Results 31 to 40 of about 663,360 (333)
High Throughput miRNA Screening Identifies miR-574-3p Hyperproductive Effect in CHO Cells
Biomolecules, 2021 CHO is the cell line of choice for the manufacturing of many complex biotherapeutics. The constant upgrading of cell productivity is needed to meet the growing demand for these life-saving drugs.
Živa Švab +7 more
doaj +1 more source
The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects [PDF]
, 2015 Funded by: •GW Pharmaceuticals Acknowledgements: The authors wish to thank Mrs Lesley Stevenson for technical support and Dr John Raymond, Dr Keith Parker and Dr Ethan Russo for providing human 5-HT1A CHO cells.
Cascio, Maria Grazia +4 more
core +1 more source
Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]
, 2008 Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Baranowski, Eric +4 more
core +3 more sources
Cell surface glycoproteins of CHO cells
Experimental Cell Research, 1986 Experimental Cell Research 165 (1986) 92-106. doi:10.1016/0014-4827(86)90535-5 ; Received by publisher: 1985-10-29 ; Harvest Date: 2016-01-04 12:19:39 ; DOI:10.1016/0014-4827(86)90535-5 ; Page Range: 92 ...
Thomas J. Raub, R.Michael Roberts
openaire +2 more sources
PLoS ONE, 2012 Cell microparticles (MPs) released in the extracellular milieu can embark plasma membrane and intracellular components which are specific of their cellular origin, and transfer them to target cells.
Gaëlle Gonzalez +5 more
doaj +1 more source
The Era of Gene Therapy: The Advancement of Lentiviral Vectors and Their Pseudotyping
VirusesOver 35 years of history, the field of gene therapy has undergone much progress. The initial concept—the replacement of dysfunctional genes with correct ones—has advanced to the next stage and reached the level of precise genome editing.
Bat-Erdene Jargalsaikhan +2 more
doaj +1 more source
Modulation of the Plasma Kallikrein-Kinin System Proteins Performed by Heparan Sulfate Proteoglycans
Frontiers in Physiology, 2017 Human plasma kallikrein-kinin system proteins are related to inflammation through bradykinin. In the proximity of its target cells, high molecular weight kininogen (H-kininogen) is the substrate of plasma kallikrein, which releases bradykinin from H ...
Guacyara Motta, Ivarne L. S. Tersariol
doaj +1 more source
Biological Research, 2022 Background Chinese hamster ovary cell line has been used routinely as a bioproduction factory of numerous biopharmaceuticals. So far, various engineering strategies have been recruited to improve the production efficiency of this cell line such as ...
Fatemeh Safari, Bahman Akbari
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Understanding cellular internalization pathways of silicon nanowires [PDF]
, 2017 BACKGROUND: Understanding how cells interact with nanomaterials is important for rational design of nanomaterials for nanomedicine and transforming them for clinical applications.
Huang, Yimin, McNear, Kelly, Yang, Chen
core +1 more source