Results 81 to 90 of about 32,808 (269)

Influence of different fat emulsions with 10 or 20% MCT/LCT or LCT on lipoproteins in plasma of patients after abdominal surgery [PDF]

open access: yes, 1998
In patients after elective abdominal surgery, different fat emulsions were used to compare their efficacy in total parenteral nutrition and in normalizing plasma lipoprotein levels.
Hailer, Susanne   +2 more
core   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka   +12 more
wiley   +1 more source

Quinoline-3-carboxamide Derivatives as Potential Cholesteryl Ester Transfer Protein Inhibitors

open access: yesMolecules, 2012
A series of novel quinoline-3-carboxamide derivatives <strong>10</strong>–<strong>17</strong> and <strong>23</strong>–<strong>27</strong> were designed and synthesized as cholesteryl ester transfer protein (
Jing-Kang Shen   +8 more
doaj   +1 more source

Circulating PCSK9 levels and CETP plasma activity are independently associated in patients with metabolic diseases [PDF]

open access: yes, 2016
Additional file 1: Figure S1. Correlations between CETP activity and CETP mass (A) and between PCSK9 and CETP mass (B) in patients with T2DM (n=30).
Daiana Ibarretxe   +6 more
core   +2 more sources

Low density lipoproteins develop resistance to oxidative modification due to inhibition of cholesteryl ester transfer protein by a monoclonal antibody

open access: yesJournal of Lipid Research, 2000
Although numerous studies have investigated the relationship between cholesteryl ester transfer protein (CETP) and high density lipoprotein (HDL) remodeling, the relationship between CETP and low density lipoproteins (LDL) is still not fully understood ...
Masahiro Sugano   +4 more
doaj   +1 more source

The structure of latherin, a surfactant allergen protein from horse sweat and saliva [PDF]

open access: yes, 2013
Latherin is a highly surface-active allergen protein found in the sweat and saliva of horses and other equids. Its surfactant activity is intrinsic to the protein in its native form, and is manifest without associated lipids or glycosylation.
Alan Cooper   +6 more
core   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

open access: yesLipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao   +5 more
wiley   +1 more source

The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice. [PDF]

open access: yesPLoS ONE, 2012
Apolipoprotein F (apoF) is 29 kilodalton secreted sialoglycoprotein that resides on the HDL and LDL fractions of human plasma. Human ApoF is also known as Lipid Transfer Inhibitor protein (LTIP) based on its ability to inhibit cholesteryl ester transfer ...
William R Lagor   +11 more
doaj   +1 more source

Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav   +3 more
wiley   +1 more source

Association between diet and polymorphisms in individuals with statin-controlled dyslipidaemia grouped according to oxidative stress biomarkers [PDF]

open access: yes, 2012
The objective of this study was to investigate whether differences in diet and in single-nucleotide polymorphisms (SNPs) found in paraoxonase-1 (PON-1), 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), cholesterol ester transfer protein (CETP ...
Barroso, Lucia Pereira   +5 more
core   +4 more sources

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