Results 1 to 10 of about 12,113 (146)

Cholesteryl ester transfer protein and its inhibitors [PDF]

open access: yesJournal of Lipid Research, 2018
Most of the cholesterol in plasma is in an esterified form that is generated in potentially cardioprotective HDLs. Cholesteryl ester transfer protein (CETP) mediates bidirectional transfers of cholesteryl esters (CEs) and triglycerides (TGs) between ...
Sudichhya Shrestha   +4 more
doaj   +2 more sources

Purification and characterization of lipid transfer protein(s) from human lipoprotein-deficient plasma

open access: yesJournal of Lipid Research, 1982
Lipid transfer activities from human plasma have been characterized to determine whether triglyceride and cholesteryl ester transfer proteins are identical.
R E Morton, D B Zilversmit
doaj   +1 more source

Isolation and characterization of a phospholipid transfer protein (LTP-II) from human plasma.

open access: yesJournal of Lipid Research, 1988
In this report we have described the purification of a human plasma phospholipid transfer protein, designated LTP-II, which displayed the following characteristics: i) facilitated both the exchange and net mass transfer of lipoprotein phospholipids; ii ...
J H Tollefson, S Ravnik, J J Albers
doaj   +1 more source

Specificity of lipid transfer protein for molecular species of cholesteryl ester.

open access: yesJournal of Lipid Research, 1988
The capacity of the plasma-derived lipid transfer protein to facilitate the transfer of various cholesteryl ester species has been investigated. Four different molecular species of cholesteryl ester were incorporated into either reconstituted high ...
R E Morton
doaj   +1 more source

Interaction of plasma-derived lipid transfer protein with macrophages in culture

open access: yesJournal of Lipid Research, 1988
This study investigates the ability of human plasma-derived lipid transfer protein to facilitate lipid transfer to and from intact viable cells in culture.
R E Morton
doaj   +1 more source

High density lipoprotein subfractions isolated by heparin-Sepharose affinity chromatography and their role in cholesteryl ester transfer to very low density lipoproteins.

open access: yesJournal of Lipid Research, 1981
Normal human plasma HDL was applied to a column of heparin-Sepharose in the presence of MnCl(2) and three fractions were obtained by stepwise elution with increasing NaCl concentrations: a non-retained fraction (NR, 78% of protein) and two retained ...
Y L Marcel   +4 more
doaj   +1 more source

Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

open access: yesJournal of Lipid Research, 1985
The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry   +3 more
doaj   +1 more source

Apolipoprotein CI is a physiological regulator of cholesteryl ester transfer protein activity in human plasma but not in rabbit plasma

open access: yesJournal of Lipid Research, 2009
Plasma cholesteryl ester transfer protein (CETP) activity is high in rabbits, intermediate in humans, and nondetectable in rodents. Human apolipoprotein CI (apoCI) was found to be a potent inhibitor of CETP.
Jean-Paul Pais de Barros   +6 more
doaj   +1 more source

Use of fluorescent cholesteryl ester microemulsions in cholesteryl ester transfer protein assays

open access: yesJournal of Lipid Research, 1993
In the present report we describe a simple and practical method to assess CETP activity in a defined system by use of microemulsions containing a fluorescent cholesteryl ester analog.
CL Bisgaier   +4 more
doaj   +1 more source

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