Results 41 to 50 of about 50,237 (296)

Cholesterol efflux from cells enriched with cholesteryl esters by incubation with hypercholesterolemic monkey low density lipoprotein

Journal of Lipid Research, 1983
The mass efflux of free and esterified cholesterol was studied in skin fibroblasts loaded with cholesterol by incubation with low density lipoproteins (LDL) isolated from normal or hypercholesterolemic cynomolgus monkeys.
R W St Clair, M A Leight
doaj   +1 more source

Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]

, 2011
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu, Frazer J. Rixon, Petermann, P., Rixon Frazer J., Rahn, E., Hsu Mei-Ju, Knebel-Mörsdorf, D., Geraghty, R.J., Dagmar Knebel-Mörsdorf, Rahn Elena, Philipp Petermann, Knebel-Mörsdorf Dagmar, Elena Rahn, Frazer J Rixon, Hsu, M.-J., Rixon, F.J., Petermann Philipp   +16 more
core   +1 more source

Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

Journal of Lipid Research, 2015
The ability of HDL to support macrophage cholesterol efflux is an integral part of its atheroprotective action. Augmenting this ability, especially when HDL cholesterol efflux capacity from macrophages is poor, represents a promising therapeutic strategy.
Andrea J. Luthi, Nicholas N. Lyssenko, Duyen Quach, Kaylin M. McMahon, John S. Millar, Kasey C. Vickers, Daniel J. Rader, Michael C. Phillips, Chad A. Mirkin, C.Shad Thaxton   +9 more
doaj   +1 more source

Reverse Cholesterol Transport Pathway and Cholesterol Efflux in Diabetic Retinopathy [PDF]

Journal of Diabetes Research, 2021
Cholesterol esters, synthesized from cholesterol with long-chain fatty acids, are essential components of plasma lipoproteins and cell membranes that participate in various metabolic processes in the body. Cholesterol can be excreted through the cholesterol reverse transport (RCT) pathway when excessive cholesterol is produced in the extrahepatic cells,
Xinyuan Zhang, Kaiyue Wang, Ling Zhu, Qiyun Wang   +3 more
openaire   +3 more sources

Importance of macrophage cholesterol content on the flux of cholesterol mass

Journal of Lipid Research, 2010
Net flux of cholesterol represents the difference between efflux and influx and can result in net cell-cholesterol accumulation, net cell-cholesterol depletion, or no change in cellular cholesterol content.
Sandhya Sankaranarayanan, Margarita de la Llera-Moya, Denise Drazul-Schrader, Bela F. Asztalos, Ginny L. Weibel, George H. Rothblat   +5 more
doaj   +1 more source

Predictive value of HDL function in patients with coronary artery disease: relationship with coronary plaque characteristics and clinical events

Annals of Medicine, 2022
Background HDL is endowed with several metabolic, vascular, and immunoinflammatory protective functions. Among them, a key property is to promote reverse cholesterol transport from cells back to the liver.
Marco Magnoni, Daniele Andreini, Angela Pirillo, Patrizia Uboldi, Roberto Latini, Alberico L. Catapano, Aldo P. Maggioni, Giuseppe D. Norata   +7 more
doaj   +1 more source

Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages

Journal of Lipid Research, 2019
Sphingolipid and cholesterol metabolism are closely associated at the structural, biochemical, and functional levels. Although HDL-associated sphingosine-1-phosphate (S1P) contributes to several HDL functions, and S1P signaling regulates glucose and ...
Mithila Vaidya, Julian A. Jentsch, Susann Peters, Petra Keul, Sarah Weske, Markus H. Gräler, Emil Mladenov, George Iliakis, Gerd Heusch, Bodo Levkau   +9 more
doaj   +1 more source

Cellular cholesterol efflux in diabetes mellitus [PDF]

, 2016
Cellular cholesterol efflux is the first step of the reverse cholesterol transport pathway that transfers extrahepatic cholesterol to the liver for further metabolism.
Tsun, Gar-shun, 秦嘉信
core   +1 more source

Macrophage cholesterol efflux correlates with lipoprotein subclass distribution and risk of obstructive coronary artery disease in patients undergoing coronary angiography

Lipids in Health and Disease, 2009
Background Studies in patients with low HDL have suggested that impaired cellular cholesterol efflux is a heritable phenotype increasing atherosclerosis risk.
Kremer Werner, Huber Fritz, Lieb Wolfgang, Mayer Björn, Belz Stefanie, Aherrarhou Zouhair, Jansen Henning, Linsel-Nitschke Patrick, Kalbitzer Hans-Robert, Erdmann Jeanette, Schunkert Heribert   +10 more
doaj   +1 more source

Cholesterol efflux from macrophages. [PDF]

, 2015
J774 macrophages enriched with 3H-cholesterol were incubated with apoA-I WT or A164S and cholesterol efflux quantified as a function of protein concentration (A) or time (B) by scintillation counting of the resulting treatment media.
Jitka Petrlova (131452), Jens O. Lagerstedt (297275), Jonathan Dalla-Riva (587369)   +2 more
core   +1 more source