Results 1 to 10 of about 380,668 (238)
Carbohydrate inhibitors of cholera toxin [PDF]
Beilstein Journal of Organic Chemistry, 2018 Cholera is a diarrheal disease caused by a protein toxin released by Vibrio cholera in the host’s intestine. The toxin enters intestinal epithelial cells after binding to specific carbohydrates on the cell surface. Over recent years, considerable effort has been invested in developing inhibitors of toxin adhesion that mimic the carbohydrate ligand ...
Kumar, Vajinder, Turnbull, W Bruce
doaj +6 more sources
Cholera Toxin as a Probe for Membrane Biology. [PDF]
Toxins (Basel), 2021 Cholera toxin B-subunit (CTxB) has emerged as one of the most widely utilized tools in membrane biology and biophysics. CTxB is a homopentameric stable protein that binds tightly to up to five GM1 glycosphingolipids.
Kenworthy AK +6 more
europepmc +2 more sources
Advances in phage display based nano immunosensors for cholera toxin. [PDF]
Front Immunol, 2023 Cholera, a persistent global public health concern, continues to cause outbreaks in approximately 30 countries and territories this year. The imperative to safeguard water sources and food from Vibrio cholerae, the causative pathogen, remains urgent. The
Li Y, Yang KD, Kong DC, Ye JF.
europepmc +2 more sources
Neutralization of cholera toxin with nanoparticle decoys for treatment of cholera. [PDF]
PLoS Neglected Tropical Diseases, 2018 Diarrheal diseases are a major cause of morbidity and mortality worldwide. In many cases, antibiotic therapy is either ineffective or not recommended due to concerns about emergence of resistance.
Soumita Das +7 more
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Administration of novobiocin and apomorphine mitigates cholera toxin mediated cellular toxicity: Lessons from cholera toxin yeast model system. [PDF]
PLoS OneCholera is a dreadful disease. The scourge of this deadly disease is still evident in the developing world. Though several therapeutic strategies are in practice to combat and contain the disease, there is still a need for new drugs to control the ...
Bhalerao SE, Sen H, Raychaudhuri S.
europepmc +2 more sources
Vibrio mimicus Lineage Carrying Cholera Toxin and Vibrio Pathogenicity Island, United States and China. [PDF]
Emerg Infect DisVibrio mimicus bacteria have caused sporadic cases and outbreaks of cholera-like diarrhea throughout the world, but the association of lineages with such events is unexplored. Genomic analyses revealed V.
Morgado SM +3 more
europepmc +2 more sources
PLoS ONE, 2021 Infectious gastrointestinal diseases are frequently caused by toxins secreted by pathogens which may impair physiological functions of the intestines, for instance by cholera toxin or by heat-labile enterotoxin.
Pascal Hoffmann +6 more
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In-Depth Characterization of a Re-Engineered Cholera Toxin Manufacturing Process Using Growth-Decoupled Production in Escherichia coli. [PDF]
Toxins (Basel), 2022 Non-toxic derivatives of the cholera toxin are extensively used in neuroscience, as neuronal tracers to reveal the location of cells in the central nervous system.
Danielewicz N +7 more
europepmc +2 more sources
mBio, 2021 Cholera is still a massive global health burden because it causes large outbreaks with millions of infections and thousands of deaths every year. Several studies have contributed to the knowledge of this pathogen, although key parts are still missing ...
Franz G. Zingl +5 more
semanticscholar +1 more source
The Role of Vesicles in Transporting of Cholera Toxin
Проблемы особо опасных инфекций, 2023 The review reports on the secretion pathways of the main virulence factor of Vibrio cholerae, cholera toxin, both through the two-stage Sec-dependent type 2 secretion system and with the help of vesicles of the outer membrane of V. cholerae.
V. P. Zyuzina +4 more
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