Results 31 to 40 of about 15,742 (75)
Bifurcation for a free boundary problem modeling a small arterial plaque [PDF]
arXiv, 2020 Atherosclerosis, hardening of the arteries, originates from small plaque in the arteries; it is a major cause of disability and premature death in the United States and worldwide. In this paper, we study the bifurcation of a highly nonlinear and highly coupled PDE model describing the growth of arterial plaque in the early stage of atherosclerosis. The
arxiv
Jurnal Farmasi Sains dan Komunitas, 2017 Cardiovascular disease is the number one cause of death in the world. The diseaseis influenced by several factors such as lack of physical activity, imbalanced nutritional intake, and high blood cholesterol levels.
Utari Febrina Supomo Sunu +2 more
doaj +1 more source
On the first bifurcation point for a free boundary problem modeling small arterial plaque [PDF]
arXiv, 2020 Atherosclerosis occurs when plaque clogs the arteries. It is a leading cause of death in the United States and worldwide. In this paper, we study the bifurcation for a highly nonlinear and highly coupled PDE model of plaque formation in the early stage of atherosclerosis.
arxiv
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
Loci controlling plasma non-HDL and HDL cholesterol levels in a C57BL /6J × CASA /Rk intercross
Journal of Lipid Research, 2003 Plasma non-HDL and HDL cholesterol levels are predictors of cardiovascular diseases. We carried out a genetic cross between two laboratory inbred mouse strains, C57BL/6J and CASA/Rk, to detect loci that control the plasma levels of non-HDL and HDL ...
Ephraim Sehayek +4 more
doaj
US Cardiology Review, 2019 Despite historical evidence suggesting an inverse association between HDL cholesterol (HDL-C) and adverse cardiovascular events, pharmacological efforts to increase HDL-C and improve outcomes have not been successful.
Marc P Allard-Ratick +3 more
doaj +1 more source
Mendelian Randomization when Many Instruments are Invalid: Hierarchical Empirical Bayes Estimation [PDF]
arXiv, 2017 Estimating the causal effect of an exposure on an outcome is an important task in many economical and biological studies. Mendelian randomization, in particular, uses genetic variants as instruments to estimate causal effects in epidemiological studies.
arxiv
Raft-like domain formation in model lipid-cholesterol aggregation [PDF]
arXiv, 2020 To understand mechanism of cell-membrane compartmentalization, we studied coarse-grained model systems consisting of lipid and cholesterol molecules. Cholesterol plays crucial role in lateral phase segregation in the bilayered lipid membrane to form cholesterol rich liquid ordered domains, termed as `rafts'.
arxiv
Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo
Journal of Lipid Research, 2009 Uptake of cholesterol from peripheral cells by nascent small HDL circulating in plasma is necessary to prevent atherosclerosis. This process, termed reverse cholesterol transport, produces larger cholesterol-rich HDL that transfers its cholesterol to the
Frank M. Sacks +13 more
doaj
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground The cholesterol efflux capacity of high density lipoprotein (HDL) is negatively associated with cardiovascular risk. Small HDL particles account almost quantitatively for cholesterol efflux capacity, perhaps mediated through efflux of ...
Tina Costacou +6 more
doaj +1 more source