Results 11 to 20 of about 39,125 (240)

Identification and Discrimination of Sulfated and Unsulfated Gut-Hormone Biomarkers in Human Serum by Nanopore. [PDF]

Small
This study discriminates between sulfated and unsulfated cholecystokinin‐8 gut‐hormone forms at single‐molecule‐level resolution. Using an aerolysin nanopore embedded in a hybrid lipid‐polymer membrane, the system produces distinct electrical signatures enabling highly sensitive detection, even in 20% human serum.
Iesu L, Bacri L, Pelta J, Cressiot B.
europepmc   +2 more sources

Sacubitril/valsartan increases postprandial gastrin and cholecystokinin in plasma [PDF]

Endocrine Connections, 2020
Aims: Neprilysin degrades natriuretic peptides in circulation and is also suggested to degrade the gut hormones gastrin and cholecystokinin. Neprilysin inhibition has become a therapeutic strategy and thus a regimen in need of further testing in terms of
Ulrik Ø Andersen, Dijana Terzic, Nicolai Jacob Wewer Albrechtsen, Peter Dall Mark, Peter Plomgaard, Jens F Rehfeld, Finn Gustafsson, Jens P Goetze   +7 more
doaj   +2 more sources

Disordered pancreatic and gastrointestinal hormone responses to nutrient stimulation in Zambian children with severe acute malnutrition. [PDF]

Exp Physiol
Abstract Nutrient sensing enables the body to detect and respond to nutrient availability through hormonal regulation. In this study, we examined nutrient‐stimulated hormonal responses in children with severe acute malnutrition (SAM) compared with hospitalized (HC) and community (CC) child comparators.
Besa E, Phiri R, Tembo A, Nayame G, Ngongola A, Rehfeld J, Hartmann B, Frost G, Heimburger DC, Kelly P.   +9 more
europepmc   +2 more sources

Placebo and nocebo effects on pain through the lens of the predictive brain: Neurobiological mechanisms and translational implications. [PDF]

Exp Physiol
Abstract Placebo and nocebo effects on pain provide a model for investigating how cognitive and contextual factors modulate the physiological processes underlying nociception and its regulation. However, existing accounts remain fragmented and lack a unifying mechanistic framework linking brain, behaviour and autonomic responses.
Zamfira DA, Fassina T, Zaworski K, Carlino E, Rossettini G.   +4 more
europepmc   +2 more sources

Optimal hepatobiliary scintigraphy for gallbladder dyskinesia

Surgery Open Science, 2021
Background: The accuracy of hepatobiliary scintigraphy to assess gallbladder function remains controversial. National supply shortages of pharmaceutical-grade cholecystokinin led to the use of an oral fatty meal to stimulate gallbladder contraction ...
K.F. Flick, MD, M. Soufi, MD, C.M. Sublette, BS, C.A. Sinsabaugh, MD, CL. Colgate, BS, M. Tann, MD, M.G. House, MD   +6 more
doaj   +1 more source

Autophagy, Acute Pancreatitis and the Metamorphoses of a Trypsinogen-Activating Organelle

Cells, 2022
Recent studies have highlighted the importance of autophagy and particularly non-canonical autophagy in the development and progression of acute pancreatitis (a frequent disease with considerable morbidity and significant mortality).
Svetlana Voronina, Michael Chvanov, Francesca De Faveri, Ulrike Mayer, Tom Wileman, David Criddle, Alexei Tepikin   +6 more
doaj   +1 more source

Administration of encapsulated L-tryptophan improves duodenal starch digestion and increases gastrointestinal hormones secretions in beef cattle [PDF]

Asian-Australasian Journal of Animal Sciences, 2020
Objective This study investigated the effects of oral administration of rumen-protected L-tryptophan (RPL-T) on duodenal starch digestion and gastrointestinal hormones (GIH) secretions using Hanwoo beef steers as the animal models.
Sang-Bum Lee, Kyung-Won Lee, Tao Wang, Jae-Sung Lee, U-Suk Jung, Jalil Ghassemi Nejad, Young-Kyoon Oh, Youl-Chang Baek, Kyoung Hoon Kim, Hong-Gu Lee   +9 more
doaj   +1 more source

Significance of the rs754635 variant of the cholecystokinin gene in the development of obesity in children

Сучасна педіатрія: Україна, 2023
So far, the possible influence of single nucleotide variants (SNV) of the cholecystokinin (CCK) gene on the likelihood of developing obesity and metabolic disorders in children has not been demonstrated.
A. Nikulina
doaj   +1 more source

A conserved neuropeptide system links head and body motor circuits to enable adaptive behavior

eLife, 2021
Neuromodulators promote adaptive behaviors that are often complex and involve concerted activity changes across circuits that are often not physically connected. It is not well understood how neuromodulatory systems accomplish these tasks.
Shankar Ramachandran, Navonil Banerjee, Raja Bhattacharya, Michele L Lemons, Jeremy Florman, Christopher M Lambert, Denis Touroutine, Kellianne Alexander, Liliane Schoofs, Mark J Alkema, Isabel Beets, Michael M Francis   +11 more
doaj   +1 more source

Neuropeptide System Regulation of Prefrontal Cortex Circuitry: Implications for Neuropsychiatric Disorders

Frontiers in Neural Circuits, 2022
Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate various biological effects including membrane excitability, synaptic transmission and synaptogenesis, gene expression, and glial cell architecture and function. To date,
Sanne M. Casello, Rodolfo J. Flores, Hector E. Yarur, Huikun Wang, Monique Awanyai, Miguel A. Arenivar, Rosario B. Jaime-Lara, Rosario B. Jaime-Lara, Hector Bravo-Rivera, Hugo A. Tejeda   +9 more
doaj   +1 more source