Results 31 to 40 of about 7,033,015 (228)

Rat plasma lipoproteins: re-evaluation of a lipoprotein system in an animal devoid of cholesteryl ester transfer activity

Journal of Lipid Research, 1982
Plasma lipoproteins from male rats were isolated by rate zonal centrifugation. Four lipoproteins were identified: VLDL, LDL, HDL1, and HDL2. LDL, HLD1, and some HDL2 distributed within the salt density interval of 1.006-1.085 g/ml, while HDL2 was found ...
Y Oschry, S Eisenberg
doaj   +1 more source

In silico discovery of CETP inhibitors from ZINC15 compounds using docking, ADMET filtering, and molecular dynamics simulations

Research in Pharmaceutical Sciences
Background and purpose: Cholesteryl ester transfer protein is a crucial regulator of lipid metabolism and is considered a promising target for treating atherosclerotic cardiovascular disease. Given the clinical limitations and adverse effects of previous
Kimia Mohammadi, Mojgan Nejabat, Forough Mirabi, Amirhossein Sahebkar, Farzin Hadizadeh   +4 more
doaj   +1 more source

Characterization of cholesteryl ester transfer protein inhibitor from plasma of baboons (Papio sp.)

Journal of Lipid Research, 1993
Selective breeding has produced families of baboons that accumulate large high density lipoproteins (HDL1) when challenged with a high cholesterol and high fat (HCHF) diet.
RS Kushwaha, SQ Hasan, HC McGill, Jr, GS Getz, RG Dunham, P Kanda   +5 more
doaj   +1 more source

Total Synthesis and Stereochemical Assignment of the Quinquecyclopropane-Containing Cholesteryl Ester Transfer Protein Inhibitor U-106305

, 2016
Total Synthesis and Stereochemical Assignment of the Quinquecyclopropane-Containing Cholesteryl Ester Transfer Protein Inhibitor U ...
Anthony G. M. Barrett (1707928), David J. Williams (351580), Dieter Hamprecht (1720000), Andrew J. P. White (1310940)   +3 more
core   +1 more source

Effects of cholesteryl ester transfer protein TAQ1B polymorphism in renal transplant patients

, 2006
Background. Dyslipidemia is an important complication in renal transplant patients. Cholesteryl ester transfer protein (CETP) mediates the exchange of cholesteryl ester between high density lipoproteins and low density lipoproteins. The aim of this study
YILMAZ, Hülya, Zeybek, U, AKOGLU, E, Isbir, TURGAY, Ergen, Hayriye Arzu, HEKIM, N   +5 more
core   +1 more source

Inhibition of lipid transfer by a unique high density lipoprotein subclass containing an inhibitor protein.

Journal of Lipid Research, 1989
We have isolated from human plasma a unique subclass of the high density lipoproteins (HDL) which contains a potent lipid transfer inhibitor protein (LTIP) that inhibited cholesteryl ester, triglyceride, and phospholipid transfer mediated by the lipid ...
T Nishide, J H Tollefson, J J Albers
doaj   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Multiple-dose pharmacodynamics and pharmacokinetics of Anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects

, 2008
Cholesteryl ester transfer protein (CETP) is a plasma protein that catalyzes the heteroexchange of cholesteryl esters from high-density lipoprotein (HDL) and trglycerides to apolipoprotein B-containing lipoproteins, especially very low-density ...
Van Hoydonck, P, De Smet, M, Gendrano, I, Bloomfield, D, Cote, J, Van Dyck, K, Gottesdiener, K, Laethem, T, Bergman, A, Krishna, R, Laterza, O, Al-Huniti, N, Snyder, K, Van Bortel, Lucas, Chen, J, Chavez-Eng, C, Lutz, R, Guttierrez, M, Wagner, J, Dykstra, K, Fallon, M, Hilliard, D, Jin, B   +22 more
core   +1 more source

Epitope mapping for the anti-rabbit cholesteryl ester transfer protein monoclonal antibody that selectively inhibits triglyceride transfer

Journal of Lipid Research, 1999
Among the monoclonal antibodies (Mab) against rabbit plasma cholesteryl ester transfer protein (CETP), Mab 14-8F cross-reacted with human CETP and selectively inhibited triglyceride transfer but not cholesteryl ester transfer (Ko, K. W. S., T.
Kazunori Saito, Ki-ichiro Kobori, Hideyuki Hashimoto, Sachiko Ito, Mitsuhisa Manabe, Shinji Yokoyama   +5 more
doaj   +1 more source

Astrocyte‐Associated ABCA1/APOE Responses Accompany Hippocampal Lipid Remodeling and Ectopic Neuronal Accumulation During Epileptogenesis

Advanced Science, EarlyView.
During kainic acid‐induced epileptogenesis, astrocyte‐associated ATP‐binding cassette transporter A1 (ABCA1) and apolipoprotein E (APOE) responses accompany ectopic neurons and exploratory lipid alterations. In separate cohorts, bexarotene pretreatment and treatment on days 14–21 are associated with fewer ectopic hilar neurons and lower chronic seizure
Lu Chen, Xiao‐Rui Shi, Jia‐Yi Chen, Ying‐Ting Wang, Le Du, Yang Ni, Jun‐Min Chen, An‐Chen Guo, Qian Wu, Jian‐Ping Wu, Qun Wang   +10 more
wiley   +1 more source