Results 21 to 30 of about 214 (128)

Comparative Efficacy of Single Pill Combinations of Azilsartan Medoxomil/Chlorthalidone and Losartan/Hydrochlorothiazide in Patients with Hypertension and Heart Failure with Preserved Ejection Fraction

Рациональная фармакотерапия в кардиологии, 2022
Aim. To study the effects of azilsartan medoxomil/chlorthalidone (AZM/CTD) and losartan/hydrochlorothiazide (LOS/HCT) combinations for NTproBNP levels, 6-minute walk test results, hydration status along with their antihypertensive efficacy according to ...
Zh. D. Kobalava, A. F. Safarova, Kh. M. Gudieva, M. A. Markova, A. E. Petrosyan   +4 more
doaj   +1 more source

Optimized and Validated RP-UPLC Method for the Determination of Losartan Potassium and Chlorthalidone in Pharmaceutical Formulations [PDF]

Advanced Pharmaceutical Bulletin, 2015
Purpose: A validated ultra performance liquid chromatography (UPLC) method has been developed and validated for the simultaneous determination of losartan potassium and chlorthalidone in pharmaceutical preparations.
Tadiboyina Sirisha, Bannimath Gurupadayya, Sridhar Siddiraju   +2 more
doaj   +1 more source

Per‐Protocol Analysis of Chlorthalidone Versus Hydrochlorothiazide for Cardiovascular Event Prevention—Diuretic Comparison Project

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The DCP (Diuretic Comparison Project), a pragmatic trial, evaluated whether chlorthalidone compared with hydrochlorothiazide would reduce the risk of nonfatal cardiovascular disease or noncancer‐related death.
Sonia T. Anand, Cynthia Hau, Michael J. Davenport, Areef Ishani, William C. Cushman, Peter A. Glassman, Addison A. Taylor, Robert A. Lew, Ryan E. Ferguson, Sarah M. Leatherman   +9 more
doaj   +1 more source

Risk of hospitalized and non-hospitalized gastrointestinal bleeding in ALLHAT trial participants receiving diuretic, ACE-inhibitor, or calcium-channel blocker.

PLoS ONE, 2021
ObjectivesThis post-trial data linkage analysis was to utilize the data of Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) participants linked with their Medicare data to examine the risk of hospitalized and non ...
Xianglin L Du, Lara M Simpson, Brian C Tandy, Judith L Bettencourt, Barry R Davis   +4 more
doaj   +2 more sources

Atrial High‐Rate Episodes Mirror Atrial Fibrillation in Stroke Prediction: Evidence From an Indian Prospective Cohort

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
This prospective matched cohort study, which generates hypotheses, finds that device‐detected AF lasting under 24 h is linked to a notably increased risk of stroke/TIA and progression to clinical AF among Indian patients. ABSTRACT Aims To assess the risk of stroke/TIA and progression to atrial fibrillation (AF) in Indian patients with device‐detected ...
Sedhupathi Shanmugam, Sreevilasam P. Abhilash, Jyothi Vijay, Sapna erat Sreedharan, Narayanan Namboodiri   +4 more
wiley   +1 more source

Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone

Российский кардиологический журнал
The article analyzes data from clinical studies on the efficacy and safety of azilsartan medoxomil/chlorthalidone combination and its components. According to the analyzed sources, both individual components and their combination have proven their ...
M. D. Smirnova, T. V. Fofanova, F. T. Ageyev   +2 more
doaj   +1 more source

Exploring Risks of Adverse Drug Events From Single Drug to Three‐Drug Combination

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Use of three‐drug combinations is common and could increase the risk of adverse drug events (ADEs). Signals of ADEs from three‐drug combinations could be identified from real‐world data, and the risks of ADEs from single drug exposure to three‐drug combination exposure could be illustrated by a graphic model.
Yi Shi, Anna Sun, Chien‐Wei Chiang, Yuedi Yang, Katherine M. Hunold, Jing Xu, Mu Shan, Allison Lu, Massimiliano Russo, Jeffrey M. Caterino, Michael T. Eadon, Lang Li, Jing Su, Macarius Donneyong, Pengyue Zhang   +14 more
wiley   +1 more source

Low-Dose Triple Antihypertensive Combination Therapy in Patients with Hypertension: A Randomized, Double-Blind, Phase II Study

Drug Design, Development and Therapy, 2020
Soon Jun Hong,1,* Ki-Chul Sung,2,* Sang-Wook Lim,3 Seok-Yeon Kim,4 Weon Kim,5 Jinho Shin,6 Sungha Park,7 Hae-Young Kim,8 Moo-Yong Rhee9,10 On behalf of MH_APOLLO to read: HM_APOLLO1Department of Cardiology, Cardiovascular Center, Korea University Anam ...
Hong SJ, Sung KC, Lim SW, Kim SY, Kim W, Shin J, Park S, Kim HY, Rhee MY   +8 more
doaj  

Evaluation of a Point‐of‐Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus)

Journal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Introduction Bonobos (Pan paniscus) are endangered and uncommon in managed care. Prothrombotic and hypofibrinolytic states are encountered with cardiovascular disease, ischemic stroke, and neoplasia. Materials and Methods Twelve bonobos from one institution were evaluated during anesthetized exams.
Megan M. Roeder, Priya Bapodra‐Villaverde, Lauren E. Mumm, Alex M. Lynch, Laura R. Culbreth, Megan L. Cabot, Timothy A. Georoff, Larry J. Minter   +7 more
wiley   +1 more source

DIURETIC-BASED COMBINATION THERAPY IN PATIENTS WITH ARTERIAL HYPERTENSION: RESULTS OF THE RUSSIAN TRUST STUDY

Кардиоваскулярная терапия и профилактика, 2013
Arterial hypertension (AH) is one of the most important problems of the modern medicine, due to its exceptionally high prevalence. This study focused on effectiveness and safety of the diuretic-based combination therapy among patients aged >18 years ...
N. E. Gavrilova, R. G. Oganov
doaj   +1 more source