Modulation of plasma lipid levels and cholesterol kinetics by phytosterol versus phytostanol esters
It has been suggested that phytosterol and phytostanol esters possess similar cholesterol-lowering properties, however, whether mechanisms responsible are identical has not been addressed.
Peter J. Jones +5 more
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Absorption of cholesterol during inhibition of mucosal acyl CoA:cholesterol acyltransferase was studied in mesenteric lymph fistula rats with normal pancreatic function.
S B Clark, A M Tercyak
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A method for rapid microsynthesis of radioactive cholesterol esters
A simple method for synthesizing esters of labeled cholesterol of high specific activity is described. The formation of acyl chlorides takes 10 min and they are reacted with labeled cholesterol to form the cholesterol esters in another 5 min. Yields were
Karoly G. Pinter +2 more
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Apolipoprotein E4 is deficient in inducing macrophage ABCA1 expression and stimulating the Sp1 signaling pathway. [PDF]
ATP binding cassette A1 (ABCA1) is a membrane protein that promotes cellular cholesterol efflux. Using RAW 264.7 macrophages, we studied the relative effects of apolipoprotein (apo) E3 and apoE4 on ABCA1 and on the signaling pathway that regulates its ...
Emmanuel Ugochukwu Okoro +5 more
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Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]
Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Paumgartner, Gustav +4 more
core +1 more source
Incorporation of labeled cholesterol esters into chylomicrons in vitro
Labeled cholesterol esters were incorporated into chylomicrons in vitro by adding an acetone solution of the cholesterol ester to a suspension of washed chylomicrons. The physical and metabolic properties of the added labeled ester were the same as those
Steven H. Quarfordt, DeWitt S. Goodman
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Urinary cholesterol in cancer screening [PDF]
Cholesterol determinations in morning urine samples were taken in 235 selected patients with a positive test for microscopic hematuria. Values ranged from 0.2 to 76.0 mg (median 5.5) in 23 patients with urologic malignancies and from 0.1 to 33.4 mg ...
Tauber, Roland +3 more
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Comparison of Cholesterol Lowering Diets: Apple, Casein Cytochrom P450 protein and Cholesterol 7α Hydroxylase Activities in Hamsters [PDF]
Lithogenic diet, casein and apple fiber diets were fed to hamsters for 3-5 weeks. For control group, animals were fed on normal Purina chow without any supplement.
Rakesh Sharma +3 more
core +1 more source
Early steps in steroidogenesis: intracellular cholesterol trafficking
Steroid hormones are made from cholesterol, primarily derived from lipoproteins that enter cells via receptor-mediated endocytosis. In endo-lysosomes, cholesterol is released from cholesterol esters by lysosomal acid lipase (LAL; disordered in Wolman ...
Walter L. Miller, Himangshu S. Bose
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Cholesterol esters of long-chain saturated fatty acids (C12 to C22), as well as those of the C18 unsaturated fatty acids (oleic, linoleic, and linolenic), were prepared by the ester interchange method, starting with cholesteryl acetate and the methyl ...
V. Mahadevan, W.O. Lundberg
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