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Macrophages in cholangiopathies
Current Opinion in Gastroenterology, 2021Purpose of review Cholangiopathies are a heterogeneous class of liver diseases where cholangiocytes are the main targets of liver injury. Although available and emerging therapies mainly target bile acids (ursodeoxycholic acid/UDCA, 24-Norursodeoxycholic acid/norUDCA) and related signaling pathways (obeticholic acid, fibrates ...
Alix, Bruneau +2 more
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Journal of Hepatology, 2006
Bile ducts are supplied with blood exclusively via hepatic arteries. Obstruction of large arteries is rapidly compensated for by the opening of preexisting intrahepatic or transcapsular collateral arteries, which prevents ischemic damage. Ischemic bile duct injury may occur when small hepatic arteries or the peribiliary vascular plexus are injured, or ...
Pierre, Deltenre +1 more
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Bile ducts are supplied with blood exclusively via hepatic arteries. Obstruction of large arteries is rapidly compensated for by the opening of preexisting intrahepatic or transcapsular collateral arteries, which prevents ischemic damage. Ischemic bile duct injury may occur when small hepatic arteries or the peribiliary vascular plexus are injured, or ...
Pierre, Deltenre +1 more
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Ischemic cholangiopathy: An update
Clinics and Research in Hepatology and Gastroenterology, 2020Aurélie Plessier +2 more
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Current Treatment Options in Gastroenterology, 2004
AIDS is an advanced disease with systemic and infectious complications that can be fatal. When a patient with AIDS presents with right upper quadrant or midepigastric pain, cholestasis, and symptoms of cholangitis, AIDS cholangiopathy should be suspected and appropriate diagnostic and therapeutic interventions should be initiated.
Tony E., Yusuf, Todd H., Baron
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AIDS is an advanced disease with systemic and infectious complications that can be fatal. When a patient with AIDS presents with right upper quadrant or midepigastric pain, cholestasis, and symptoms of cholangitis, AIDS cholangiopathy should be suspected and appropriate diagnostic and therapeutic interventions should be initiated.
Tony E., Yusuf, Todd H., Baron
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Pathophysiology of Cholangiopathies
Journal of Clinical Gastroenterology, 2005The diseases of the intrahepatic biliary tree are a large group of potentially evolutive congenital and acquired liver disorders affecting both the adult and pediatric populations. They represent a relevant cause of liver-related morbidity and mortality and an important indication for liver transplantation, particularly in children. While the practical
STRAZZABOSCO M, FABRIS, LUCA, SPIRLI C.
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The Intrahepatic Cholangiopathies
Seminars in Liver Disease, 1998The intrahepatic biliary epithelial cells or cholangiocytes are the primary focus of injury in many congenital and acquired liver diseases of childhood. Although cholangiocytes account for only 3 to 5% of the liver cell population, injury and progressive loss of intrahepatic bile ducts can result in considerable morbidity and mortality.
A, Birnbaum, F J, Suchy
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