Results 101 to 110 of about 440,457 (288)

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

open access: yesAdvanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li   +23 more
wiley   +1 more source

Turnover of Individual Cholesterol Esters in Human Liver and Plasma*

open access: yes, 1966
There are several lines of evidence which sug-gest that the liver is a major source of plasma cho-lesterol esters. First, eviscerated rats cannot main-tain a normal concentration of cholesterol esters in the plasma (1); second, when isotopically la-beled
E. A. Couzens, P. J. Nestel T
core  

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

open access: yesAdvanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu   +7 more
wiley   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Increased levels of cholesterol esters in glioma tissue and surrounding areas of human brain

open access: yes, 1997
The proliferation of glioma cells requires cholesterol, which could be provided by synthesis within the cells or by uptake of cholesterol esters in particles of Low Density Lipoprotein (LDL).
von, Holst H   +3 more
core   +1 more source

Series of Concentration-Induced Phase Transitions in Cholesterol/Phosphatidylcholine Mixtures [PDF]

open access: yes, 2013
In lipid membranes, temperature-induced transition from gel-to-fluid phase increases the lateral diffusion of the lipid molecules by three orders of magnitude.
István P. Sugár   +6 more
core   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

open access: yesAdvanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton   +13 more
wiley   +1 more source

The determination of esterified fatty acids in glycerides, cholesterol esters, and phosphatides

open access: yesJournal of Lipid Research, 1962
The conditions for the hydroxamic acid reaction for determining esterified fatty acids have been modified to control the variable factors involved and to obtain molar absorptivities per ester group for triglycerides, cholesterol esters of long-chain ...
Wesley D. Skidmore, C. Entenman
doaj   +1 more source

Non-linear optical imaging of atherosclerotic plaques in the context of SIV and HIV infection prominently detects crystalline cholesterol esters. [PDF]

open access: yesPLoS One, 2021
Park MH   +13 more
europepmc   +1 more source

POTENTIAL HEALTHCARE SAVINGS FROM PLANT STEROL ENRICHED FOODS IN CANADA [PDF]

open access: yes
Increased consumption of foods containing plant sterols has the potential to reduce the incidence of coronary heart disease (CHD) and thus reduce costs associated with treating that disease in a significant way.
Gyles, Collin   +2 more
core  

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