Results 31 to 40 of about 53,815 (207)

The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans [PDF]

, 1997
Cafestol and kahweol–diterpenes present in unfiltered coffee— strongly raise serum VLDL and LDL cholesterol and slightly reduce HDL cholesterol in humans. The mechanism of action is unknown.
Gent, T. van, Jong-Caesar, R. de, Katan, M.B., Roos, B. de, Scheek, L. M., Tol, A. van, Urgert, R.   +6 more
core   +3 more sources

Association of cholesteryl ester transfer protein with HDL particles reduces its proteolytic inactivation by mast cell chymase

Journal of Lipid Research, 2008
Human atherosclerotic intima contains mast cells that secrete the neutral protease chymase into the intimal fluid, which also contains HDL-modifying proteins, such as cholesteryl ester transfer protein (CETP), in addition to abundant amounts of nascent ...
Miriam Lee-Rueckert, Riikka Vikstedt, Jari Metso, Matti Jauhiainen, Petri T. Kovanen   +4 more
doaj   +1 more source

Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]

, 2014
Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce, Huang, Jincui, Lebrilla, Carlito B, Lee, Hyeyoung, Rivera, Nancy, Smilowitz, Jennifer T, Zivkovic, Angela M   +6 more
core   +1 more source

Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression [PDF]

Journal of Lipid Research, 2007
In addition to efficiently decreasing VLDL-triglycerides (TGs), fenofibrate increases HDL-cholesterol levels in humans. We investigated whether the fenofibrate-induced increase in HDL-cholesterol is dependent on the expression of the cholesteryl ester transfer protein (CETP).
Hoogt, C.C. van der, Haan, W. de, Westerterp, M., Hoekstra, M., Dallinga-Thie, G.M., Romijn, J.A., Princen, H.M.G., Jukema, J.W., Havekes, L.M., Rensen, P.C.N.   +9 more
openaire   +4 more sources

Insulin decreases plasma cholesteryl ester transfer but not cholesterol esterification in healthy subjects as well as in normotriglyceridaemic patients with type 2 diabetes [PDF]

, 1999
Background. Plasma cholesterol esterification (EST) and subsequent cholesteryl ester transfer (CET) from high-density lipoproteins (HDLs) towards apolipoprotein (apo) B-containing lipoproteins are key steps in HDL metabolism. Materials and methods.
Dullaart, R.P.F. (Robin), Riemens, S.C., Scheek, L. (Leo), Tol, A. (Arie) van   +3 more
core   +6 more sources

Decreased postprandial high density lipoprotein cholesterol and apolipoproteins A-I and E in normolipidemic smoking men: relations with lipid transfer proteins and LCAT activities

Journal of Lipid Research, 1998
We have previously reported that normolipidemic smokers are lipid intolerant due to increased responses of triglyceride-rich lipoproteins (TRL) apolipoprotein B-48, triglyceride (TG), and retinyl esters to a mixed meal compared to non-smokers.
N. Mero, A. Van Tol, L.M. Scheek, T. Van Gent, C. Labeur, M. Rosseneu, M-R. Taskinen   +6 more
doaj   +1 more source

Influence of different fat emulsions with 10 or 20% MCT/LCT or LCT on lipoproteins in plasma of patients after abdominal surgery [PDF]

, 1998
In patients after elective abdominal surgery, different fat emulsions were used to compare their efficacy in total parenteral nutrition and in normalizing plasma lipoprotein levels.
Hailer, Susanne, Jauch, Karl-Walter, Wolfram, Günther   +2 more
core   +1 more source

Cholesteryl Ester Transfer Protein Expressed in Lecithin Cholesterol Acyltransferase–Deficient Mice [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2002
Objective— Regulation of plasma cholesteryl ester transfer protein (CETP) concentration was studied in lecithin-cholesterol acyltransferase (LCAT)-knockout mice. Methods and Results— LCAT-knockout mice were cross-bred with CETP
Cheng-ai, Wu, Maki, Tsujita, Kuniko, Okumura-Noji, Shinichi, Usui, Hajime, Kakuuchi, Mitsuyo, Okazaki, Shinji, Yokoyama   +6 more
openaire   +2 more sources

Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism[S]

Journal of Lipid Research, 2010
Steroidogenic acute regulatory protein (StAR)D4 is a member of the StAR related lipid transfer family. Homology comes from the ∼210 amino acid lipid binding domain implicated in intracellular transport, cell signaling, and lipid metabolism.
Joshua J. Riegelhaupt, Marc P. Waase, Jeanne Garbarino, Daniel E. Cruz, Jan L. Breslow   +4 more
doaj   +1 more source

Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib. [PDF]

, 2018
BackgroundEarly detection of adverse effects of novel therapies and understanding of their mechanisms could improve the safety and efficiency of drug development.
DeLisle, Robert K, Ganz, Peter, Hyde, Craig, Malarstig, Anders, Murthy, Ashwin C, Ostroff, Rachel, Segal, Mark R, Weiss, Sophie J, Williams, Stephen A   +8 more
core   +2 more sources