Results 21 to 30 of about 36,127 (235)

Impact of central antagonist of cholecystokinin-1 receptors GB-115 on cognitive functions in patients with Generalized Anxiety Disorder

open access: yesEuropean Psychiatry, 2022
Introduction Generalized anxiety disorder (GAD) is associated with reduced attention, inhibition, decrease of processing speed. The impact of a new peptide antagonist of central cholecystokinin-1 receptors (GB-115) on cognitive processes in patients ...
O. Dorofeeva   +3 more
doaj   +1 more source

Structure-activity relationship data and ligand-receptor interactions identify novel agonists consistent with sulfakinin tissue-specific signaling in Drosophila melanogaster heart

open access: yesFrontiers in Bioscience-Landmark, 2022
Background: The structures and activities of invertebrate sulfakinins that influence gut motility and heart rate are like the vertebrate cholecystokinin (CCK) peptides.
Ruthann Nichols   +2 more
doaj   +1 more source

Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk

open access: yesJournal of Lipid Research, 2002
The relationship between obesity and cholesterol cholelithiasis is not well understood at physiologic or genetic levels. To clarify whether obesity per se leads to increased prevalence of cholelithiasis, we examined cholesterol gallstone susceptibility ...
Guylaine Bouchard   +4 more
doaj   +1 more source

Cholecystokinin and the hormone concept

open access: yesEndocrine Connections, 2021
The birth certificate for endocrinology was Bayliss’ and Starlin g’s demonstration in 1902 that regulation of bodily functions is not only neuronal but al so due to blood-borne messengers. Starling named these messengers hormones.
Jens F Rehfeld
doaj   +1 more source

Cholecystokinin receptor antagonists [PDF]

open access: yes, 1984
Since 1979 three classes of cholecystokinin receptor antagonists have been described: 1) derivatives of cyclic nucleotides, 2) derivatives of amino acids, and 3) C-terminal fragments or partial sequences of cholecystokinin.
R. T. Jensen, J. D. Gardner
core   +1 more source

Immune recognition of affinity‐labelled cholecystokinin receptor [PDF]

open access: yes, 2005
International audienceThe present study was undertaken to characterize the immune recognition of pancreatic cholecystokinin receptor by an anti‐cholecystokinin antibody. Cholecystokinin receptor from pancreatic plasma membranes was photoaffinity labelled
Jimenez, Juan   +5 more
core   +1 more source

Utilizing Peptide Ligand GPCRs to Image and Treat Pancreatic Cancer

open access: yesBiomedicines, 2018
It is estimated that early detection of pancreatic ductal adenocarcinoma (PDAC) could increase long-term patient survival by as much as 30% to 40% (Seufferlein, T. et al., Nat. Rev. Gastroenterol. Hepatol. 2016, 13, 74–75).
Gail L. Matters, John F. Harms
doaj   +1 more source

Cyclic nucleotide antagonists of cholecystokinin: structural requirements for interaction with the cholecystokinin receptor [PDF]

open access: yes, 1982
Previously, we have found that, in pancreatic acini, butyryl derivatives of cGMP antagonize the action of cholecystokinin by inhibiting binding of the peptide to its membrane receptors.
R. T. Jensen   +3 more
core   +1 more source

Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition

open access: yesCell Reports, 2017
Although Netos are considered auxiliary subunits critical for kainate receptor (KAR) function, direct evidence for their regulation of native KARs is limited.
Megan S. Wyeth   +13 more
doaj   +1 more source

Interactions of Cholecystokinin and Glutamatergic Systems in Feeding Behavior of Neonatal Chickens [PDF]

open access: yesArchives of Razi Institute, 2022
This study aimed to assess the possible feeding behavior alterations by central interactions of cholecystokinin (CCK) and glutamatergic systems in neonatal chickens.
M Jelokhani   +3 more
doaj   +1 more source

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