Results 41 to 50 of about 32,808 (269)

CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects

Arteriosclerosis, Thrombosis and Vascular Biology, 2017
Objective— Lp(a) [lipoprotein (a)] is composed of apoB (apolipoprotein B) and apo(a) [apolipoprotein (a)] and is an independent risk factor for cardiovascular disease and aortic stenosis.
T. Thomas, Haihong Zhou, W. Karmally, R. Ramakrishnan, S. Holleran, Yang Liu, Patricia A. Jumes, J. Wagner, B. Hubbard, S. Previs, Thomas A. Roddy, A. Johnson-Levonas, D. Gutstein, S. Marcovina, D. Rader, H. Ginsberg, J. Millar, G. Reyes-Soffer   +17 more
semanticscholar   +1 more source

Comparative study of phospholipid transfer activities mediated by cholesteryl ester transfer protein and phospholipid transfer protein.

Journal of Lipid Research, 1994
In the present study, a sequential procedure was set up to separate simultaneously cholesteryl ester transfer protein (CETP), phospholipid transfer protein (PTP), and lecithin:cholesterol acyltransferase (LCAT) from human plasma.
L Lagrost, A Athias, P Gambert, C Lallemant   +3 more
doaj   +1 more source

Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype [PDF]

, 2014
The aim of the present study was to establish mitochondrial cholesterol trafficking 18 kDa translocator protein (TSPO) as a potential therapeutic target, capable of increasing macrophage cholesterol efflux to (apo)lipoprotein acceptors.
Anne-Marie Allen, Annette Graham, Batarseh, Bird, Borthwick, Borthwick, Brown, Dmitrova-Shumkovska, Engel, Falchi, Farke, Feramisco, Fernandez-Hernando, Gallus, Gerrity, Gut, Hebbachi, Janice M. W. Taylor, Kannel, Khan, Lecanu, Madamanchi, Mercer, Ning, Ning, Ogata, Oram, Pandak, Puddu, Pyper, Rae, Ren, Rigamonti, Rone, Rosenson-Schloss, Rupprecht, Schnoor, Schultz, Taylor, Vanhee, Venkateswaran, Wang, Xu, Yelieev, Zeng, Zeng, Zoltan   +46 more
core   +1 more source

Rat plasma lipoproteins: re-evaluation of a lipoprotein system in an animal devoid of cholesteryl ester transfer activity

Journal of Lipid Research, 1982
Plasma lipoproteins from male rats were isolated by rate zonal centrifugation. Four lipoproteins were identified: VLDL, LDL, HDL1, and HDL2. LDL, HLD1, and some HDL2 distributed within the salt density interval of 1.006-1.085 g/ml, while HDL2 was found ...
Y Oschry, S Eisenberg
doaj   +1 more source

Characterization of cholesteryl ester transfer protein inhibitor from plasma of baboons (Papio sp.)

Journal of Lipid Research, 1993
Selective breeding has produced families of baboons that accumulate large high density lipoproteins (HDL1) when challenged with a high cholesterol and high fat (HCHF) diet.
RS Kushwaha, SQ Hasan, HC McGill, Jr, GS Getz, RG Dunham, P Kanda   +5 more
doaj   +1 more source

Cholesteryl Ester Transfer Protein in Metabolic Syndrome [PDF]

Obesity, 2006
AbstractObjective: Low high‐density lipoprotein cholesterol (HDL‐C), hypertriglyceridemia, and small dense‐low density lipoprotein (LDL) are key components of metabolic syndrome (MS). Cholesteryl ester transfer protein (CETP) mediates the transfer of triglycerides (TGs) from TG‐rich lipoproteins to HDL and LDL particles in exchange for cholesteryl ...
Anton, Sandhofer, Susanne, Kaser, Andreas, Ritsch, Markus, Laimer, Julia, Engl, Bernhard, Paulweber, Josef R, Patsch, Christoph F, Ebenbichler   +7 more
openaire   +2 more sources

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C− Kupffer Cell Subsets

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Lipopolysaccharide (LPS) decreases hepatic CETP (cholesteryl ester transfer protein) expression albeit that the underlying mechanism is disputed. We recently showed that plasma CETP is mainly derived from Kupffer cells (KCs). In this study, we
Sam J. L. van der Tuin, Zhuang Li, J. F. Berbée, I. Verkouter, Linda E. Ringnalda, A. Neele, J. V. van Klinken, S. Rensen, Jingyuan Fu, M. D. de Winther, A. Groen, P. Rensen, K. Willems van Dijk, Yanan Wang   +13 more
semanticscholar   +1 more source

Inhibition of lipid transfer by a unique high density lipoprotein subclass containing an inhibitor protein.

Journal of Lipid Research, 1989
We have isolated from human plasma a unique subclass of the high density lipoproteins (HDL) which contains a potent lipid transfer inhibitor protein (LTIP) that inhibited cholesteryl ester, triglyceride, and phospholipid transfer mediated by the lipid ...
T Nishide, J H Tollefson, J J Albers
doaj   +1 more source

Elevation of plasma phospholipid transfer protein in transgenic mice increases VLDL secretion [PDF]

, 2002
Two lipid transfer proteins are active in human plasma, cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Mice by nature do not express CETP.
Crom, M.P.G. (Rini) de, Gent, T. (Teus) van, Haperen, M.J. (Rien) van, Lankhuizen, I.M. (Inge), Lie, J. (Jessica), Scheek, L. (Leo), Tol, A. (Arie) van   +6 more
core   +1 more source

Epitope mapping for the anti-rabbit cholesteryl ester transfer protein monoclonal antibody that selectively inhibits triglyceride transfer

Journal of Lipid Research, 1999
Among the monoclonal antibodies (Mab) against rabbit plasma cholesteryl ester transfer protein (CETP), Mab 14-8F cross-reacted with human CETP and selectively inhibited triglyceride transfer but not cholesteryl ester transfer (Ko, K. W. S., T.
Kazunori Saito, Ki-ichiro Kobori, Hideyuki Hashimoto, Sachiko Ito, Mitsuhisa Manabe, Shinji Yokoyama   +5 more
doaj   +1 more source