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Endothelial Function in Dyslipidemia: Roles of LDL-Cholesterol, HDL-Cholesterol and Triglycerides. [PDF]

Cells, 2023
Dyslipidemia is associated with endothelial dysfunction. Endothelial dysfunction is the initial step for atherosclerosis, resulting in cardiovascular complications.
Higashi Y.
europepmc   +2 more sources

Monocyte/high-density lipoprotein cholesterol, neutrophil/high-density lipoprotein cholesterol, and lymphocyte/high-density lipoprotein cholesterol ratios as new inflammatory markers in rosacea

Turkderm Turkish Archives of Dermatology and Venereology, 2023
Background and Design: Rosacea is a chronic inflammatory skin disease. The monocyte/high-density lipoprotein (HDL) cholesterol ratio (MHR), neutrophil/HDL cholesterol ratio (NHR), and lymphocyte/HDL cholesterol ratio (LHR) are new inflammatory parameters
Bülent Nuri Kalaycı
doaj   +1 more source

Impaired High‐Density Lipoprotein Function in Patients With Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background We recently showed that, in patients with heart failure, lower high‐density lipoprotein (HDL) cholesterol concentration was a strong predictor of death or hospitalization for heart failure.
Johanna E. Emmens, Congzhuo Jia, Leong L. Ng, Dirk J. van Veldhuisen, Kenneth Dickstein, Stefan D. Anker, Chim C. Lang, Gerasimos Filippatos, John G. F. Cleland, Marco Metra, Adriaan A. Voors, Rudolf A. de Boer, Uwe J. F. Tietge   +12 more
doaj   +1 more source

Low HDL Cholesterol Efflux Capacity Indicates a Fatal Course of COVID-19

Antioxidants, 2022
Plasma membrane cholesterol is required for proper trafficking and localization of receptors that facilitate severe acute respiratory syndrome coronavirus 2 infection.
Julia T. Stadler, Harald Mangge, Alankrita Rani, Pero Curcic, Markus Herrmann, Florian Prüller, Gunther Marsche   +6 more
doaj   +1 more source

Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]

, 2020
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui, Huang, Jiansheng, Huang, Li-Hao, Wang, Dongdong   +3 more
core   +2 more sources

Total cholesterol/HDL-cholesterol ratio discordance with LDL-cholesterol and non-HDL-cholesterol and incidence of atherosclerotic cardiovascular disease in primary prevention: The ARIC study

European Journal of Preventive Cardiology, 2020
Aims The total cholesterol (TC)/high-density lipoprotein (HDL) cholesterol ratio may carry additional information not available in more commonly used single cholesterol measures.
Renato Quispe, M. Elshazly, Di Zhao, P. Toth, R. Puri, S. Virani, R. Blumenthal, S. Martin, S. Jones, E. Michos   +9 more
semanticscholar   +1 more source

Effects of dalcetrapib in patients with a recent acute coronary syndrome [PDF]

, 2012
In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events.
Abt, Markus, Ballantyne, Christie M., Barter, Philip J., Brumm, Jochen, Chaitman, Bernard R., Colquhoun, David, Holme, Ingar M., Kallend, David, Leiter, Lawrence A., Leitersdorf, Eran, McMurray, John J. V., Mundl, Hardi, Nicholls, Stephen J., Olsson, Anders G., Schwartz, Gregory G., Shah, Prediman K., Tardif, Jean-Claude, The dal-OUTCOMES Investigators, Wright, R. Scott   +18 more
core   +2 more sources

GALNT2 mRNA levels are associated with serum triglycerides in humans [PDF]

, 2016
Atherogenic dyslipidemia, characterized by high triglycerides (TG) and low high density lipoprotein (HDL)-cholesterol levels, is a feature of patients with insulin resistance, obesity, and type 2 diabetes (T2D) [1] and plays a major role in shaping the ...
Di Paola, Rosa, Mangiacotti, Davide, Marucci, Antonella, TRISCHITTA, VINCENZO   +3 more
core   +1 more source

Associations of non-high-density lipoprotein cholesterol, triglycerides and the total cholesterol/HDL-c ratio with arterial stiffness independent of low-density lipoprotein cholesterol in a Chinese population

Hypertension Research, 2019
Several lipid parameters are closely associated with residual cardiovascular risk. We aimed to confirm that in a range of low-density lipoprotein cholesterol (LDL-c) levels (from
Jia Wen, Yun Huang, Yao Lu, Hong Yuan
semanticscholar   +1 more source

Cholesterol efflux by acute-phase high density lipoprotein: role of lecithin:cholesterol acyltransferase1

Journal of Lipid Research, 2001
HDL plays an initial role in reverse cholesterol transport by mediating cholesterol removal from cells. During infection and inflammation, several changes in HDL composition occur that may affect the function of HDL; therefore, we determined the ability ...
Weerapan Khovidhunkit, Judy K. Shigenaga, Arthur H. Moser, Kenneth R. Feingold, Carl Grunfeld   +4 more
doaj   +1 more source