Results 11 to 20 of about 36,127 (235)

Genetic variability in the cholecystokinin A receptor affects lipid profile and glucose tolerance in patients with polycystic ovary syndrome [PDF]

open access: yes, 2022
Introduction Cholecystokinin (CCK) is involved in several metabolic pathways, and CCK agonists are considered as a potential novel treatment option in populations with increased metabolic risk, including polycystic ovary syndrome (PCOS).
Andrej Janež   +6 more
core   +1 more source

Effects of Various LED Light Spectra on Growth, Gonadal Development, and Growth-/Reproduction-Related Hormones in the Juvenile Red Spotted Grouper, Epinephelus akaara

open access: yesAnimals, 2023
The light spectrum is a key environmental cue involved in growth and reproduction in teleosts. This study investigated the effects of exposure on juvenile red spotted grouper exposed to white (control), red (590 nm), blue (480 nm), and green (520 nm ...
Wengang Xu   +4 more
doaj   +1 more source

Stearic acid induces CCK and GLP-1 upregulation via GPR120/PLC-β, leading to reduced appetite in Hu sheep fed with rice straw

open access: yesFrontiers in Veterinary Science, 2022
Due to the poor palatability of straw, feeding untreated rice straw reduces ruminant feed intake, thus affecting the production efficiency of animal husbandry.
Xi Chen   +4 more
doaj   +1 more source

A descending inhibitory mechanism of nociception mediated by an evolutionarily conserved neuropeptide system in Drosophila

open access: yeseLife, 2023
Nociception is a neural process that animals have developed to avoid potentially tissue-damaging stimuli. While nociception is triggered in the peripheral nervous system, its modulation by the central nervous system is a critical process in mammals ...
Izumi Oikawa   +7 more
doaj   +1 more source

Regulation of fat-stimulated neurotensin secretion in healthy subjects [PDF]

open access: yes, 2008
CONTEXT: Cholecystokinin (CCK) and neurotensin are stimulated during meal intake by the presence of fat in the small intestine. The sequence of events suggests that fat hydrolysis is crucial for triggering the release.
Drewe, J.   +3 more
core   +1 more source

The Role of GI Peptides in Functional Dyspepsia and Gastroparesis: A Systematic Review

open access: yesFrontiers in Psychiatry, 2020
Functional dyspepsia (FD) and gastroparesis (GP) are common disorders of the upper gastrointestinal tract. The pathophysiology of these conditions is likely to be heterogenous, and factors such as altered motility, sensitivity and response to nutrition ...
Karen Van den Houte   +7 more
doaj   +1 more source

Mechanism of Action and Structure–Activity Relationships of Tetracyclic Small Molecules Acting as Universal Positive Allosteric Modulators of the Cholecystokinin Receptor

open access: yesMembranes, 2023
As part of an ongoing effort to develop a drug targeting the type 1 cholecystokinin receptor (CCK1R) to help prevent and/or treat obesity, we recently performed a high throughput screening effort of small molecules seeking candidates that enhanced the ...
Daniela G. Dengler   +4 more
doaj   +1 more source

Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion [PDF]

open access: yes, 2010
Context: Glucagon-like peptide-1 (GLP-1) is produced by specialized cells in the gut and secreted in response to carbohydrates and lipids. The mechanisms regulating fat-stimulated GLP-1 release have, however, not been clarified in detail.
Schirra, Joerg   +5 more
core   +1 more source

Biochemistry of the Endocrine Heart

open access: yesBiology, 2022
Production and release of natriuretic peptides and other vasoactive peptides are tightly regulated in mammalian physiology and involved in cardiovascular homeostasis.
Jens P. Goetze   +4 more
doaj   +1 more source

Conduction of activity between muscles in the terminal region of the common bile duct and in the neighboring duodenum [PDF]

open access: yes, 1976
The relationship between muscle activity at the terminal region of the common bile duct and the duodenal muscle was examined in rabbits. The rhythmic muscle activity in the terminal region was synchronous with duodenal muscle activity.
Nakayama, Sosogu, Fukuda, Hiroyuki
core   +1 more source

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