Results 21 to 30 of about 11,449,307 (399)
Towards Tumor Targeting via Invasive Assay Using Magnetospirillum magneticum
Frontiers in Microbiology, 2021 Magnetospirillum magneticum (AMB-1) are a species of magnetotactic bacteria (MTB) that are capable of orienting along the earth’s magnetic field lines through their organelles called magnetosomes.
Marvin Xavierselvan +4 more
doaj +1 more source
Separation of CHO cells using hydrocyclones [PDF]
Cytotechnology, 2007 Hydrocyclones are simple and robust separation devices with no moving parts. In the past few years, their use in animal cell separation has been proposed. In this work, the use of different hydrocyclone configurations for Chinese hamster ovary (CHO) cell separation was investigated following an experimental design.
Leda R. Castilho +2 more
openaire +3 more sources
Plasmodium vivax Gametocytes Adherence to Bone Marrow Endothelial Cells
Frontiers in Cellular and Infection Microbiology, 2021 In a Plasmodium vivax infection, it was shown a proportionally increased on gametocyte distribution within the bone marrow aspirant, suggesting a role of this organ as a reservoir for this parasite stage.
Luis Carlos Salazar Alvarez +17 more
doaj +1 more source
Next-generation sequencing of the CHO cell transcriptome [PDF]
BMC Proceedings, 2011 Since 1957 Chinese hamster ovary (CHO) cells are used for in vitro cultivation as they require assimilable low sustenance [1]. Today, CHO cell lines represent the most commonly used mammalian expression system for the production of therapeutic proteins and are considered as the mammalian equivalent of E. coli in research and biotechnology [2].
Becker, Jennifer +13 more
openaire +6 more sources
CD300LG improves the cytotoxic activity of CIK
Central European Journal of Immunology, 2017 To investigate the effect of CD300LG-γ induction on the cytotoxic activity of CIK. Eukaryotic expression plasmid hCD300LG-γ/pEGFP-C3, which can express human CD300LG-γ, was constructed and transfected into CHO cells by lipofectamine.
Qiuyue Wang +6 more
doaj +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 Aim. In this study we aimed to develop the methodology to change the antigen specificity of chimeric antibodies by replacing the variable region genes in the previously designed universal plasmid constructions pLK DT-17 and pHG DT-17 encoding the DT-17 ...
T. G. Samartseva +5 more
doaj +1 more source
Frontiers in Chemistry, 2021 The α1,6-fucosyltransferase (encoded by FUT8 gene) is the key enzyme transferring fucose to the innermost GlcNAc residue on an N-glycan through an α-1,6 linkage in the mammalian cells.
Ganglong Yang +5 more
doaj +1 more source
A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation [PDF]
, 2016 Glycosylation greatly influences the safety and efficacy of many of the highest-selling recombinant therapeutic proteins (rTPs). In order to define optimal cell culture feeding strategies that control rTP glycosylation, it is necessary to know how ...
Jimenez del Val, I +2 more
core +1 more source
CHO microRNA engineering is growing up : recent successes and future challenges [PDF]
, 2013 microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Barron, Niall +11 more
core +1 more source
Correction of the neuropathogenic human apolipoprotein E4 (APOE4) gene to APOE3 in vitro using synthetic RNA/DNA oligonucleotides (chimeraplasts) [PDF]
, 2005 Apolipoprotein E (apoE) is a multifunctional circulating 34-kDa protein, whose gene encodes single-nucleotide polymorphisms linked to several neurodegenerative diseases.
Dickson, JG +3 more
core +1 more source