Results 41 to 50 of about 7,033,015 (228)

Evidence for electronegativity of plasma high density lipoprotein-3 as one major determinant of human cholesteryl ester transfer protein activity.

Journal of Lipid Research, 1996
Plasma high density lipoprotein-3 (HDL3) subfractions with different composition and electric charge properties were isolated by anion exchange chromatography; their ability to exchange cholesteryl esters with low density lipoproteins (LDL) in the ...
D Masson, A Athias, L Lagrost
doaj   +1 more source

Are pregnancy‐ and lactation‐related eligibility criteria in cardiovascular clinical trials underpinned by drug safety data?

British Journal of Clinical Pharmacology, EarlyView.
Aim To quantify the prevalence of pregnancy‐, lactation‐ and reproductive potential‐related eligibility criteria in cardiovascular clinical trials and to evaluate whether they are supported by drug‐specific safety data. Methods We analysed randomized phase 3 and phase 4 cardiovascular clinical trials registered on ClinicalTrials.gov between 1 January ...
Jera Gurakuqi, Mira G. P. Zuidgeest, Susan van Dijk, Mariana Cajamarca Parra, Ewout W. Steyerberg, Ruurd J. A. Kuiper, Sanne A. E. Peters   +6 more
wiley   +1 more source

Reduced cholesteryl ester transfer in plasma of patients with lipoprotein lipase deficiency.

Journal of Lipid Research, 1996
The net mass transfer of cholesteryl ester (CE) from high density lipoprotein (HDL) to the apolipoprotein (apo) B-containing lipoproteins, very low density lipoprotein (VLDL) and low density lipoprotein (LDL) in plasma (cholesteryl ester transfer (CET ...
J D Bagdade, M C Ritter, H Lithell, D Bassett, F Mailly, P Talmud, M R Hayden   +6 more
doaj   +1 more source

Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy

Biotechnology Progress, EarlyView.
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung, Bin Dong, Jingqiao Shen, Yan Tan, Chi Zhang, Xiaoping Bao   +5 more
wiley   +1 more source

Isolation of Cholesteryl Ester Transfer Protein Inhibitors from Panax ginseng Roots.

, 1996
We have isolated cholesteryl ester transfer protein (CETP) inhibitors from the extract of Korean Panax ginseng C. A. MEYER roots and identified them as polyacetylene analogs.
Ji Youn Nam, Seung-Ho LEE, Song-Hae BOK, Seung Ho Lee, Tae Sook Jeong, Ji-Youn NAM, Young Kook Kim, Tae-Sook JEONG, Young-Kook KIM, Byoung-Mog KWON, Song Hae Bok   +10 more
core   +1 more source

Biochemical characterization of cholesteryl ester transfer protein inhibitors

Journal of Lipid Research, 2010
Cholesteryl ester transfer protein (CETP) has been identified as a novel target for increasing HDL cholesterol levels. In this report, we describe the biochemical characterization of anacetrapib, a potent inhibitor of CETP.
Mollie Ranalletta, Kathleen K. Bierilo, Ying Chen, Denise Milot, Qing Chen, Elaine Tung, Caroline Houde, Nadine H. Elowe, Margarita Garcia-Calvo, Gene Porter, Suzanne Eveland, Betsy Frantz-Wattley, Mike Kavana, George Addona, Peter Sinclair, Carl Sparrow, Edward A. O'Neill, Ken S. Koblan, Ayesha Sitlani, Brian Hubbard, Timothy S. Fisher   +20 more
doaj   +1 more source

Molecular Disorders of Cholesteryl Ester Transfer Protein

Journal of Atherosclerosis and Thrombosis, 1996
Plasma cholesteryl ester transfer protein (CETP) facilitates the transfer of cholesteryl ester (CE) from HDL to apolipoprotein B-containing lipoproteins and therefore is a key protein in the reverse cholesterol transport system. The importance of plasma CETP in lipoprotein metabolism has been highlighted by the discovery of CETP-deficient subjects with
Yamashita, Shizuya, Arai, Takeshi, Hirano, Ken-ichi, Sakai, Naohiko, Ishigami, Masato, Nakajima, Norimichi, Matsuzawa, Yuji   +6 more
openaire   +3 more sources

Annona squamosa: Phytochemical Fingerprinting, Health‐Improving Traits, and Functional Applications

Food Chemistry International, EarlyView.
Annona squamosa (custard apple) is a nutrient‐rich fruit containing diverse bioactive phytochemicals (e.g., acetogenins, flavonoids, and alkaloids) that contribute to multiple health benefits, including antioxidant, antihyperlipidemic, and antimicrobial activities, highlighting its potential as a functional food and medicinal resource.
Mohamed Fawzy Ramadan, Jumanah Reda Kurdi, Manar Yahya Alzahrani, Asmaa Ibrahim Alshaikhi, Jumanah Samir Hazzazi   +4 more
wiley   +1 more source

Effect of growth hormone replacement therapy on plasma lecithin:cholesterol acyltransferase and lipid transfer protein activities in growth hormone-deficient adults

Journal of Lipid Research, 2000
The effects of growth hormone (GH) replacement on plasma lecithin:cholesterol acyltransferase (LCAT), cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP), factors involved in high density lipoprotein (HDL) metabolism, are ...
John A.M. Beentjes, Arie van Tol, Wim J. Sluiter, Robin P.F. Dullaart   +3 more
doaj   +1 more source

Lipid‐inclusive metabolomics of infants born after suspected preterm labor according to whether delivery occurred preterm or at term: A prospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize the cord blood metabolic profile of infants born after suspected preterm labor (sPTL) according to whether delivery occurred preterm or at term compared with infants from uncomplicated pregnancies. Study Design Prospective observational cohort study including singleton pregnancies complicated by sPTL and uncomplicated
Lina Youssef, Natalia Abadía‐Cuchí, Juan Lerma‐Irureta, Jesús Orduna, María Savirón, Irene Orera, Ana Medel‐Martinez, Marta Fabre, Jesús González, Pilar Maestro‐Quibus, Sara Ruiz‐Martinez, Jon Schoorlemmer, Diego Lerma, Daniel Oros, Cristina Paules   +14 more
wiley   +1 more source