Results 181 to 190 of about 636,959 (293)

METTL16 Promotes Head and Neck Squamous Cell Carcinoma Progression via m6A-Mediated Stabilization of SREBP2 mRNA and Enhanced Cholesterol Biosynthesis. [PDF]

Cancer Med
Ma X, Ding X, Deng J, Gao Q, Liu H, Yuan S, Xiao Z, Jiang R.   +7 more
europepmc   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Corrigendum to "NUDT21-mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression". [PDF]

Adv Sci (Weinh)
europepmc   +1 more source

CD79A/CD40 intracellular domain uses a 4-1BB-like metabolic pathway driven by cholesterol biosynthesis. [PDF]

J Immunother Cancer
Takeuchi Y, Terakura S, Ishigiwa K, Julamanee J, Hirano S, Yokota H, Kuwano S, Hanajiri R, Kiyoi H.   +8 more
europepmc   +1 more source

The Utilization of Squalene in the Biosynthesis of Cholesterol

Journal of Biological Chemistry, 1953
R G, LANGDON, K, BLOCH
openaire   +2 more sources

Decoding the Gut‐Brain Axis: Multi‐Omics Reveals a Causal Chain Linking Human Genome, Gut Microbiota, Blood Metabolites, and Alertness in the Brain

Med Research, EarlyView.
This multi‐omics study identified genetic loci, gut microbiota, blood metabolites, and gray matter volumes of orbitofrontal cortex and cerebellum that were potentially relevant to alerting in healthy Chinese adults. Subsequent two‐step one‐sample Mendelian randomization further revealed a serial mediation pathway: Bacteroides intestinalis influences ...
Hongru Li, Chuansheng Chen, Ofir Turel, Yu Pu, Hong Chen, Tingyong Feng, Jiang Qiu, Xu Lei, Qinghua He   +8 more
wiley   +1 more source

NUDT21-mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression. [PDF]

Adv Sci (Weinh)
Yu Y, Ma J, Zhou M, Gu X, Zhou Y, Li Z, Zhang T, Gong W, Huang C, Xiang J.   +9 more
europepmc   +1 more source

TERPENOID INTERMEDIATES IN THE BIOSYNTHESIS OF CHOLESTEROL

Journal of Biological Chemistry, 1956
F, DITURI, F A, COBEY, J V, WARMS, S, GURIN   +3 more
openaire   +2 more sources

The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease

Pediatric Investigation, EarlyView.
Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia, Xiaolin Ye, Zhaoxia Wang, Jie Wu   +3 more
wiley   +1 more source

RhoE downregulation leads to enhanced cholesterol biosynthesis and sorafenib resistance in hepatocellular carcinoma. [PDF]

J Biol Chem
Feng J, Ye L, Chen C, Zhu Y, Liu R, Yu H, Lu L, Gong K, Li W.   +8 more
europepmc   +1 more source