Results 31 to 40 of about 36,127 (235)
Proglumide analogues: potent cholecystokinin receptor antagonists [PDF]
Proglumide [N-(benzoyl)-L-glutamic acid-1-di-n-propylamide] is a specific cholecystokinin receptor antagonist. In the present study we synthesized various analogues of proglumide and used pancreatic acini from guinea pig pancreas to examine the ...
R. T. Jensen +6 more
core +1 more source
Cholecystokinin: A Key Integrator of Nutrient Assimilation [PDF]
Cholecystokinin regulates numerous gastrointestinal functions including pancreatic enzyme and fluid secretion and gastric emptying. Pleiotropic actions of cholecystokinin result in coordination of several aspects of ingestion, digestion, absorption, and
LD Lewis, JA Williams
core +1 more source
Cannabinoid CB1 Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity
Gut-brain signaling controls feeding behavior and energy homeostasis; however, the underlying molecular mechanisms and impact of diet-induced obesity (DIO) on these pathways are poorly defined.
Donovan A. Argueta +3 more
doaj +1 more source
Gastrin and cholecystokinin (CCK) are hormones released from endocrine cells in the antral stomach (gastrin), the duodenum, and the jejunum (CCK). Recent reports, based on secretion experiments in an enteroendocrine cell line (NCI‐H716) and gastrin ...
Ida M. Modvig +4 more
doaj +1 more source
Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice [PDF]
The aim of this study was to investigate the effect of long-term nutrient intake on the central response to the anorexigenic gut hormone CCK. C57BL/6 mice were fed one of three diets for 6 weeks: standard high carbohydrate (HC), high fat (HF), or high ...
Fromentin, G. +6 more
core +1 more source
Gut Hormones and Inflammatory Bowel Disease
Obesity-driven inflammation disrupts gut barrier integrity and promotes inflammatory bowel disease (IBD). Emerging evidence highlights gut hormones—including glucagon-like peptide-1 (GLP-1), glucagon-like peptide-2 (GLP-2), glucose-dependent ...
Jonathan Weng, Chunmin C. Lo
doaj +1 more source
Background There is conflicting data on the effects of carbon dioxide contained in beverages on stomach functions. We aimed to verify the effect of a pre-meal administration of a 300 ml non-caloric carbonated beverage (B+CO2) compared to water or a ...
Zito Francesco +10 more
doaj +1 more source
BRAIN CHOLECYSTOKININ SYSTEM IN NEUROTIC PATHOLOGY
Violation and discoordination of mental processes leads to changes in the ratio of the main neurotransmitters content and further to mental disorders. A significant role in such processes is played by neuropeptides, in particular anti-anxiety ones, which
R.V. Lutsenko +4 more
doaj +1 more source
Cholecystokinin-induced contraction of dispersed smooth muscle cells [PDF]
Isolated smooth muscle cells were prepared from the fundus of guinea pig stomach by incubation with collagenase. Incubating the cells with the C-terminal octapeptide of cholecystokinin induced contraction, which was measured by micrometry and expressed ...
S. M. Collins, J. D. Gardner
core +1 more source
Cholecystokinin-induced persistent stimulation of enzyme secretion from pancreatic acini [PDF]
When pancreatic acini are first incubated with cholecystokinin, washed to remove free cholecystokinin and then reincubated in fresh incubation solution, there is significant residual stimulation of amylase secretion.
R. T. Jensen +3 more
core +1 more source

