Results 11 to 20 of about 28,880 (163)

Effects of Various LED Light Spectra on Growth, Gonadal Development, and Growth-/Reproduction-Related Hormones in the Juvenile Red Spotted Grouper, Epinephelus akaara

Animals, 2023
The light spectrum is a key environmental cue involved in growth and reproduction in teleosts. This study investigated the effects of exposure on juvenile red spotted grouper exposed to white (control), red (590 nm), blue (480 nm), and green (520 nm ...
Wengang Xu, Huafeng Zou, Jun Zeng, Weiping Mei, SongHee Choi   +4 more
doaj   +1 more source

Stearic acid induces CCK and GLP-1 upregulation via GPR120/PLC-β, leading to reduced appetite in Hu sheep fed with rice straw

Frontiers in Veterinary Science, 2022
Due to the poor palatability of straw, feeding untreated rice straw reduces ruminant feed intake, thus affecting the production efficiency of animal husbandry.
Xi Chen, Xintian Nie, Huanhuan Wang, Shuping Yan, Yuanshu Zhang   +4 more
doaj   +1 more source

A descending inhibitory mechanism of nociception mediated by an evolutionarily conserved neuropeptide system in Drosophila

eLife, 2023
Nociception is a neural process that animals have developed to avoid potentially tissue-damaging stimuli. While nociception is triggered in the peripheral nervous system, its modulation by the central nervous system is a critical process in mammals ...
Izumi Oikawa, Shu Kondo, Kao Hashimoto, Akiho Yoshida, Megumi Hamajima, Hiromu Tanimoto, Katsuo Furukubo-Tokunaga, Ken Honjo   +7 more
doaj   +1 more source

The Role of GI Peptides in Functional Dyspepsia and Gastroparesis: A Systematic Review

Frontiers in Psychiatry, 2020
Functional dyspepsia (FD) and gastroparesis (GP) are common disorders of the upper gastrointestinal tract. The pathophysiology of these conditions is likely to be heterogenous, and factors such as altered motility, sensitivity and response to nutrition ...
Karen Van den Houte, Emidio Scarpellini, Wout Verbeure, Hideki Mori, Jolien Schol, Imke Masuy, Florencia Carbone, Jan Tack   +7 more
doaj   +1 more source

Mechanism of Action and Structure–Activity Relationships of Tetracyclic Small Molecules Acting as Universal Positive Allosteric Modulators of the Cholecystokinin Receptor

Membranes, 2023
As part of an ongoing effort to develop a drug targeting the type 1 cholecystokinin receptor (CCK1R) to help prevent and/or treat obesity, we recently performed a high throughput screening effort of small molecules seeking candidates that enhanced the ...
Daniela G. Dengler, Kaleeckal G. Harikumar, Alice Yen, Eduard A. Sergienko, Laurence J. Miller   +4 more
doaj   +1 more source

Biochemistry of the Endocrine Heart

Biology, 2022
Production and release of natriuretic peptides and other vasoactive peptides are tightly regulated in mammalian physiology and involved in cardiovascular homeostasis.
Jens P. Goetze, Emil D. Bartels, Theodor W. Shalmi, Lilian Andraud-Dang, Jens F. Rehfeld   +4 more
doaj   +1 more source

Impact of central antagonist of cholecystokinin-1 receptors GB-115 on cognitive functions in patients with Generalized Anxiety Disorder

European Psychiatry, 2022
Introduction Generalized anxiety disorder (GAD) is associated with reduced attention, inhibition, decrease of processing speed. The impact of a new peptide antagonist of central cholecystokinin-1 receptors (GB-115) on cognitive processes in patients ...
O. Dorofeeva, M. Metlina, A. Chepeliuk, M. Vinogradova   +3 more
doaj   +1 more source

Structure-activity relationship data and ligand-receptor interactions identify novel agonists consistent with sulfakinin tissue-specific signaling in Drosophila melanogaster heart

Frontiers in Bioscience-Landmark, 2022
Background: The structures and activities of invertebrate sulfakinins that influence gut motility and heart rate are like the vertebrate cholecystokinin (CCK) peptides.
Ruthann Nichols, Chloe Bass, Chris Katanski   +2 more
doaj   +1 more source

Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk

Journal of Lipid Research, 2002
The relationship between obesity and cholesterol cholelithiasis is not well understood at physiologic or genetic levels. To clarify whether obesity per se leads to increased prevalence of cholelithiasis, we examined cholesterol gallstone susceptibility ...
Guylaine Bouchard, Derek Johnson, Tonya Carver, Beverly Paigen, Martin C. Carey   +4 more
doaj   +1 more source

Cholecystokinin and the hormone concept

Endocrine Connections, 2021
The birth certificate for endocrinology was Bayliss’ and Starlin g’s demonstration in 1902 that regulation of bodily functions is not only neuronal but al so due to blood-borne messengers. Starling named these messengers hormones.
Jens F Rehfeld
doaj   +1 more source