Results 111 to 120 of about 6,635 (224)

Disrupted coordinate regulation of farnesoid X receptor target genes in a patient with cerebrotendinous xanthomatosis

Journal of Lipid Research, 2005
Cerebrotendinous xanthomatosis (CTX), sterol 27-hydroxylase (CYP27A1) deficiency, is associated with markedly reduced chenodeoxycholic acid (CDCA), the most powerful activating ligand for farnesoid X receptor (FXR). We investigated the effects of reduced
Akira Honda, Gerald Salen, Yasushi Matsuzaki, Ashok K. Batta, Guorong Xu, Takeshi Hirayama, G. Stephen Tint, Mikio Doy, Sarah Shefer   +8 more
doaj   +1 more source

Oxysterol 7α-Hydroxylase Activity by Cholesterol 7α-Hydroxylase (CYP7A) [PDF]

, 2000
Maria Norlin, Jan Andersson, Ingemar Björkhem, Kjell Wikvall   +3 more
openalex   +1 more source

Formation and metabolism in vitro of 5,6-epoxides of cholesterol and β-sitosterol

Journal of Lipid Research, 1974
The formation of 5α,6α- and 5β,6β-epoxides of cholesterol and β-sitosterol in rat liver subcellular fractions has been studied. The results show that the epoxidation seems to occur only in connection with the nonspecific tissue oxidation of the sterols ...
Leif Aringer, Peter Eneroth
doaj   +1 more source

Tissue dyslipidemia in salmonella-infected rats treatTissue dyslipidemia in salmonella-infected rats treated with amoxillin and pefloxac [PDF]

, 2012
Background: This study investigated the effects of salmonella infection and its chemotherapy on lipid metabolism in tissues of rats infected orally with Salmonella typhimurium and treated intraperitoneally with pefloxacin and amoxillin.
Chaichoompu, K, Chareanchim, W, Fouladi, R, Sakuntabhai, A, Tongsima, S, Van Steen, Kristel, Wangkumhang, P, Wilantho, A   +7 more
core   +1 more source

Farnesoid X Receptor Responds to Bile Acids and Represses Cholesterol 7α-Hydroxylase Gene (CYP7A1) Transcription [PDF]

, 2000
John Y.L. Chiang, Rhonda Kimmel, Cary Weinberger, Diane Stroup   +3 more
openalex   +1 more source

Intrahepatic cholestasis of pregnancy : genetic background, epidemiology and hepatobiliary consequences [PDF]

, 2006
Intrahepatic cholestasis of pregnancy (ICP) is the most common cholestatic liver disease during pregnancy. The reported incidence varies from 0.4 to 15% of full-term pregnancies.
Ropponen, Anne
core  

Exploring the Effects of Metabolites from Lactobacillus rhamnosus GM020 and Cyanidin-3-O-Glucoside on Differential Metabolites in the High-fat Diet Mice Liver Based on Metabolomics

Shipin gongye ke-ji
Objective: Investigating the regulatory effects of cyanidin-3-O-glucoside (C3G) and Lactobacillus rhamnosus GM020 metabolite (C3G-GM020) on cholesterol metabolism in high-fat diet-fed mice using untargeted metabolomics.
Sihang WANG, Bin LI, Hui TAN, Xianjun MENG, Yongping XU, Shuying LI, Xiaoru LIU, Yuehua WANG, Yan MA   +8 more
doaj   +1 more source

Regulation of the Human Cholesterol 7α-Hydroxylase Gene (CYP7A1) by Thyroid Hormone in Transgenic Mice [PDF]

, 2003
Victor A. Drover, Luis B. Agellon
openalex   +1 more source

Partial Purification and Characterization of Cholesterol 7α-Hydroxylase from Guinea Pig [PDF]

, 1987
Cholesterol 7α-hydroxylase (cholesterol, NADPH: oxygen oxidoreductase, 7α-xhydroxylating, EC 1.14.13.17), was partially purified from liver microsomes of guinea pig. The purified sample showed a specific activity of 1.
NAKAI, Taketomi
core  

Hypocholesterolemic Mechanism ofChlorella:Chlorellaand Its Indigestible Fraction Enhance Hepatic Cholesterol Catabolism through Up-Regulation of Cholesterol 7α-Hydroxylase in Rats [PDF]

, 2007
Shinya Shibata, Kazuhito Hayakawa, Yukari Egashira, Hiroo Sanada   +3 more
openalex   +1 more source