Results 1 to 10 of about 1,222,571 (255)

Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols. [PDF]

open access: yesNat Commun, 2023
Cellular cholesterol can be metabolized to its fatty acid esters, cholesteryl esters (CEs), to be stored in lipid droplets (LDs). With triacylglycerols (TGs), CEs represent the main neutral lipids in LDs. However, while TG melts at ~4 °C, CE melts at ~44 
Dumesnil C   +10 more
europepmc   +2 more sources

Free cholesterol and cholesterol esters in bovine oocytes: Implications in survival and membrane raft organization after cryopreservation. [PDF]

open access: yesPLoS One, 2017
Part of the damage caused by cryopreservation of mammalian oocytes occurs at the plasma membrane. The addition of cholesterol to cell membranes as a strategy to make it more tolerant to cryopreservation has been little addressed in oocytes.
Buschiazzo J   +4 more
europepmc   +2 more sources

Exploring antimicrobial properties of cholesterol esters: a systematic literature review

open access: yesAll Life, 2022
Antibiotic resistance has become an increasingly common problem in treating infectious diseases caused by pathogenic micro-organisms, and this threat is heightened due to the lack of new antibiotic discoveries since the 1980s.
Timothy Jong, Poonam Mudgil
doaj   +1 more source

Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

open access: yesSignal Transduction and Targeted Therapy, 2022
Disturbed cholesterol homeostasis plays critical roles in the development of multiple diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and cancers, particularly the CVD in which the accumulation of lipids (mainly the ...
Yajun Duan   +5 more
semanticscholar   +1 more source

Cholesterol and Cholesterol Esters in Mycoplasma [PDF]

open access: yesJournal of General Microbiology, 1965
Free and esterified cholesterol were determined in the lipid extract of nine parasitic and saprophytic Mycoplasma strains. The saprophytic strains were usally free from esterified cholesterol. Esterified cholesterol was found in the parasitic strains at a ratio of 1:8 to 1:3 to free cholesterol; in the growth medium the ratio was about 4:1 [4-14C ...
M, ARGAMAN, S, RAZIN
openaire   +2 more sources

Cholesterol ester droplets and steroidogenesis [PDF]

open access: yesMolecular and Cellular Endocrinology, 2013
Intracellular lipid droplets (LDs) are dynamic organelles that contain a number of associated proteins including perilipin (Plin) and vimentin. Cholesteryl ester (CE)-rich LDs normally accumulate in steroidogenic cells and their mobilization is the preferred initial source of cholesterol for steroidogenesis.
Fredric B, Kraemer   +3 more
openaire   +2 more sources

Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans. [PDF]

open access: yesPLoS ONE, 2014
The inflammatory component of non-alcoholic steatohepatitis (NASH) can lead to irreversible liver damage. Therefore there is an urgent need to identify novel interventions to combat hepatic inflammation.
Jogchum Plat   +15 more
doaj   +1 more source

Thermal transitions and structural properties of synthetic cholesterol alkyl and alkenyl ethers: analogues of biological cholesterol esters.

open access: yesJournal of Lipid Research, 1983
Nine even-numbered saturated (C4 to C20) and two unsaturated (C18:1, C18:2) cholesterol alkyl ethers were studied by differential scanning calorimetry, polarizing microscopy, and X-ray powder diffraction.
R J Deckelbaum, G Halperin, D Atkinson
doaj   +1 more source

Polyphenol alkyl ester inhibits membrane cholesterol domain formation through an antioxidant mechanism based, in nonlinear fashion, on chain length [PDF]

open access: yes, 2017
Under conditions of oxidative stress, cholesterol aggregates into discrete membrane bilayer domains that precipitate the formation of extracellular crystals, a hallmark feature of the advanced atheroma in cardiovascular disease.
Durand, Erwann   +4 more
core   +1 more source

Effect of very low-density lipoproteins on lipid transfer in incubated serum

open access: yesJournal of Lipid Research, 1965
Incubation of human serum solutions low in glyceride content for 16 hr resulted in a net increase of cholesterol esters in all three major human serum lipoprotein classes, namely the very low-density lipoproteins of d < 1.006 (VLDL), low-density ...
A.V. Nichols, L. Smith
doaj   +1 more source

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