Results 31 to 40 of about 32,808 (269)

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport [PDF]

, 2014
A potent class of indolinyl-thiazole based inhibitors of cellular lipid uptake mediated by scavenger receptor, class B, type I (SR-BI) was identified via a high-throughput screen of the National Institutes of Health Molecular Libraries Small Molecule ...
Bennion, Melissa, Dandapani, Sivaraman, Dockendorff, Chris, Faloon, Patrick W., Krieger, Monty, Lam, Garrett, Lewis, Timothy A., Munoz, Benito, Nag, Partha P., Negri, Joseph, Nieland, Thomas J.F., Palmer, Michelle A., Paterson, Conor, Penman, Marsha, Perez, José R., Pu, Jun, Schreiber, Stuart L., Youngsaye, Willmen, Yu, Miao   +18 more
core   +3 more sources

Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

Journal of Lipid Research, 1985
The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry, T Olivecrona, R J Deckelbaum, S Eisenberg   +3 more
doaj   +1 more source

The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans [PDF]

, 1997
Cafestol and kahweol–diterpenes present in unfiltered coffee— strongly raise serum VLDL and LDL cholesterol and slightly reduce HDL cholesterol in humans. The mechanism of action is unknown.
Gent, T. van, Jong-Caesar, R. de, Katan, M.B., Roos, B. de, Scheek, L. M., Tol, A. van, Urgert, R.   +6 more
core   +3 more sources

Apolipoprotein CI is a physiological regulator of cholesteryl ester transfer protein activity in human plasma but not in rabbit plasma

Journal of Lipid Research, 2009
Plasma cholesteryl ester transfer protein (CETP) activity is high in rabbits, intermediate in humans, and nondetectable in rodents. Human apolipoprotein CI (apoCI) was found to be a potent inhibitor of CETP.
Jean-Paul Pais de Barros, Aurélia Boualam, Thomas Gautier, Laure Dumont, Bruno Vergès, David Masson, Laurent Lagrost   +6 more
doaj   +1 more source

Accelerated cholesteryl ester transfer and altered lipoprotein composition in diabetic cynomolgus monkeys.

Journal of Lipid Research, 1995
To determine whether nonhuman primates demonstrate the same alterations in transport of cholesteryl ester (CE) in plasma observed in diabetic humans, cholesteryl ester transfer (CET) was measured in cynomolgus monkeys with chronic spontaneous diabetes ...
J D Bagdade, J D Wagner, L L Rudel, T B Clarkson   +3 more
doaj   +1 more source

Cholesteryl ester-rich microemulsions: stable protein-free analogs of low density lipoproteins.

Journal of Lipid Research, 1982
A method has been devised for the preparation of stable lipid microemulsions containing cholesterol, cholesteryl ester, phosphatidylcholine, and trioleoylglycerol in the relative molar ratios found in low density lipoproteins.
D P Via, I F Craig, G W Jacobs, W B Van Winkle, S C Charlton, A M Gotto, Jr, L C Smith   +6 more
doaj   +1 more source

Deficiency of Cholesteryl Ester Transfer Protein Protects Against Atherosclerosis in Rabbits. [PDF]

Arterioscler Thromb Vasc Biol, 2017
Zhang J, Niimi M, Yang D, Liang J, Xu J, Kimura T, Mathew AV, Guo Y, Fan Y, Zhu T, Song J, Ackermann R, Koike Y, Schwendeman A, Lai L, Pennathur S, Garcia-Barrio M, Fan J, Chen YE.   +18 more
europepmc   +2 more sources

Apolipoprotein E enhances lipid exchange between lipoproteins mediated by cholesteryl ester transfer protein.

Journal of Lipid Research, 1993
The direct effect of apolipoprotein (apo) E on cholesteryl ester transfer protein (CETP) activity was studied using lipoproteins from a subject with apoE deficiency (Atherosclerosis. 1991. 88: 15-20) as a model system.
M Kinoshita, H Arai, M Fukasawa, T Watanabe, K Tsukamoto, Y Hashimoto, K Inoue, K Kurokawa, T Teramoto   +8 more
doaj   +1 more source

Cholesteryl ester transfer from phospholipid vesicles to human density lipoproteins.

Journal of Lipid Research, 1981
The exchange of cholesteryl esters between different lipoproteins was reported to bae mediated by a protein present in human plasma. In this study wer have examined the movement of cholesteryl ester from unilamellar phospholipid vesicles to high density ...
P M Young, P Brecher
doaj   +1 more source

Elevation of plasma phospholipid transfer protein increases the risk of atherosclerosis despite lower apolipoprotein B-containing lipoproteins. [PDF]

, 2004
Plasma phospholipid transfer protein (PLTP) transfers phospholipids between lipoproteins and mediates HDL conversion. PLTP-overexpressing mice have increased atherosclerosis.
Arai, Arie van Tol, Barter, Barter, Bruce, De Geest, Delsing, Ehnholm, Farah Sadeghi-Niaraki, Fielding, Forte, Föger, Herrera, Huuskonen, Jauhiainen, Jessica Lie, Jiang, Jiang, Jiang, Kawano, Leo Scheek, Libby, Lie, Lie, Mackness, Marotti, Mason, Okamoto, Plump, Qin, Quarck, Redgrave, Rien van Haperen, Rini de Crom, Rodrigo, Rye, Shih, Speijer, Tall, Teus van Gent, Tselepis, Tu, Tward, Van Haperen, Van Tol, Van Tol, Watson, Wolfbauer   +47 more
core   +3 more sources