Results 21 to 30 of about 77,065 (293)

Impact of solar irradiation on cholera toxin secretion by different strains of Vibrio cholerae

open access: yesSouth African Journal of Science, 2013
Cholera toxin is the aetiological agent of cholera – a deadly waterborne disease acquired through the consumption of untreated water contaminated with CTXФ bacteriophage harbouring strains of V. cholerae.
Cornelius C. Ssemakalu   +2 more
doaj   +1 more source

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network [PDF]

open access: yes, 2008
The small-molecule inhibitor Exo2 {4-hydroxy-3-methoxy-(5,6,7,8-tetrahydrol[1]benzothieno[2,3-d]pyrimidin-4-yl)hydraz-one benzaldehyde} has been reported to disrupt the Golgi apparatus completely and to stimulate Golgi–ER (endoplasmic reticulum) fusion ...
Aghi   +63 more
core   +5 more sources

High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence. [PDF]

open access: yesPLoS Pathogens, 2016
Cholera is the prime example of blood-group-dependent diseases, with individuals of blood group O experiencing the most severe symptoms. The cholera toxin is the main suspect to cause this relationship. We report the high-resolution crystal structures (1.
Julie Elisabeth Heggelund   +5 more
doaj   +1 more source

Retrograde transport pathways utilised by viruses and protein toxins [PDF]

open access: yes, 2006
A model has been presented for retrograde transport of certain toxins and viruses from the cell surface to the ER that suggests an obligatory interaction with a glycolipid receptor at the cell surface. Here we review studies on the ER trafficking cholera
Easton, A. J. (Andrew J.)   +4 more
core   +2 more sources

Ca2+-Stimulated Catecholamine Release from alpha-Toxin Permeabilized PC12 Cells [PDF]

open access: yes, 1987
Two possible cellular pathways of catecholamines from the chromaffin vesicles of PC 12 cells to the surrounding medium are explored in this study. The direct one circumventing the cytoplasm can be activated in a-toxin-permeabilized cells with micromolar ...
Ahnert-Hilger, G.   +2 more
core   +1 more source

Comparative Study of Xenobiotic-Free Media for the Cultivation of Human Limbal Epithelial Stem/Progenitor Cells. [PDF]

open access: yes, 2017
The culture of human limbal epithelial stem/progenitor cells (LSCs) in the presence of animal components poses the risk of cross-species contamination in clinical applications.
Chen, Luxia   +2 more
core   +1 more source

An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat [PDF]

open access: yes, 2015
In the absence of an ability to absorb fluid by cellular uptake mechanisms, fluid movement in vivo from the perfused rat intestine is absorptive when the diastolic blood pressure is normal or very low but is secretory when blood pressure falls below ...
Lucas, Michael, Morrison, James
core   +1 more source

The arteriolar vasodilatation model of vibrio cholerae induced diarrhoeal disease [PDF]

open access: yes, 2018
Secretory diarrhoeal disease caused by enterotoxins produced by pathogenic bacteria is characterised by severe fluid loss into the intestine. A prevalent explanation for such high rates of loss, such as occur in episodes of cholera, is that intestinal ...
Lucas, Michael
core   +1 more source

Subunit Structure of Cholera Toxin [PDF]

open access: yesJournal of General Microbiology, 1973
SUMMARY Two types of subunit, with molecular weights estimated to be 28000 and 8000, were demonstrated in the cholera exo-enterotoxin by sodium dodecylsulphate polyacrylamide electrophoresis. The light (L) component but not the heavy (H) was demonstrable in the antigenically identical natural toxoid.
I. Lönnroth, J. Holmgren
openaire   +3 more sources

Conservation of cholera toxin gene in a strain of cholera toxin non-producing Vibrio cholerae O1 [PDF]

open access: yesFEMS Microbiology Letters, 2006
BT23, a Vibrio cholerae O1 E1 Tor isolate, possesses the cholera toxin (CT) gene as determined by PCR. However, CT was not detected in the culture medium by the reversed passive latex agglutination test, nor in the whole cell lysate as examined by Western blotting. The toxin-coregulated pilus (TCP) was not detected by Western blotting.
Yasuko Honma, Masaaki Iwanaga
openaire   +3 more sources

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