Results 21 to 30 of about 4,532 (203)

All diuretics used in the treatment of hypertension are not the same

Türk Kardiyoloji Derneği Arşivi, 2017
Summary– Diuretics have been used for years to treat hypertension as both a monotherapy and in combination. Hydrochlorothiazide, indapamide, and chlorthalidone have frequently been considered in the same category as thiazide diuretics, but there is no ...
Serkan Asil, Enver Atalar
doaj   +1 more source

Endothelin Receptor Antagonists in Resistant Hypertension and Proteinuric Kidney Disease: Receptor Strategy and Volume Management. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT This narrative review examines how endothelin receptor antagonists (ERAs) can be used at the intersection of difficult‐to‐control hypertension, chronic kidney disease (CKD), and albuminuria or proteinuria. For clinicians, the central question is not receptor selectivity alone, but whether a specific agent, indication, dose, background therapy,
Goldman CK, Goldman JM.
europepmc   +2 more sources

A randomized trial of the efficacy and safety of azilsartan medoxomil combined with chlorthalidone [PDF]

, 2018
INTRODUCTION: We measured the effects of azilsartan medoxomil co-administered with chlorthalidone 25 mg in stage 2 hypertension. METHODS: Azilsartan medoxomil 40 or 80 mg plus chlorthalidone were compared with placebo plus chlorthalidone once daily in a ...
Sever, Peter, Cao, Charlie, Roberts, Andrew, Juhasz, Attila, Weber, Michael A   +4 more
core   +1 more source

Efficacy and safety of standard dose triple combination of telmisartan 80 mg/amlodipine 5 mg/chlorthalidone 25 mg in primary hypertension: A randomized, double‐blind, active‐controlled, multicenter phase 3 trial

The Journal of Clinical Hypertension, 2023
The authors evaluated the efficacy, safety, and characteristics of patients who respond well to standard dose triple combination therapy including chlorthalidone 25 mg with telmisartan 80 mg plus amlodipine 5 mg in hypertensive patients.
Eun Joo Cho, Moo Hyun Kim, Young‐Hak Kim, Kiyuk Chang, Dong‐Ju Choi, Woong Chol Kang, Jinho Shin, Seong Hwan Kim, Namho Lee, Jang Won Son, Joon‐Hyung Doh, Woo‐Shik Kim, Soon Jun Hong, Moo‐Yong Rhee, Youngkeun Ahn, Sang‐Wook Lim, Seung Pyo Hong, So‐Yeon Choi, Min Su Hyon, Jin‐Yong Hwang, Kihwan Kwon, Kwang Soo Cha, Sang‐Hyun Ihm, Jae‐Hwan Lee, Byung‐Su Yoo, Hyo‐Soo Kim   +25 more
doaj   +1 more source

Environmental benign RP-HPLC method for the simultaneous estimation of anti-hypertensive drugs using analytical quality by design

Green Chemistry Letters and Reviews, 2023
Green analytical procedures replace harmful organic modifiers with green solvents without affecting chromatographic performance, enabling industries and research laboratories to develop green analytical methods.
Naveenarani Dharuman, Karunanidhi Santhana Lakshmi, Manikandan Krishnan   +2 more
doaj   +1 more source

Chlorthalidone promotes mineral retention in patients with idiopathic hypercalciuria [PDF]

, 1988
Chlorthalidone promotes mineral retention in patients with idiopathic hypercalciuria. In seven patients with severe idiopathic hypercalciuria and recurrent calcium oxalate nephrolithiasis, we have determined the effects on mineral balance of chronic ...
Bushinsky, David A., Coe, Fredric L., Langman, Craig B., Parks, Joan H., Favus, Murray J.   +4 more
core   +1 more source

Chlorthalidone vs Hydrochlorothiazide for Hypertension-CV Events: Did the Design Influence the Outcome?

, 2023
The Diuretic Comparison Project (DCP)1 was a real world study planned to evaluate in a pragmatic manner whether Chlorthalidone (CTD), as compared with Hydrochlorothiazide (HCTZ), would reduce the risk of major nonfatal cardiovascular disease outcomes in ...
Ram, C Venkata S, Pareek, Anil, Messerli, Franz H   +2 more
core   +1 more source

Antihypertensive efficacy of metoprolol XL/Low dose chlorthalidone (6.25 mg) combination: a randomized, comparative study in Indian patients with mild-to-moderate essential hypertension

European Journal of Medical Research, 2009
Objective High blood pressure is one of the most important risk factors, directly responsible for increasing the cardiovascular morbidity and mortality. The primary objective was to evaluate the efficacy of metoprolol XL/chlorthalidone against metoprolol
Pareek A, Zawar SD, Salagre SB, Chandurkar NB, Karnik ND   +4 more
doaj   +1 more source

Preferred Diuretic Therapy in Primary Hypertension: Chlorthalidone or Hydrochlorothiazide?

, 2023
Chlorthalidone is recommended as the preferred diuretic therapy for primary hypertension. However, results from multiple studies suggest an equivalent response when compared to hydrochlorothiazide.
Young, Trevor
core   +1 more source

Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease

, 2021
BACKGROUND: Little evidence has been available to support the use of thiazide diuretics to treat hypertension in patients with advanced chronic kidney disease.
Sinha, Arjun D., Tu, Wanzhu, Cramer, Andrew E., Dickinson, Jazmyn H., Agarwal, Rajiv, Balmes-Fenwick, Mary, Ouyang, Fangqian   +6 more
core   +1 more source