Results 151 to 160 of about 102,302 (358)

IgG4-Seronegative Autoimmune Pancreatitis and Sclerosing Cholangitis [PDF]

, 2015
Allon Kahn, Anitha Yadav, M. Edwyn Harrison   +2 more
openalex   +1 more source

Incidence and Mortality Risks of Gastrointestinal Cancers During Working‐Age Period: Trends and Disparities in 204 Countries and Territories (1990–2021)

Med Research, EarlyView.
This comprehensive analysis of gastrointestinal (GI) cancer risk reveals that globally, one in 46 people will develop and one in 73 will die from GI cancers during working age (15–64 years), with 2021 incidence and mortality risks of 2.19% and 1.37%, respectively. Key findings demonstrate striking gender disparities, with males facing nearly double the
Yiming Song, Zhongge Ji, Xunbing Zhang, Qian Liang, Zeyu Li, Xiaojie Huang, Jinnan Chen, Yujie Zhou, Xinyuan Wang, Zhao Li, Liuyi Yang, Yixin Qian, Xiaolu Lin, Qingwei Zhang, Xiaobo Li   +14 more
wiley   +1 more source

Therapeutic potential of tetrahydroxylated bile acids in reducing liver injury: Insights from the Zfyve19−/− mouse model

Pediatric Investigation, EarlyView.
THBA (3α,6α,7α,12α‐Tetrahydroxy‐10β,13β‐pentanoic acid) administration can alleviate cholestatic liver injury, hepatocellular necrosis, inflammatory response, bile duct hyperplasia, and portal fibrosis in the Zfyve19−/− mouse model. This evaluation encompasses various parameters, including serum biochemistry, liver histology, immunostaining, and ...
Li Wang, Yue Yu, Jiayan Feng, Yanan Zhang, Renxue Wang, Huiyu She, Teng Liu, Victor Ling, Jianshe Wang   +8 more
wiley   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source

Infections after liver transplantation: An analysis of 101 consecutive cases [PDF]

, 1988
Esquivel, C, Ho, M, Iwatsuki, S, Kusne, S, Makowka, L, Singh, N, Starzl, TE, Stephen Dummer, J, Tzakis, AG   +8 more
core   +1 more source

Editorial: serologic antibodies in primary sclerosing cholangitis—a tell‐tale sign of compromised gut‐liver immunity? Authors' reply [PDF]

, 2020
Ewa Wunsch, Piotr Milkiewicz
openalex   +1 more source

Machine Learning‐Based Risk‐Adjusted CUSUM Control Chart for Monitoring Readmission Rate Following PTBD Catheter Placement

Quality and Reliability Engineering International, EarlyView.
ABSTRACT Percutaneous transhepatic biliary drainage (PTBD) catheter placement is known to have a high readmission rate. This work focuses on monitoring the change in readmission rate after a new clinical paradigm for post‐procedural care is implemented for the PTBD procedures.
Muhammed Aljifri, Yanjun Qian, Kunal Patel   +2 more
wiley   +1 more source

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

164 A Historical Cohort Study Comparing the Clinical Outcome of Ulcerative Colitis and Crohn's Disease in the Presence of Primary Sclerosing Cholangitis

, 2012
Udayakumar Navaneethan, Preethi G.K. Venkatesh, Bret A. Lashner, Feza H. Remzi, Pokala R. Kiran, Bo Shen, John J. Fung   +6 more
openalex   +1 more source

Machine Learning‐Based Prediction of Life‐Threatening Complications During Hemodialysis in Hospitalized Patients With Poor General Conditions

Artificial Organs, EarlyView.
A machine learning model using predialysis data predicted sudden events during or after hemodialysis with high accuracy (auROC: 0.889). The key predictors included emergency hospitalization, recent surgery, high heart rate, low albumin levels, and high CRP.
Naotaka Kato, Takeshi Goto, Tomoyuki Ohira, Hirotaka Kinoshita, Kugo Kurokawa, Kouhei Naganuma, Chikako Ohminato, Junko Ogasawara, Shingo Hatakeyama, Yoshihiro Sasaki, Kazuyoshi Hirota, Chikara Ohyama   +11 more
wiley   +1 more source