Results 51 to 60 of about 1,698,727 (261)
Triglyceride and cholesteryl ester hydrolysis in a cell culture model of smooth muscle foam cells.
Cultured rabbit aortic smooth muscle cells were converted to foam cells by exposure to sonicated lipid droplets of defined composition using an inverted culture technique. Uptake of the lipid droplets by the cells was shown to be dependent on the time of
L K Minor, G H Rothblat, J M Glick
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Cholesteryl ester hydrolysis in J774 macrophages occurs in the cytoplasm and lysosomes
The relationship of cholesteryl ester hydrolysis to the physical state of the cholesteryl ester in J774 murine macrophages was explored in cells induced to store cholesteryl esters either in anisotropic (ordered) inclusions or isotropic (liquid ...
Stewart J. Avart +3 more
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Isolation and characterization of a phospholipid transfer protein (LTP-II) from human plasma.
In this report we have described the purification of a human plasma phospholipid transfer protein, designated LTP-II, which displayed the following characteristics: i) facilitated both the exchange and net mass transfer of lipoprotein phospholipids; ii ...
J H Tollefson, S Ravnik, J J Albers
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Metabolic labelling of cholesteryl glucosides in Helicobacter pylori reveals how the uptake of human lipids enhances bacterial virulence. [PDF]
Helicobacter pylori infects approximately half of the human population and is the main cause of various gastric diseases. This pathogen is auxotrophic for cholesterol, which it converts upon uptake to various cholesteryl α-glucoside derivatives ...
Chen, Yet-Ran +11 more
core +1 more source
Prevalence of Cholesteryl Ester Storage Disease [PDF]
Cholesteryl ester storage disease (CESD) is an autosomal recessive chronic liver disease caused by lysosomal acid lipase (LAL) deficiency. The gene is located on chromosome 10q23.2-q23.3, and the enzyme is essential for triglycerides and cholesteryl ester hydrolysis in lysosomes.
MUNTONI, SANDRO +8 more
openaire +3 more sources
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin +4 more
wiley +1 more source
We have previously shown that very low density lipoproteins (VLDL, Sf 60–400) from subjects with type IV hyperlipoproteinemia (HTG-VLDL) will induce appreciable cholesteryl ester accumulation in cultured macrophages (J774A.1).
Stewart C. Whitman +4 more
doaj +1 more source
Macrophage cholesteryl ester mobilization and atherosclerosis [PDF]
Accumulation of cholesteryl esters (CE) stored as cytoplasmic lipid droplets is the main characteristic of macrophage foam cells that are central to the development of atherosclerotic plaques. Since only unesterified or free cholesterol (FC) can be effluxed from the cells to extracellular cholesterol acceptors, hydrolysis of CE is the obligatory first ...
Shobha, Ghosh +3 more
openaire +2 more sources
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
Environmental effects of natural dyes and syntetic dyes: a comparison [PDF]
Dyes is important to add colorant on fabrics. The dyeing process makes a fabric colourful and attractive. However, the waste disposed by dyeing process was hazard to environment especially synthetic dyes.
Jalil, Anis Jazira +3 more
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