Results 21 to 30 of about 46,376 (166)

Early steps in steroidogenesis: intracellular cholesterol trafficking

open access: yesJournal of Lipid Research, 2011
Steroid hormones are made from cholesterol, primarily derived from lipoproteins that enter cells via receptor-mediated endocytosis. In endo-lysosomes, cholesterol is released from cholesterol esters by lysosomal acid lipase (LAL; disordered in Wolman ...
Walter L. Miller, Himangshu S. Bose
doaj   +1 more source

Preparation of cholesterol esters of long-chain fatty acids and characterization of cholesteryl arachidonate*

open access: yesJournal of Lipid Research, 1962
Cholesterol esters of long-chain saturated fatty acids (C12 to C22), as well as those of the C18 unsaturated fatty acids (oleic, linoleic, and linolenic), were prepared by the ester interchange method, starting with cholesteryl acetate and the methyl ...
V. Mahadevan, W.O. Lundberg
doaj   +1 more source

Serum cholesterol, cholesterol precursors, and plant sterols in hypercholesterolemic subjects with different apoE phenotypes during dietary sitostanol ester treatment

open access: yesJournal of Lipid Research, 1993
A randomized double-blind study was made in 67 modestly hypercholesterolemic subjects by replacing 50 g of daily dietary fat by the same amount of a rapeseed oil preparation without and with fat-soluble sitostanol esters.
HT Vanhanen   +6 more
doaj   +1 more source

The influence of exogenous cholesterol on hepatic lipid composition of the rat*

open access: yesJournal of Lipid Research, 1962
Rats were fed diets containing cottonseed oil and/or cholesterol, cholic acid, methyl esters of long-chain fatty acids, and tocopherol. Livers, hearts, and aortas were examined histologically; liver lipids were fractionated by silicic acid chromatography;
Robert J. Morin   +3 more
doaj   +1 more source

Factice chromatography: An automatically monitored, liquid-gel system for the separation of nonpolar lipids*

open access: yesJournal of Lipid Research, 1963
A technique of column chromatography using factice, a hydrophobic polymer, as stationary phase, and aqueous acetone as moving phase is described.
Jules Hirsch
doaj   +1 more source

In vitro incorporation of cholesterol-14C in to very low density lipoprotein cholesteryl esters

open access: yesJournal of Lipid Research, 1968
The cholesteryl esters of very low density lipoproteins become labeled when human plasma is incubated with cholesterol-14C. The relative order of magnitude of the specific activity of the cholesteryl esters of the major lipoprotein fractions is: high ...
Yasuo Akanuma, John Glomset
doaj   +1 more source

Mechanism of the defect in cholesteryl ester clearance from macrophages of atherosclerosis-susceptible White Carneau pigeons.

open access: yesJournal of Lipid Research, 1994
Recent studies from our laboratory (Yancey, P.G., and R. W. St. Clair. 1992. Arterioscler. Thromb. 12: 1291-1304) have shown that cultured peritoneal macrophages from White Carneau (WC) pigeons clear cholesteryl esters at a slower rate than do ...
P G Yancey, R W St Clair
doaj   +1 more source

The formation and consequences of cholesterol-rich deposits in atherosclerotic lesions

open access: yesFrontiers in Cardiovascular Medicine, 2023
Cardiovascular diseases remain the leading cause of death throughout the world. Accumulation of lipoprotein-associated lipids and their interaction with macrophages are early steps in the development of atherosclerotic lesions.
Frederick R. Maxfield   +2 more
doaj   +1 more source

Effect of large doses of the oral contraceptive Enovid on cholesterol metabolism in the rat

open access: yesJournal of Lipid Research, 1968
Short-term effects of the oral contraceptive drug, Enovid, a mixture of estrogenic and progesterone compounds, have been determined in experiments on male and female rats.
Lilla Aftergood   +2 more
doaj   +1 more source

Purification of neutral lipid fractions by thin-layer chromatography on aluminum oxide

open access: yesJournal of Lipid Research, 1965
Two-stage thin-layer chromatography on Aluminum Oxide G has been used to separate triglycerides, cholesterol, cholesterol esters, and diglycerides from contaminating fatty acids present in the lipid mixtures.
J.M. Lederkremer, Ralph M. Johnson
doaj   +1 more source

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