Results 81 to 90 of about 440,457 (288)

The C18 fatty acids of ox plasma lipids

Journal of Lipid Research, 1962
The fatty acid composition of the cholesterol esters, triglycerides, phospholipids, and free fatty acids from the pooled plasma of four grass-fed, maiden heifers was determined by gas-liquid chromatography.
W.R.H. Duncan, G.A. Garton
doaj   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]

, 1994
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Ritter, Christoph von, Lange, Volker, Del Pozo, Reginals, Paumgartner, Gustav, V. Lange, J. F. Miquel, R. Del Pozo, G. Paumgartner, Jüngst, Dieter, Miquel, Juan Francisco, C. Von Ritter, D. Jungst   +11 more
core   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Detectability of testosterone esters and estradiol benzoate in bovine hair and plasma following pour-on treatment [PDF]

, 2009
The abuse of synthetic esters of natural steroids such as testosterone and estradiol in cattle fattening and sports is hard to detect via routine urine testing. The esters are rapidly hydrolysed in vivo into substances which are also endogenously present
Blokland, M.H., Becker, C., C. Becker, Nielen, M.W.F., Lasaroms, J.J.P., I. Riedmaier, H. H. D. Meyer, Riedmaier, I., A. W. J. M. Nijrolder, Stolker, A.A.M., Meyer, H.H.D., M. J. Groot, J. J. P. Lasaroms, M. H. Blokland, Groot, M.J., Nijrolder, A.W.J.M., M. W. F. Nielen, A. A. M. Stolker   +17 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Total cholesterol, cholesteryl esters and free cholesterol.

, 2015
Plasma concentration of total cholesterol (Fig 1a), cholesteryl esters (Fig 1b) and free cholesterol (Fig 1c) in week 1 p.p., and before (week 0) and after (week 3) feed restriction in mid-lactation.
Evelyne C. Kessler (748451), Christiane Albrecht (212014), Rupert M. Bruckmaier (517452), Josef J. Gross (748450)   +3 more
core   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

The effect of oligomeric procyanidins on endothelial function and cholesterol homeostasis [PDF]

, 2012
PhDOligomeric procyanidins (OPC) are naturally occurring dietary substances, which studies suggest can protect against cardiovascular disease. To explore this further a double-blind randomised controlled crossover trial, EPICURE (Evaluation of high ...
Rull, Gurvinder Kaur
core   +3 more sources

Investigating the Effects of Statins on Cellular Lipid Metabolism Using a Yeast Expression System [PDF]

, 2009
In humans, defects in lipid metabolism are associated with a number of severe diseases such as atherosclerosis, obesity and type II diabetes. Hypercholesterolemia is a primary risk factor for coronary artery disease, the major cause of premature deaths
Zimnicka, Magdalena, Szkopinska, Anna, Burzynska, Beata, Kania, Magdalena, Wysocka-Kapcinska, Monika, Kiliszek, Marek, Danikiewicz, Witold, Plochocka, Danuta, Leszczynska, Agata, Kaminska, Joanna   +9 more
core   +3 more sources