Abnormal cholesterol–cholesteryl ester metabolism impairs mouse oocyte quality during ovarian aging [PDF]
Background Ovarian aging-induced decline in oocyte quality has been a main issue in women of advanced maternal age. However, the potential mechanism remains elusive, and there are no effective strategies to ameliorate aged oocyte quality.
Sainan Zhang +12 more
doaj +2 more sources
The surface behavior of a series of cholesteryl esters was studied in mixtures with a model phospholipid, 1-palmitoyl-2-oleoyl phosphatidylcholine. The cholesteryl esters were representative of the predominant forms occurring naturally and qualitative ...
J M Smaby, H L Brockman
doaj +3 more sources
Plasma cholesteryl ester fatty acids do not mediate the association of ethnicity with type 2 diabetes: results from the HELIUS study [PDF]
Scope: Ethnic minority groups have a higher risk of type 2 diabetes (T2D) than the host population. Our aim was to identify whether plasma cholesteryl ester fatty acids (CEFA) mediate the ethnic differences in type 2 diabetes. Methods and results:
Celis-Morales, Carlos +5 more
core +12 more sources
Cholesteryl Ester Transfer Protein Penetrates Lipoproteins For Cholesteryl Ester Transfer [PDF]
Human cholesteryl ester transfer protein (CETP), a hydrophobic glycoprotein (476 amino acids, ∼74 kDa), mediates the transfer of cholesteryl ester (CE) from high-density lipoproteins (HDL) to apo-B containing lipoproteins (low-density lipoproteins - LDL; very low density lipoproteins - VLDL).
Ren, Gang +8 more
openaire +1 more source
Oxidized cholesteryl esters and inflammation [PDF]
The oxidation hypothesis of atherosclerosis proposes that oxidized LDL is a major causative factor in the development of atherosclerosis. Although this hypothesis has received strong mechanistic support and many animal studies demonstrated profound atheroprotective effects of antioxidants, which reduce LDL oxidation, the results of human clinical ...
Choi, Soo-Ho +2 more
openaire +4 more sources
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
core +2 more sources
The concentration dependence and tissue distribution of high density lipoprotein (HDL) cholesteryl ester and apolipoprotein (apo) transport were determined in apoA-I knockout mice (apoA-I-/-) that lack normal HDL in plasma. Rates of HDL cholesteryl ester
David K. Spady +3 more
doaj +1 more source
Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster [PDF]
BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to ...
Contos, Linda M +4 more
core +2 more sources
Analysis of adrenal cholesteryl esters by reversed phase high performance liquid chromatography.
A reversed phase high performance liquid chromatographic (HPLC) method was developed for direct profiling and determination of adrenal cholesteryl ester composition.
B Cheng, J Kowal
doaj +1 more source
Inhibitors of neutral cholesteryl ester hydrolase.
p-Nitrophenyl N-butyl, N-octyl, and N-dodecyl carbamates and a newly synthesized diethyl phosphate compound were studied as potential inhibitors of the cholesteryl ester hydrolases of Fu5AH rat hepatoma cells.
EH Harrison +5 more
doaj +1 more source

