Results 131 to 140 of about 89,075 (280)

Improvement of survival outcomes of cholangiocarcinoma by ultrasonography surveillance: Multicenter retrospective cohorts

Heliyon
Background: Most cholangiocarcinoma (CCA) patients present with late stage of disease because of the difficulty to diagnosis at an early stage, resulting in poor survival of CCA patients.
Nittaya Chamadol, Vallop Laopaiboon, Apiwat Jareanrat, Vasin Thanasukarn, Tharatip Srisuk, Vor Luvira, Poowanai Sarkhampee, Winai Ungpinitpong, Phummarat Khamvijite, Yutthapong Chumnanua, Nipath Nethuwakul, Passakorn Sodarat, Samrit Thammarit, Anchalee Techasen, Jaruwan Thuanman, Chaiwat Tawarungruang, Bandit Thinkhamrop, Prakasit Sa-Ngiamwibool, Watcharin Loilome, Piya Prajumwongs, Attapol Titapun   +20 more
doaj   +1 more source

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.

Cancer Cell, 2021
Silvia Affò, A. Nair, F. Brundu, Aashreya Ravichandra, S. Bhattacharjee, M. Matsuda, Likang Chin, A. Filliol, W. Wen, Xinhua Song, Aubrianna Decker, Jeremy Worley, J. Caviglia, Lexing Yu, Deqi Yin, Yoshinobu Saito, Thomas M. Savage, R. Wells, M. Mack, L. Zender, Nicholas Arpaia, H. Remotti, R. Rabadán, P. Sims, Anne-Laure Leblond, A. Weber, M. Riener, B. Stockwell, Jellert T. Gaublomme, J. Llovet, R. Kalluri, G. Michalopoulos, E. Seki, D. Sia, Xin Chen, A. Califano, R. Schwabe   +36 more
semanticscholar   +1 more source

Disease Burden of Liver Cancer and Its Underlying Etiologies Globally and in China From 1990 to 2021: Results From the Global Burden of Disease Study 2021

Portal Hypertension &Cirrhosis, EarlyView.
Liver cancer remains a leading global health threat, imposing a substantial and growing burden of disease and disability. This study explores the epidemiologic landscape of liver cancer worldwide and within China over recent decade using Global Burden of Disease database 2021 study.
Jiaqi Ruan, Hangkai Huang, Chengfu Xu
wiley   +1 more source

Metabolic Reprogramming in Cholangiocarcinoma.

Journal of Hepatology, 2022
C. Raggi, M. Taddei, C. Rae, C. Braconi, F. Marra   +4 more
semanticscholar   +1 more source

NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic

Small, EarlyView.
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho, Katharina Schmidt, Christopher Lambert, Lili Jia, Vignesh Venkatakrishnan, Luisa Mehr, Johan Bylund, Klemens Rottner, Marc Stadler, Theresia E. B. Stradal, Philipp Klahn   +10 more
wiley   +1 more source

Alterations of the oral microbiome in patients reinfected with SARS‐CoV‐2 omicron variants

VIEW, EarlyView.
We studied the oral microbiome (the community of microbes in the mouth) in people who were reinfected with the omicron variant of SARS‐CoV‐2 and compared it with healthy individuals and other respiratory illness groups. By sequencing tongue‐coating samples from large cohorts, we identified microbial shifts linked to Omicron reinfection and built a ...
Benchen Rao, Yongjian Zhou, Tong Ren, Hongxia Liang, Lei Li, Yakun Xu, Haiyu Wang, Xiaoping Wang, Xiaoli Ni, Xiaoning Wang, Hanmeng Liu, Xiaoli Jin, Qiaoxia Chen, Xuemei Wang, Yawen Zou, Ying Sun, Zhigang Ren, Zujiang Yu   +17 more
wiley   +1 more source

Establishment and Characterization of MCA23, a Novel Mouse Intrahepatic Cholangiocarcinoma Cell Line. [PDF]

Cancer Med
ABSTRACT Introduction Intrahepatic cholangiocarcinoma (ICC) is an aggressive type of malignancy. Recent advancements have highlighted the importance of the tumor immune microenvironment in therapeutic responses and prognosis. However, the lack of a mouse‐derived ICC cell line and current mouse models limit explorations of the TME in ICC.
He Y, Luo Y, Chen L, Wang Y, Liu B, Sun M, Gong W, Tian X, Guo L, Zhang Q, Wu Q, Chen L, Guo H.   +12 more
europepmc   +2 more sources

Cholangiocarcinoma — evolving concepts and therapeutic strategies

Nature Reviews Clinical Oncology, 2017
Sumera Rizvi, Shahid A. Khan, C. Hallemeier, R. Kelley, G. Gores   +4 more
semanticscholar   +1 more source

Mass spectrometry‐based mitochondrial proteomics for cancer biomarker discovery

VIEW, EarlyView.
Figure.1 Schematic diagram of MS‐based mitochondrial proteomics for cancer biomarker discovery. The workflow highlights the integration of advanced technological platforms in mitochondrial proteomics and their application in cancer biomarker discovery.
Zheng Cao, ZiKun Song, Weijie Zhou, Xiaohui Liu, Yanling Liu, Peng R. Chen, Kun Qian   +6 more
wiley   +1 more source

Clinical Need and Research Investment for Liver Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Liver cancer incidence and mortality rates have been rising in comparison to other common cancers, but research funding has not been commensurate. ABSTRACT Aim This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC ...
Romario Nguyen, Fatema Safri, Ankur Sharma, Jessica Howell, Stuart K. Roberts, Simone I. Strasser, Amany Zekry, Alan Wigg, Leon A. Adams, Michael Wallace, Golo Ahlenstiel, Eleonora Feletto, Karen Canfell, Tracey O'Brien, Jacob George, Liang Qiao   +15 more
wiley   +1 more source