Results 21 to 30 of about 55,036 (230)

Biochemistry of the Endocrine Heart

Biology, 2022
Production and release of natriuretic peptides and other vasoactive peptides are tightly regulated in mammalian physiology and involved in cardiovascular homeostasis.
Jens P. Goetze, Emil D. Bartels, Theodor W. Shalmi, Lilian Andraud-Dang, Jens F. Rehfeld   +4 more
doaj   +1 more source

Effect of Intraduodenal Bile and Na-Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Secretin, Pancreatic Polypeptide, and Gastrin in Man [PDF]

, 1990
The effect of intraduodenally administered cattle bile (CB) and Na-taurodeoxycholate (TDC) on basal pancreatic secretion and plasma levels of secretin, pancreatic polypeptide (PP), and gastrin were investigated on two separate days in 10 fasting ...
A. Scharl, Aronchick C A, Bjornsson O G, Bondesen S, Burhol P G, Burhol P G, Burhol P G, Carey M C, Davies H A, Dragstedt L R, F. Fiedler, Fahrenkrug J, Flaten O, Florholmen J, Forell M M, Forell M M, Greenberg G R, Gries E, Grossman M I, Hanssen L E, Hartmann W, Hunter W M, I. Hempen, J. Teufel, Jorde R, Konturek S J, Lehnert P, Londong W, Lonovics J, Malagelada J-R., Malagelada J-R., Miyasaka K, Miyazaki K, Moreland H J, Morris B J, Osnes M, Osnes M, Otte M, P. G. Burhol, P. Lehnert, Petersen H, R. L. Riepl, Scatchard G, Schaffalitzky de Muckadell O B, Schwartz T W, Thomas J E, Wormsley K G   +46 more
core   +1 more source

Impact of central antagonist of cholecystokinin-1 receptors GB-115 on cognitive functions in patients with Generalized Anxiety Disorder

European Psychiatry, 2022
Introduction Generalized anxiety disorder (GAD) is associated with reduced attention, inhibition, decrease of processing speed. The impact of a new peptide antagonist of central cholecystokinin-1 receptors (GB-115) on cognitive processes in patients ...
O. Dorofeeva, M. Metlina, A. Chepeliuk, M. Vinogradova   +3 more
doaj   +1 more source

Lipase inhibition attenuates the acute inhibitory effects of oral fat on food intake in healthy subjects [PDF]

, 2003
The lipase inhibitor, orlistat, is used in the treatment of obesity and reduces fat absorption by about 30%. However, the mean weight loss induced by orlistat is less than expected for the degree of fat malabsorption.
Feinle-Bisset, C., Horowitz, M., O'Donovan, D., Wishart, J.   +3 more
core   +2 more sources

Structure-activity relationship data and ligand-receptor interactions identify novel agonists consistent with sulfakinin tissue-specific signaling in Drosophila melanogaster heart

Frontiers in Bioscience-Landmark, 2022
Background: The structures and activities of invertebrate sulfakinins that influence gut motility and heart rate are like the vertebrate cholecystokinin (CCK) peptides.
Ruthann Nichols, Chloe Bass, Chris Katanski   +2 more
doaj   +1 more source

Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk

Journal of Lipid Research, 2002
The relationship between obesity and cholesterol cholelithiasis is not well understood at physiologic or genetic levels. To clarify whether obesity per se leads to increased prevalence of cholelithiasis, we examined cholesterol gallstone susceptibility ...
Guylaine Bouchard, Derek Johnson, Tonya Carver, Beverly Paigen, Martin C. Carey   +4 more
doaj   +1 more source

Cholecystokinin and the hormone concept

Endocrine Connections, 2021
The birth certificate for endocrinology was Bayliss’ and Starlin g’s demonstration in 1902 that regulation of bodily functions is not only neuronal but al so due to blood-borne messengers. Starling named these messengers hormones.
Jens F Rehfeld
doaj   +1 more source

Pancreatic exocrine insufficiency after bariatric surgery [PDF]

, 2017
Morbid obesity is a lifelong disease, and all patients require complementary follow-up including nutritional surveillance by a multidisciplinary team after bariatric procedures.
Arnelo, Urban, Haas, Stephan L., Löhr, J. -Matthias, Martin, Lena, Rutkowski, Wiktor, Thorell, Anders, Valente, Roberto, Vujasinovic, Miroslav   +7 more
core   +1 more source

Utilizing Peptide Ligand GPCRs to Image and Treat Pancreatic Cancer

Biomedicines, 2018
It is estimated that early detection of pancreatic ductal adenocarcinoma (PDAC) could increase long-term patient survival by as much as 30% to 40% (Seufferlein, T. et al., Nat. Rev. Gastroenterol. Hepatol. 2016, 13, 74–75).
Gail L. Matters, John F. Harms
doaj   +1 more source

Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition

Cell Reports, 2017
Although Netos are considered auxiliary subunits critical for kainate receptor (KAR) function, direct evidence for their regulation of native KARs is limited.
Megan S. Wyeth, Kenneth A. Pelkey, Xiaoqing Yuan, Geoffrey Vargish, April D. Johnston, Steven Hunt, Calvin Fang, Daniel Abebe, Vivek Mahadevan, André Fisahn, Michael W. Salter, Roderick R. McInnes, Ramesh Chittajallu, Chris J. McBain   +13 more
doaj   +1 more source