A ‘catch-and-release’ receptor for the cholera toxin [PDF]
Faraday Discussions, 2019 Thermoresponsive receptors for the recognition unit of the cholera toxin (CTB) can recognise the protein with nanomolar affinity. An increase in temperature can drastically reduce their avidity, enabling on-demand release of CTB.
Michael E. Webb +9 more
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The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]
, 2007 Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Cheng Zhu +2 more
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Genomic epidemiology of Vibrio cholerae reveals the regional and global spread of two epidemic non-toxigenic lineages [PDF]
, 2020 Non-toxigenic Vibrio cholerae isolates have been found associated with diarrheal disease globally, however, the global picture of non-toxigenic infections is largely unknown. Among non-toxigenic V.
Cui, Yujun +10 more
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The hydrophobicities of cholera toxin, tetanus toxin and their components [PDF]
Biochemical Journal, 1981 1. Charge-shift electrophoresis showed that cholera toxin and its subunits have no hydrophobic surfaces. 2. Amino-acid composition and sequence data suggested that the proteins have no masked hydrophobic regions. 3. The A subunit of cholera toxin may interact with polar molecules in the membrane to exert its effect inside the cell. 4.
S van Heyningen, P Britton, Wally Ward
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Phenotypic and Genetic Analysis of Altered Variants of Vibrio cholerae Biovar El Tor
Проблемы особо опасных инфекций, 2012 Determined is cholera toxin production by altered Vibrio cholerae O1 eltor strains, isolated on the territory of Russia in 1993-2010, which contain classical type ctxB gene.
S. P. Zadnova +3 more
doaj +1 more source
The B subunit of Escherichia coli heat-labile toxin alters the development and antigen-presenting capacity of dendritic cells [PDF]
, 2015 Escherichia coli’s heat-labile enterotoxin (Etx) and its non-toxic B subunit (EtxB) have been characterized as adjuvants capable of enhancing T cell responses to co-administered antigen.
Griffiths, Kristin L. +4 more
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Enhanced sensitivity to cholera toxin in female ADP-ribosylarginine hydrolase (ARH1)-deficient mice.
PLoS ONE, 2018 Cholera toxin, an 84-kDa multimeric protein and a major virulence factor of Vibrio cholerae, uses the ADP-ribosyltransferase activity of its A subunit to intoxicate host cells.
Kizuku Watanabe +5 more
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Removal of Cholera Toxin from Aqueous Solution by Probiotic Bacteria
Pharmaceuticals, 2012 Cholera remains a serious health problem, especially in developing countries where basic hygiene standards are not met. The symptoms of cholera are caused by cholera toxin, an enterotoxin, which is produced by the bacterium <em>Vibrio cholerae< ...
Jussi A. O. Meriluoto +3 more
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Distinct role of clathrin-mediated endocytosis in the functional uptake of cholera toxin [PDF]
, 2007 The involvement of the clathrin-mediated endocytic internalization route in the uptake of cholera toxin (CT) was investigated using different cell lines, including the human intestinal Caco-2 and T84 cell lines, green monkey Vero cells, SH-SY5Y ...
De Wolf, Marc JS +2 more
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Advanced Healthcare Materials, EarlyView.A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim +12 more
wiley +1 more source