Results 41 to 50 of about 15,742 (75)
Lessons of Slicing Membranes: Interplay of Packing, Free Area, and Lateral Diffusion in Phospholipid/Cholesterol Bilayers [PDF]
We employ 100 ns molecular dynamics simulations to study the influence of cholesterol on structural and dynamic properties of dipalmitoylphosphatidylcholine (DPPC) bilayers in the fluid phase. The effects of the cholesterol content on the bilayer structure are considered by varying the cholesterol concentration between 0 and 50%.
arxiv +1 more source
Nanoparticle charge-transfer interactions induce surface dependent conformational changes in apolipoprotein biocorona [PDF]
Upon introduction into a biological system, engineered nanomaterials (ENMs) rapidly associate with a variety of biomolecules such as proteins and lipids to form a biocorona. The presence of biocorona influences nano-bio interactions considerably, and could ultimately result in altered biological responses.
arxiv
Hepatic lipase stimulates the uptake of high density lipoprotein cholesterol by hepatoma cells.
The objective of this study was to determine whether high density lipoproteins (HDL) that have been treated with hepatic lipase have an enhanced ability to deliver cholesterol to cells.
M Bamberger, J M Glick, G H Rothblat
doaj
Control of rodent sleeping sickness disease by surface functionalized amorphous nanosilica [PDF]
Wild animals, pets, zoo animals and mammals of veterinary importance heavily suffer from trypanosomiasis. Drugs with serious side effects are currently mainstay of therapies used by veterinarians. Trypanosomiasis is caused by Trypanosoma sp. leading to sleeping sickness in humans.
arxiv
Recently, we showed that holo HDL particle uptake and resecretion occur in physiologically relevant cell lines and that HDL uptake is mediated by scavenger receptor class B type I (SR-BI).
Tamara A. Pagler+4 more
doaj
Background: The pathophysiology of polycystic ovary syndrome (PCOS) is complex and heterogeneous. This systematic review and meta-analysis aimed to determine the triglyceride–glucose index and lipid ratios in women with and without PCOS.
Juan R. Ulloque-Badaracco+11 more
doaj +1 more source
Ruo-Nan Tian,1,2 Sheng-Xiao Zhang,2– 5 Nan Zhang,6 Yan Shi,1 Hua-Qing Guo,1 Chen Wang,1 Zhi-Guang Duan6 1College of Humanities and Social Sciences, Shanxi Medical University, Taiyuan, Shanxi, 030001, People’s Republic of China; 2Key Laboratory of ...
Tian RN+6 more
doaj
Powerful genome-wide design and robust statistical inference in two-sample summary-data Mendelian randomization [PDF]
Two-sample summary-data Mendelian randomization (MR) has become a popular research design to estimate the causal effect of risk exposures. With the sample size of GWAS continuing to increase, it is now possible to utilize genetic instruments that are only weakly associated with the exposure.
arxiv
Lipid Abnormalities Associated With Stroke
Association of dyslipidemia with stroke is conflicting though recent studies point to their positive role. Sixty consecutive patients with stroke were analyzed for fasting lipid profile values.
Thacker Anup K+3 more
doaj
Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein
Transintestinal cholesterol efflux (TICE) provides an attractive target to increase body cholesterol excretion. At present, the cholesterol donor responsible for direct delivery of plasma cholesterol to the intestine is unknown.
Carlos L.J. Vrins+11 more
doaj