Results 201 to 210 of about 636,959 (293)

Pulsed electromagnetic stimulation promotes neuronal maturation by up-regulating cholesterol biosynthesis. [PDF]

Stem Cell Res Ther
Chen P, Li J, Telezhkin V, Gu Y, Tao M, Guo L, Song S, Dong R, Luo X, Wang Y, Liu Q, Tian W, Meng W, Hong W, Song B.   +14 more
europepmc   +1 more source

Lipoproteins and cholesterol: Biosynthesis and metabolism

The Journal of the American Osteopathic Association, 1988
openaire   +2 more sources

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Suppression of PKM2 by Leonurine Attenuates Alcoholic Hepatitis Through Regulating Glycolytic Reprogramming

Phytotherapy Research, EarlyView.
Leonurine inhibits PKM2 to remodel hepatocyte glycolysis, thereby alleviating liver injury in alcoholic hepatitis. ABSTRACT Alcoholic hepatitis (AH) is a liver disease caused by long‐term heavy drinking. In the early stages, it usually manifests as fatty liver, which can then develop into liver fibrosis and cirrhosis.
Xuan‐Xuan Zhang, Gao‐Feng Pan, Hong Fang, Xiao‐Peng Liu, Jing Sun, Ji‐Xiang Chen, Xin Fan, Jia‐Hao Feng   +7 more
wiley   +1 more source

Lycorine hydrochloride inhibits cholangiocarcinoma through cholesterol biosynthesis and PTPN11 nuclear translocation. [PDF]

Cell Commun Signal
Zhao F, Peng S, Zou L, Zhong M, Huang Y, Wang P, Ji M, Ma X, Li F.   +8 more
europepmc   +1 more source

Ajugol Improves Liver Fibrosis by Modulating Bile Acid and Arachidonic Acid Metabolism in Mice

Phytotherapy Research, EarlyView.
Ajujol ameliorates hepatic fibrosis by regulating bile acid metabolism and suppressing inflammatory responses. ABSTRACT Ajugol (AJ), the primary component extracted from the root of Rehmannia glutinosa, exhibits protective effects against metabolic dysregulation and chronic inflammation.
Xia Wei, Fangyuan Wang, Dingqi Zhang, Longhui Zhang, Feipeng Xu, Gaofeng Chen, Hua Zhang, Ping Liu, Wei Liu, Ying Xu   +9 more
wiley   +1 more source

Harnessing m⁶A-regulated cholesterol biosynthesis helps impede tumor burden and stemness in high-garde serous ovarian carcinoma mesenchymal phenotype. [PDF]

Mol Med
Narayanan A, Dhenge K, Bapat SA.
europepmc   +1 more source

Magnoflorine Ameliorates MASH in Mice Fed a High‐Fat and High‐Fructose Diet by Promoting AMPK‐Mediated Lipophagy and Fatty Acid Oxidation

Phytotherapy Research, EarlyView.
Magnoflorine ameliorates metabolic dysfunction‐associated steatohepatitis by promoting AMPKα‐mediated lipophagy and fatty acid oxidation. ABSTRACT Emerging as a significant clinical burden, metabolic dysfunction‐associated steatohepatitis (MASH) continues to challenge global healthcare systems due to limited effective interventions.
Zhengjie Lu, Tongyun Mao, Longxin Chai, Kaiqi Chen, Kexin Liu, Cong Zhang, Hao Kou   +6 more
wiley   +1 more source

<i>ACTA2</i> Pathogenic Variants Activating Heat Shock Factor 1 and Increasing Cholesterol Biosynthesis in Smooth Muscle Cells Predispose to Early Onset Atherosclerosis. [PDF]

Circ Genom Precis Med
Boerio ML, Chattopadhyay A, Duan XY, Karla A, Calderon Martinez E, Pinard A, Morse AK, Reddy D, Dharma S, Velasco-Torrez W, Marcadier J, Prakash SK, Shalhub S, De Backer J, Jeremy R, Morris SA, Yetman AT, Braverman AC, Milewicz DM.   +18 more
europepmc   +1 more source

Emerging Approaches for Phytoconstituent Delivery in the Management of Rheumatoid Arthritis: Bridging Nature and Nanotechnology

Phytotherapy Research, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is an autoimmune condition marked by joint inflammation, cartilage destruction, and bone damage. Conventional treatments, including NSAIDs and DMARDs, have shown effectiveness in slowing down disease progression, but prolonged exposure to such medications results in adverse effects and lack of tolerance among patients.
Yogesh Khairnar, Sakshi Priya, Madhavi Rajpara, Venkatesh K. P. Rao, Geeta Bhatt, Gautam Singhvi   +5 more
wiley   +1 more source