Results 141 to 150 of about 25,663 (167)

Antiviral role of cholesterol 25-hydroxylase in inhibiting porcine circovirus 3 replication

Veterinary Microbiology
Cholesterol 25-hydroxylase (CH25H) has significant antiviral effects through the production of 25-hydroxycholesterol (25HC). In this study, we investigated the effects of CH25H, its catalytic product 25HC, and its catalytic mutant lacking hydroxylase activity (CH25H-M) on porcine circovirus 3 (PCV3) replication.
Baoge, Zhang, Lumen, Chao, Zhendong, Wang, Hao, Yu, Yufeng, Li   +4 more
openaire   +2 more sources

Suppression of Monkeypox Virus by Downregulation of Fatty Acid Synthase and Upregulation of Cholesterol‐25 Hydroxylase

Journal of Medical Virology
ABSTRACTThe World Health Organization declared the spread of monkeypox virus (MPXV) across multiple African countries a public health emergency of international concern in August 2024. This marks the second such declaration in the past 2 years in response to the MPXV transmission.
Saba R. Aliyari, Jean Shanaa, Daniel Yu, Mari Yamamoto, Kaitlyn N. Bateman, Lulan Wang, Michael E. Jung, Genhong Cheng   +7 more
openaire   +3 more sources

Anticonvulsive properties of soticlestat, a novel cholesterol 24‐hydroxylase inhibitor

Epilepsia, 2022
Toshiya Nishi, Cameron S Metcalf, Shinji Fujimoto   +2 more
exaly  

Investigating the Mechanisms of Cholesterol 25-Hydroxylase in Promoting Pulmonary Fibrosis

Pulmonary fibrosis is a chronic and fatal disease characterized by progressive lung scarring. In many cases, its etiology is not fully understood, and treatment options are limited due to the complexity of profibrotic signaling pathways and the interplay between multiple cell types involved in the pathogenesis.
openaire   +1 more source

The role of cholesterol 25-hydroxylase in viral infections in zebrafish

Fish & Shellfish Immunology
Justyna Starzyk, Artem Voitsekhovskyi, Maria Zawisza, Niedharsan Pooranachandran, Alberto Falco, Win Surachetpong, Magdalena Chadzinska, Mikołaj Adamek, Krzysztof Rakus   +8 more
openaire   +1 more source

Cafestol, the Cholesterol-Raising Factor in Boiled Coffee, Suppresses Bile Acid Synthesis by Downregulation of Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase in Rat Hepatocytes

Arteriosclerosis, Thrombosis, and Vascular Biology, 1997
Sabine M Post, Hans M G Princen
exaly  

Alternate pathways of bile acid synthesis in the cholesterol 7α-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding

Journal of Lipid Research, 2001
Margrit Schwarz, David W Russell, John M Dietschy   +2 more
exaly  

Cholesterol 25-hydroxylase

2009
openaire   +1 more source

An improved method for assay of cholesterol 7α-hydroxylase activity

Analytical Biochemistry, 1986
Tadashi Ogishima, Kyuichiro Okuda
exaly  

Assay of cholesterol 7α-hydroxylase activity in rat hepatocytes in primary monolayer culture

Analytical Biochemistry, 1988
Hans M G Princen, Jaap Kwekkeboom, H J Kempen   +2 more
exaly