Results 11 to 20 of about 54,665 (221)

Intestinal microbiome dysbiosis in alcohol-dependent patients and its effect on rat behaviors

mBio, 2023
Alcohol dependence (AD) is a worldwide epidemic of psychiatric disorders. Gut microbiota dysbiosis may be involved in the development of AD. Recently, the number of studies on the relationship between gut microbiota and alcohol is increasing.
Chuansheng Wang, Junli Yan, Keda Du, Shuai Liu, Jiali Wang, Qi Wang, Huajie Zhao, Min Li, Dong Yan, Ruiling Zhang, Fan Yang   +10 more
doaj   +1 more source

Crosstalk between Opioid and Anti-Opioid Systems: An Overview and Its Possible Therapeutic Significance

Biomolecules, 2020
Opioid peptides and receptors are broadly expressed throughout peripheral and central nervous systems and have been the subject of intense long-term investigations.
Ewa Gibula-Tarlowska, Jolanta H. Kotlinska   +1 more
doaj   +1 more source

Effects of Various LED Light Spectra on Growth, Gonadal Development, and Growth-/Reproduction-Related Hormones in the Juvenile Red Spotted Grouper, Epinephelus akaara

Animals, 2023
The light spectrum is a key environmental cue involved in growth and reproduction in teleosts. This study investigated the effects of exposure on juvenile red spotted grouper exposed to white (control), red (590 nm), blue (480 nm), and green (520 nm ...
Wengang Xu, Huafeng Zou, Jun Zeng, Weiping Mei, SongHee Choi   +4 more
doaj   +1 more source

The Role of Bile in the Regulation of Exocrine Pancreatic Secretion [PDF]

, 1992
As early as 1926 Mellanby (1) was able to show that introduction of bile into the duodenum of anesthetized cats produces a copious flow of pancreatic juice.
Adamczyk W, Andrén-Sandberg A, Aronchick CA, Björnsson OG, Björnsson OG, Brand SJ, Burhol PG, Davies HA, Dragstedt LR, Erlinger S, Eyre-Brook IA, Fausa O, Fiedler F, Forell MM, Forell MM, Forell MM, Forell MM, Forell MM, Frühauf S, Fölsch UR, Geratz JD, Gomez G, Green GM, Gries E, Grundy SM, Hanssen LE, Hartmann W, Hellmann G, Holtermuller KH, Holtermuller KH, Hotz J, Ivy AC, Kataoka K, Konturek SJ, Koop I, Koop I, Koop I, Koop I, Koop I, Kurosawa H, Kuroyanagi Y, Lagerlöf HO, Lehnert P, Lueth HC, Malagelada J-R, Malagelada J-R, Malagelada J-R, Mellanby J, Meyer JH, Miyasaka K, Miyasaka K, Miyasaka K, Miyasaka K, Nakamura R, Nakamura R, Namba M, Nustede R, Ohta H, Osnes M, Osnes M, Osnes M, Osnes M, Otte M, Peter Lehnert, Riepl RL, Riepl RL, Riepl RL, Riepl RL, Rudolf L. Riepl, Schaffalitzky de Muckadell OB, Shiratori K, Smallwood RA, Staub VL, Thomas JE, van Levan H, Wormsley KG   +75 more
core   +1 more source

Intra-islet GLP-1, but not CCK, is necessary for β-cell function in mouse and human islets [PDF]

, 2020
Glucagon-like peptide 1 (GLP-1) and cholecystokinin (CCK) are gut-derived peptide hormones known to play important roles in the regulation of gastrointestinal motility and secretion, appetite, and food intake.
Davis, Dawn, de Souza, Arnaldo Henrique, Kibbe, Carly R., Linnemann, Amelia K., Merrins, Matthew J., Saghafi, Samuel T., Tang, Jiayin, Yadev, Amanjot Kaur   +7 more
core   +1 more source

Stearic acid induces CCK and GLP-1 upregulation via GPR120/PLC-β, leading to reduced appetite in Hu sheep fed with rice straw

Frontiers in Veterinary Science, 2022
Due to the poor palatability of straw, feeding untreated rice straw reduces ruminant feed intake, thus affecting the production efficiency of animal husbandry.
Xi Chen, Xintian Nie, Huanhuan Wang, Shuping Yan, Yuanshu Zhang   +4 more
doaj   +1 more source

A descending inhibitory mechanism of nociception mediated by an evolutionarily conserved neuropeptide system in Drosophila

eLife, 2023
Nociception is a neural process that animals have developed to avoid potentially tissue-damaging stimuli. While nociception is triggered in the peripheral nervous system, its modulation by the central nervous system is a critical process in mammals ...
Izumi Oikawa, Shu Kondo, Kao Hashimoto, Akiho Yoshida, Megumi Hamajima, Hiromu Tanimoto, Katsuo Furukubo-Tokunaga, Ken Honjo   +7 more
doaj   +1 more source

The Role of Pepsinogenes and Some Intestinal Hormones in Pathogenesis of Gastroesophageal Reflux Disease [PDF]

, 2018
80 patients with gastroesophageal reflux disease (GERD) were examined. The diagnosis of GERD was based on the history of the disease, complaints of patients, the results of daily monitoring of pH in the lower third of the esophagus, data of ...
Boichuk, V. (Vira)
core   +2 more sources

The Role of GI Peptides in Functional Dyspepsia and Gastroparesis: A Systematic Review

Frontiers in Psychiatry, 2020
Functional dyspepsia (FD) and gastroparesis (GP) are common disorders of the upper gastrointestinal tract. The pathophysiology of these conditions is likely to be heterogenous, and factors such as altered motility, sensitivity and response to nutrition ...
Karen Van den Houte, Emidio Scarpellini, Wout Verbeure, Hideki Mori, Jolien Schol, Imke Masuy, Florencia Carbone, Jan Tack   +7 more
doaj   +1 more source

Mechanism of Action and Structure–Activity Relationships of Tetracyclic Small Molecules Acting as Universal Positive Allosteric Modulators of the Cholecystokinin Receptor

Membranes, 2023
As part of an ongoing effort to develop a drug targeting the type 1 cholecystokinin receptor (CCK1R) to help prevent and/or treat obesity, we recently performed a high throughput screening effort of small molecules seeking candidates that enhanced the ...
Daniela G. Dengler, Kaleeckal G. Harikumar, Alice Yen, Eduard A. Sergienko, Laurence J. Miller   +4 more
doaj   +1 more source