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INTRAHEPATIC CHOLESTASIS OF PREGNANCY [PDF]
Intrahepatic cholestasis of pregnancy is one of the primary disorders of the liver that adversely affects maternal well-being and fetal outcome. Early identification of this condition, careful interdisciplinary monitoring, and prompt delivery at fetal maturity can improve outcomes in the mother and child.
openaire +3 more sources
Prevalence and Pregnancy Outcomes of Intrahepatic Cholestasis of Pregnancy
Background: Intrahepatic cholestasis of pregnancy is a common pregnancy-specific liver disease associated with increased risk of adverse fetal and maternal outcomes. We sought to determine its prevalence, risk factors and feto-maternal outcomes. Methods:
Deekshanta Sitaula +4 more
doaj +1 more source
The non-HDL-C to APOB ratio as a predictor of inaccurate LDL-C measurement in patients with chronic intrahepatic cholestasis and jaundice: a retrospective study [PDF]
Background Cholestasis is characterized by the accumulation of bile in the liver or biliary system due to obstruction or impaired flow, necessitating lipid profiling to assess lipid metabolism abnormalities.
Yongjiang Cheng +3 more
doaj +2 more sources
X-linked myotubular myopathy (XLMTM) is a rare, life-threatening congenital myopathy characterized by profound skeletal muscle weakness, respiratory distress, and motor dysfunction.
C. Molera +13 more
semanticscholar +1 more source
Alpha-1 Antitrypsin Z Variant (AAT PI*Z) as a Risk Factor for Intrahepatic Cholestasis of Pregnancy
Background: Intrahepatic cholestasis of pregnancy (ICP; prevalence 0.2–15.6%) is the most common pregnancy-related liver disorder. It may have serious consequences for a pregnancy, including increased risk of preterm delivery, meconium staining of ...
Przemyslaw Kosinski +12 more
doaj +1 more source
Evaluation of Plasma Lipid Levels in Intrahepatic Cholestasis of Pregnancy
Objective: To investigate the total cholesterol, triglyceride, LDL, VLDL, and HDL levels of pregnant women diagnosed with intrahepatic cholestasis of pregnancy and to examine the association with disease severity.
Şevki Çelen +2 more
doaj +1 more source
Intrahepatic cholestasis of pregnancy: risk factors for severe disease
Introduction Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-associated hepatic disorder characterized by pruritus in the setting of elevated serum bile acids (BA).
S. Mashburn +5 more
semanticscholar +1 more source
A child with debilitating pruritus
We describe a case of two-year-old boy presenting with debilitating pruritus, patchy alopecia and jaundice since the age of 6 months. On evaluation he had intrahepatic cholestasis with persistently raised serum alkaline phosphatase, normal Gamma glutamyl
Nikhil Sonthalia +7 more
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A homozygous R148W mutation in Semaphorin 7A causes progressive familial intrahepatic cholestasis
Semaphorin 7A (SEMA7A) is a membrane‐bound protein that involves axon growth and other biological processes. SEMA7A mutations are associated with vertebral fracture and Kallmann syndrome.
Qiong-Jing Pan +22 more
semanticscholar +1 more source
A metastatic disease causes jaundice is not uncommon and usually related to direct tumor invasion to the biliary tree or massive intrahepatic metastasis.
Essa A. Adawi
doaj +1 more source

