Results 41 to 50 of about 6,631 (200)

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone

open access: yesРоссийский кардиологический журнал
The article analyzes data from clinical studies on the efficacy and safety of azilsartan medoxomil/chlorthalidone combination and its components. According to the analyzed sources, both individual components and their combination have proven their ...
M. D. Smirnova   +2 more
doaj   +1 more source

Modifiable Risk Factors in Atrial Fibrillation: Clinical Implications and Pathophysiological Insights

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 2, March 2026.
Modifiable cardiometabolic and lifestyle factors converge on shared atrial mechanisms, including fibrosis, autonomic imbalance, and electrical remodeling, to promote AF initiation and recurrence. Targeting these upstream drivers through structured risk‐factor management enhances rhythm‐control durability and improves long‐term clinical outcomes ...
Chamath Jagoda
wiley   +1 more source

Low-Dose Triple Antihypertensive Combination Therapy in Patients with Hypertension: A Randomized, Double-Blind, Phase II Study

open access: yesDrug Design, Development and Therapy, 2020
Soon Jun Hong,1,* Ki-Chul Sung,2,* Sang-Wook Lim,3 Seok-Yeon Kim,4 Weon Kim,5 Jinho Shin,6 Sungha Park,7 Hae-Young Kim,8 Moo-Yong Rhee9,10 On behalf of MH_APOLLO to read: HM_APOLLO1Department of Cardiology, Cardiovascular Center, Korea University Anam ...
Hong SJ   +8 more
doaj  

Changes in kidney function in a population with essential hypertension in real life settings [PDF]

open access: yes, 2017
Introduction. Hypertension has been identified as one of the commonest modifiable determinants for chronic kidney disease progression. A variety of antihypertensive drugs are available and their effect on kidney function has been investigated by a ...
Haidich, Anna-Bettina   +6 more
core  

Controlling Selectivity at the First Hydrogenation Level: Synthesis of 3‐Hydroxyisoindolines by Heterogeneously Silver‐Catalyzed Monohydrogenation of Phthalimides

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
3‐Hydroxylactams are obtained from phthalimides through a heterogeneous catalyzed chemoselective hydrogenation, able to stop the process at the first hydrogenation level. By using a rationally designed [Ag/Al2O3] recyclable solid nanocatalyst, a wide range of cyclic hemiamidals are accesed through a full atom‐economical reaction that preserves (hetero ...
Carles Lluna‐Galán   +2 more
wiley   +1 more source

Full spectrum and genetic algorithm-selected spectrum-based chemometric methods for simultaneous determination of azilsartan medoxomil, chlorthalidone, and azilsartan: Development, validation, and application on commercial dosage form

open access: yesOpen Chemistry, 2021
Five various chemometric methods were established for the simultaneous determination of azilsartan medoxomil (AZM) and chlorthalidone in the presence of azilsartan which is the core impurity of AZM.
Darwish Hany W.   +5 more
doaj   +1 more source

Fixed combinations in the management of hypertension: Patient perspectives and rationale for development and utility of the olmesartan – amlodipine combination [PDF]

open access: yes, 2008
Although the awareness and control of hypertension has increased, only 37% of hypertensive patients in the US achieve the conservative goal ...
Pimenta, Eduardo, Oparil, Suzanne
core   +2 more sources

Effectiveness and safety of combining thiazides with loop diuretics vs. loop diuretics monotherapy in patients with acute decompensated heart failure: A retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 220-229, January 2026.
Aims This study investigated factors associated with and outcomes of combined loop diuretics with hydrochlorothiazide (HCTZ) for acute decompensated heart failure (ADHF). Methods In this retrospective study, adults hospitalized for ADHF and who received intravenous loop diuretics between January 2016 and March 2023 were enrolled.
Chia‐Chen Hsu   +6 more
wiley   +1 more source

Insufficient control of blood pressure and incident diabetes [PDF]

open access: yes, 2009
OBJECTIVE: Incidence of type 2 diabetes might be associated with preexisting hypertension. There is no information on whether incident diabetes is predicted by blood pressure control.
CHINALI, MARCELLO   +8 more
core   +2 more sources

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