Results 31 to 40 of about 6,631 (200)

Pharmacogenomic studies of hypertension: paving the way for personalized antihypertensive treatment [PDF]

open access: yes, 2018
Introduction: Increasing clinical evidence supports the implementation of genotyping for anti-hypertensive drug dosing and selection. Despite robust evidence gleaned from clinical trials, the translation of genotype guided therapy into clinical ...
Chapman, Arlene B.   +2 more
core   +1 more source

Comparative Efficacy of Single Pill Combinations of Azilsartan Medoxomil/Chlorthalidone and Losartan/Hydrochlorothiazide in Patients with Hypertension and Heart Failure with Preserved Ejection Fraction

open access: yesРациональная фармакотерапия в кардиологии, 2022
Aim. To study the effects of azilsartan medoxomil/chlorthalidone (AZM/CTD) and losartan/hydrochlorothiazide (LOS/HCT) combinations for NTproBNP levels, 6-minute walk test results, hydration status along with their antihypertensive efficacy according to ...
Zh. D. Kobalava   +4 more
doaj   +1 more source

Hypertension Treatment for Patients with Advanced Chronic Kidney Disease [PDF]

open access: yes, 2014
Chronic kidney disease is common and frequently complicated with hypertension. As a major modifiable risk factor for cardiovascular disease in this high risk population, treatment of hypertension in chronic kidney disease is of paramount importance.
Agarwal, Rajiv, Sinha, Arjun D.
core   +1 more source

S-amlodipine plus chlorthalidone vs. S-amlodipine plus telmisartan in hypertensive patients unresponsive to amlodipine monotherapy: study protocol for a randomized controlled trial

open access: yesTrials, 2018
Background The efficacy of a combination of a calcium channel blocker (CCB) plus chlorthalidone (diuretic) versus a CCB plus an angiotensin receptor blocker (ARB) in patients not responding to CCB monotherapy has not been evaluated previously. We plan to
Sang-Ho Jo   +10 more
doaj   +1 more source

Optimized and Validated RP-UPLC Method for the Determination of Losartan Potassium and Chlorthalidone in Pharmaceutical Formulations [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Purpose: A validated ultra performance liquid chromatography (UPLC) method has been developed and validated for the simultaneous determination of losartan potassium and chlorthalidone in pharmaceutical preparations.
Tadiboyina Sirisha   +2 more
doaj   +1 more source

Severe hyponatremia in older patients at admission in an internal medicine department [PDF]

open access: yes, 2014
Hyponatremia is common in older people, most often of multifactorial origin, and can be associated with poor clinical outcomes. The aim was to analyze the frequency of severe hyponatremia (sodium concentration below 125 mmol/L), risk factors and ...
Carda, José   +8 more
core   +1 more source

Per‐Protocol Analysis of Chlorthalidone Versus Hydrochlorothiazide for Cardiovascular Event Prevention—Diuretic Comparison Project

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The DCP (Diuretic Comparison Project), a pragmatic trial, evaluated whether chlorthalidone compared with hydrochlorothiazide would reduce the risk of nonfatal cardiovascular disease or noncancer‐related death.
Sonia T. Anand   +9 more
doaj   +1 more source

Hypertension [PDF]

open access: yes, 2004
Hypertension is a rapidly moving clinical field with frequent developments in new pharmacologic agents and management strategies. Perhaps more importantly, there have been substantial improvements in our understanding of how best to use the drugs ...
Farrugia, Emanuel
core  

The usefulness of information on HDL-cholesterol: potential pitfalls of conventional assumptions [PDF]

open access: yes, 2001
Treatment decisions related to disease prevention are often based on two conventional and related assumptions. First, an intervention-induced change in a surrogate marker (such as high-density lipoprotein [HDL]-cholesterol) in the desired direction ...
Furberg Curt D
core   +2 more sources

Risk of hospitalized and non-hospitalized gastrointestinal bleeding in ALLHAT trial participants receiving diuretic, ACE-inhibitor, or calcium-channel blocker

open access: yesPLoS ONE, 2021
Objectives This post-trial data linkage analysis was to utilize the data of Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) participants linked with their Medicare data to examine the risk of hospitalized and non ...
Xianglin L. Du   +4 more
doaj   +2 more sources

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