Results 1 to 10 of about 22,982 (206)

Cholesteryl ester transfer protein and its inhibitors [PDF]

Journal of Lipid Research, 2018
Most of the cholesterol in plasma is in an esterified form that is generated in potentially cardioprotective HDLs. Cholesteryl ester transfer protein (CETP) mediates bidirectional transfers of cholesteryl esters (CEs) and triglycerides (TGs) between ...
Sudichhya Shrestha, Ben J. Wu, Liam Guiney, Philip J. Barter, Kerry-Anne Rye   +4 more
doaj   +5 more sources

Use of fluorescent cholesteryl ester microemulsions in cholesteryl ester transfer protein assays

Journal of Lipid Research, 1993
In the present report we describe a simple and practical method to assess CETP activity in a defined system by use of microemulsions containing a fluorescent cholesteryl ester analog.
CL Bisgaier, LL Minton, AD Essenburg, A White, R Homan   +4 more
doaj   +3 more sources

Cholesteryl ester transfer protein and hyperalphalipoproteinemia in Caucasianss⃞ [PDF]

Journal of Lipid Research, 2007
It is unclear whether cholesteryl ester transfer protein (CETP) contributes to high density lipoprotein cholesterol (HDL-C) levels in hyperalphalipoproteinemia (HALP) in Caucasians.
Wim A. van der Steeg, G. Kees Hovingh, Anke H.E.M. Klerkx, Barbara A. Hutten, Inge C. Nootenboom, Johannes H.M. Levels, Arie van Tol, Gees M. Dallinga-Thie, Aeilko H. Zwinderman, John J.P. Kastelein, Jan Albert Kuivenhoven   +10 more
doaj   +3 more sources

Biochemical characterization of cholesteryl ester transfer protein inhibitors [PDF]

Journal of Lipid Research, 2010
Cholesteryl ester transfer protein (CETP) has been identified as a novel target for increasing HDL cholesterol levels. In this report, we describe the biochemical characterization of anacetrapib, a potent inhibitor of CETP.
Mollie Ranalletta, Kathleen K. Bierilo, Ying Chen, Denise Milot, Qing Chen, Elaine Tung, Caroline Houde, Nadine H. Elowe, Margarita Garcia-Calvo, Gene Porter, Suzanne Eveland, Betsy Frantz-Wattley, Mike Kavana, George Addona, Peter Sinclair, Carl Sparrow, Edward A. O'Neill, Ken S. Koblan, Ayesha Sitlani, Brian Hubbard, Timothy S. Fisher   +20 more
doaj   +3 more sources

Plasma cholesteryl ester transfer protein

Journal of Lipid Research, 1993
AR Tall
doaj   +3 more sources

Insulin decreases plasma cholesteryl ester transfer but not cholesterol esterification in healthy subjects as well as in normotriglyceridaemic patients with type 2 diabetes [PDF]

, 1999
Background. Plasma cholesterol esterification (EST) and subsequent cholesteryl ester transfer (CET) from high-density lipoproteins (HDLs) towards apolipoprotein (apo) B-containing lipoproteins are key steps in HDL metabolism. Materials and methods.
Dullaart, R.P.F. (Robin), Riemens, S.C., Scheek, L. (Leo), Tol, A. (Arie) van   +3 more
core   +12 more sources

Cholesteryl Ester Transfer Protein Penetrates Lipoproteins For Cholesteryl Ester Transfer [PDF]

Biophysical Journal, 2010
Human cholesteryl ester transfer protein (CETP), a hydrophobic glycoprotein (476 amino acids, ∼74 kDa), mediates the transfer of cholesteryl ester (CE) from high-density lipoproteins (HDL) to apo-B containing lipoproteins (low-density lipoproteins - LDL; very low density lipoproteins - VLDL).
Ren, Gang, Zhang, Shengli, Cavigiolio, Giorgio, Lei, Dongsheng, Oda, Michael, Weisgraber, Karl H., Rye, Kerry-Anne, Pownall, Henry J., Qiu, Xiayang   +8 more
openaire   +1 more source

Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]

, 2020
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui, Huang, Jiansheng, Huang, Li-Hao, Wang, Dongdong   +3 more
core   +2 more sources

Cholesteryl Ester Transfer Protein Inhibition [PDF]

Journal of the American College of Cardiology, 2006
Chemicals / CAS: 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester, 211513-37-0; atorvastatin, 134523-00-5, 134523-03-8; nicotinic acid, 54-86-4, 59-67-6; torcetrapib, 262352-17-0; Carrier Proteins; CETP protein, human; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Glycoproteins ...
Milani, Richard V., Lavie, Carl J.
openaire   +3 more sources

Purification and characterization of lipid transfer protein(s) from human lipoprotein-deficient plasma

Journal of Lipid Research, 1982
Lipid transfer activities from human plasma have been characterized to determine whether triglyceride and cholesteryl ester transfer proteins are identical.
R E Morton, D B Zilversmit
doaj   +1 more source