRACT Magnesium administration should be considered in severe or refractory hypokalemia with even normal serum magnesium; however, more research is needed to establish the evidence and take into account confounding factors. Severe hypokalemia can manifest with rhabdomyolysis, which can affect kidney function.
Shahzad T, Murray A.
europepmc +2 more sources
Background Chlorthalidone is a diuretic medicinal agent used to treat hypertension. Lowering hypertension results in the prevention of strokes, heart attacks and kidney-related problems.
Suraj R. Chaudhari, Atul A. Shirkhedkar
doaj +1 more source
The use of diuretics in arterial hypertension is pathogenetically justified, which is due to the significant role of an increase in the volume of circulating blood and the retention of sodium ions in the internal environment of the body, in increasing ...
Dmitry I. Trukhan +1 more
doaj +1 more source
Comparative efficacy and safety of chlorthalidone <i>vs</i> hydrochlorothiazide in hypertension management: A systematic review and meta-analysis. [PDF]
BACKGROUND: Hypertension is among the leading causes of cardiovascular diseases, including myocardial infarction (MI), stroke, and heart failure. The thiazide diuretics of chlorthalidone and hydrochlorothiazide are commonly prescribed in the control of ...
Kumari U +6 more
europepmc +2 more sources

