Results 81 to 90 of about 77,443 (276)

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin, Heloisa Amancio, Jessica Zablocki da Luz, Aliciane de Almeida Roque, Tugstênio Lima de Souza, José Eduardo Vargas, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +7 more
wiley   +1 more source

COMPARATIVE ANALYSIS OF TIGHT JUNCTIONS OF EPITHELIUM OF RATS JEJUNUM UNDER THE EFFECT OF LIPOPOLYSACCHARIDE AND CHOLERA TOXIN

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Comparative study of tight junctions and ultrastructure alterations of enterocytes of mucous membranes of jejunum of rats under the effect of lipopolysaccharides and cholera toxin. Materials and methods.
O. N. Vishnevskaya, O. V. Rybalchenko, I. V. Larionov, O. G. Orlova, A. G. Markov   +4 more
doaj   +1 more source

Enrichment of Hyaluronic Acid Binding Tumor Cells by Modulation of Selective Adhesion on Microgel Surfaces

Macromolecular Rapid Communications, EarlyView.
We have developed a thermoresponsive microgel system for the selective enrichment of hyaluronic acid‐binding tumor cells. By modulating the adhesion on the microgel surface via temperature changes from 37°C to 30°C, we demonstrate a novel proof‐of‐principle for separating these tumor cell from white blood cells, which has potential applications in ...
Melanie Schmidt, Dilay Karayel, André Franken, Janita Müller, Laura Hartmann, Klaus Pantel, Tanja Fehm, Hans Neubauer, Stephan Schmidt   +8 more
wiley   +1 more source

Enteropathogen antibody dynamics and force of infection among children in low-resource settings. [PDF]

, 2019
Little is known about enteropathogen seroepidemiology among children in low-resource settings. We measured serological IgG responses to eight enteropathogens (Giardia intestinalis, Cryptosporidium parvum, Entamoeba histolytica, Salmonella enterica ...
Arnold, Benjamin F, Cooley, Gretchen M, Costantini, Veronica, Goodhew, E Brook, Juma, Jane, Lammie, Patrick J, Martin, Diana L, Mkocha, Harran, Morris, Jamae F, Ochieng, John B, Omore, Richard, Priest, Jeffrey W, Vinjé, Jan   +12 more
core  

The Study of the Immune Layer to the Cholera Agent in Individuals Living in the Republic of Guinea

Проблемы особо опасных инфекций, 2019
For a reliable assessment of the presense of the immune layer to cholera agent, it is necessary to determine the level of specific antibodies in human blood serum.
D. V. Utkin, E. V. Naidenova, K. A. Nikiforov, A. V. Boiko, D. A. Agafonov, M. N. Lyapin, A. A. Lopatin, I. Bangoura, T. D. Camara, S. Boumbaly, M. Y. Boiro   +10 more
doaj   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Synthesis and Investigation of Apoptosis and Anti‐Metastatic Effects of Niosomes Containing the Extract of Colchicum kotschyi in MCF‐7

Natural Sciences, EarlyView.
This graphical abstract shows the synthesis and biological effects of niosomes loaded with Colchicum kotschyi extract on MCF‐7 breast cancer cells. The extract was encapsulated via the thin‐film hydration method to form stable, spherical niosomes. The formulation enhanced cytotoxicity, induced apoptosis, and suppressed metastasis by increasing Bax and ...
Mahsa Kavousi, Maryam Kazemi Hatami
wiley   +1 more source

Use of Magnetic Beads in Selection and Detection of Biotoxin Aptamers by Electrochemiluminescence and Enzymatic Methods

BioTechniques, 2002
Systematic evolution of ligands by exponential enrichment (SELEX) was used to develop DNA ligands (aptamers) to cholera whole toxin and staphylococcal enterotoxin B (SEB).
John G. Bruno, Johnathan L. Kiel
doaj   +1 more source

THE AESTHETICS OF URBAN METABOLISM: Landscape, Design and the Politics of In/Visibility

International Journal of Urban and Regional Research, EarlyView.
Abstract In this article, we chart the evolving aesthetic contours of urban metabolism across London, focusing on the River Lea and Thamesmead to the north and south of the River Thames, respectively. We begin in the nineteenth century, when these two sites formed critical nodes within a new sewerage system that relegated the city’s circulatory flows ...
Ben Platt, Zuhri James
wiley   +1 more source

Molecular insights into the evolutionary pathway of Vibrio cholerae O1 atypical El Tor variants.

PLoS Pathogens, 2014
Pandemic V. cholerae strains in the O1 serogroup have 2 biotypes: classical and El Tor. The classical biotype strains of the sixth pandemic, which encode the classical type cholera toxin (CT), have been replaced by El Tor biotype strains of the seventh ...
Eun Jin Kim, Dokyung Lee, Se Hoon Moon, Chan Hee Lee, Sang Jun Kim, Jae Hyun Lee, Jae Ouk Kim, Manki Song, Bhabatosh Das, John D Clemens, Jean William Pape, G Balakrish Nair, Dong Wook Kim   +12 more
doaj   +1 more source