Results 131 to 140 of about 25,663 (167)

Real-world use of HIF-PH inhibitors in the Japan dialysis and practice patterns study (J-DOPPS, 2019-2022). [PDF]

BMC Nephrol
Eriguchi M, Tsuruya K, Noma H, Onishi Y, Inuzuka M, Harada K, Nangaku M.   +6 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

The role of cholesterol 25-hydroxylase in viral infections: Mechanisms and implications

Pathology - Research and Practice, 2023
Viral infections pose significant threats to human health, causing various diseases with varying severity. The intricate interactions between viruses and host cells determine the outcome of infection, including viral replication, immune responses, and disease progression.
Parastoo Yousefi, Ali Gholami, Mohsen Mehrjo, Mohammad Hossein Razizadeh, Mandana Akhavan, Sajad Karampoor, Alireza Tabibzadeh   +6 more
openaire   +2 more sources

Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms

Veterinary Microbiology, 2021
Cholesterol 25-hydroxylase (CH25 H), as a host restriction factor, has been reported to take a broad-spectrum antiviral effect. However, the role of CH25H in Senecavirus A (SVA) infection remains unknown. In this study, we first demonstrate that overexpression of CH25H inhibits SVA replication.
Huixin, Zhu, Junfang, Yan, Xing, Liu, Liang, Li, Wenwen, Liu, Xianwei, Wang, Ping, Jiang, Juan, Bai   +7 more
openaire   +2 more sources

CYP109E1 from Bacillus megaterium Acts as a 24‐ and 25‐Hydroxylase for Cholesterol

ChemBioChem, 2019
AbstractIn this study, the ability of CYP109E1 from Bacillus megaterium DSM319 to metabolize cholesterol was investigated. This steroid was identified as a new substrate to be converted by CYP109E1 with adrenodoxin and adrenodoxin reductase as redox partners in vitro.
Natalia Putkaradze, Martin Litzenburger, Michael Christopher Hutter, Rita Bernhardt   +3 more
openaire   +2 more sources

Cholesterol 25-hydroxylase suppresses rabies virus infection by inhibiting viral entry

Archives of Virology, 2019
Cholesterol-25-hydroxylase (CH25H) is a reticulum-associated membrane protein that catalyzes the oxidation of cholesterol to 25-hydroxycholesterol (25HC). Recent studies have revealed that CH25H is an interferon-stimulated gene (ISG) that suppresses infection by several viruses.
Yueming Yuan, Zongmei Wang, Bin Tian, Ming Zhou, Zhen F. Fu, Ling Zhao   +5 more
openaire   +2 more sources

Role of cholesterol 25 hydroxylase in fibrotic posterior capsular opacification

2020
Posterior capsular opacification (PCO), a common fibrotic complication of cataract surgery, is a disease which arises from epithelial to mesenchymal transition (EMT) of residual lens epithelial cells (LECs) within the lens capsule. The cells migrate toward the posterior capsule and form scar tissue, obstructing the visual axis and forming a secondary ...
openaire   +2 more sources

Regulation of cholesterol 25-hydroxylase expression by vitamin D3 metabolites in human prostate stromal cells

Biochemical and Biophysical Research Communications, 2006
Vitamin D3 plays an important role in the control of cell proliferation and differentiation. Cholesterol 25-hydroxylase (CH25H) is an enzyme converting cholesterol into 25-hydroxycholesterol. Vitamin D3 as well as 25-hydroxycholesterol has been shown to inhibit cell growth and induce cell apoptosis.
Jing-Huan, Wang, Pentti, Tuohimaa
openaire   +2 more sources

Cholesterol 25-hydroxylase inhibits encephalomyocarditis virus replication through enzyme activity-dependent and independent mechanisms

Veterinary Microbiology, 2020
Cholesterol-25-hydroxylase (CH25 H) is a reticulum-associated membrane protein induced by an important interferon-stimulating gene (ISG) and can significantly inhibit some virus replication. But the effect of CH25H on encephalomyocarditis virus (EMCV) is still not clear. In this study, we found that EMCV infection increases significantly the endogenous
Shihai, Li, Liang, Li, Huixin, Zhu, Mengyu, Shi, Hui, Fan, YanNi, Gao, XianWei, Wang, Ping, Jiang, Juan, Bai   +8 more
openaire   +2 more sources