Results 61 to 70 of about 27,709 (227)
Chronic Diseases and Translational Medicine, EarlyView.ABSTRACT The liver is increasingly recognized as a major regulator of systemic cardio‐renal‐metabolic health. Evidence is mounting that sex‐chromosome dosage per se itself, independent of gonadal sex hormones, modulates hepatic physiology and liver disease risk.
Mohamad Jamalinia +2 more
wiley +1 more source
Annals of Hepatology, 2010 Objective. Cystatin C is a very potent inhibitor of cysteine proteinases and, it has been clinically applied as a sensitive marker in monitoring of renal and liver functions.
Mehmet Buyukberber, Dr. +7 more
doaj +1 more source
A 19-year-old Patient with Recurrent Pruritus and Jaundice
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2023 Аim: to highlight the importance of broad differential diagnosis and possibility of conversion of benign recurrent intrahepatic cholestasis type 2 into more aggressive clinical phenotype.Key points. A 19-year-old female patient was admitted to the Clinic
K. S. Nezhdanov +5 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra +4 more
wiley +1 more source
Wellcome Open ResearchCholestasis is an impairment of bile formation or bile flow. The mechanisms of cholestasis can be broadly classified into intrahepatic and extrahepatic.
Janak Koirala +6 more
doaj +1 more source
The Role of Various Laboratory Parameters and Imaging Associated with Obstructive Jaundice in Cholangiocarcinoma [PDF]
, 2014 Cholangiocarcinoma is the second most common primary liver Malignancy with a global increase ofincidence and mortality. The mean age at presentation is 50 years.
Adiyanti, S. S. (Sri) +1 more
core +1 more source
Intrahepatic cholestasis of pregnancy : genetic background, epidemiology and hepatobiliary consequences [PDF]
, 2006 Intrahepatic cholestasis of pregnancy (ICP) is the most common cholestatic liver disease during pregnancy. The reported incidence varies from 0.4 to 15% of full-term pregnancies.
Ropponen, Anne
core
Biliary Anomalies in Patients With HNF1B Diabetes [PDF]
, 2017 Context: The clinical spectrum of organogenetic anomalies associated with HNF1B mutations is heterogeneous. Besides cystic kidney disease, diabetes, and various other manifestations, odd cases of mainly neonatal and posttransplantation cholestasis have ...
Färkkilä, Martti +7 more
core +1 more source
Novel diagnostic and prognostic biomarkers in biliary tract cancer. [PDF]
, 2013 The worldwide incidence of biliary tract carcinoma (BTC, tumours of the bile ducts and gall-bladder) continues to rise, with the only potentially curative treatment remaining surgical resection or transplantation, possible in only a minority of patients.
Pereira, SP, Skipworth, JR, Timms, JF
core +1 more source
Etiology and outcome of neonatal cholestasis: an experience in a tertiary center of Bangladesh
Egyptian Liver Journal, 2022 Background Neonatal cholestasis (NC) is a major cause of morbidity and mortality in young infants. This study examines the etiology of NC and its outcome during 2 years of follow-up at a tertiary referral center in Bangladesh.
Salavhuddin Mahmud +4 more
doaj +1 more source